Index Catalog // ScholarsArchive@OSU

Environmental DNA reveals cryptic parasite species and gives insight into their fish hosts

Creator:: Phillips, Kyle
Abstract:: Ceratonova shasta is a myxozoan fish parasite that impacts hatchery and wild populations of salmon and trout in the Pacific Northwest. Levels of the parasite in river water can be effectively monitored through direct filtration of parasite spores from water, extraction of total "environmental DNA" (eDNA), then quantitative polymerase chain...
Resource Type:: Honors College Thesis
Full Text:: Review of Biology, 66(4), 411–453. https://doi.org/10.1086/417338 Homel, K., & Alexander, J. D. (2022

Nucleic Acid Based Therapeutics for Treatment of Cystic Fibrosis

Creator:: McKinney, Madison J.
Abstract:: Cystic fibrosis is an inherited genetic disease caused by a single gene mutation in the CFTR protein. Affecting 70,000 people worldwide, this disease is debilitating to patients, resulting in persistent lung infections and decreased quality of life. Due to the various mutation types, there is not currently a single drug...
Resource Type:: Honors College Thesis

Variation in Irc7p activity amongst brewing strains of Saccharomyces cerevisiae

Creator:: Vega, Esteban A.
Abstract:: Polyfunctional thiols are sulfur containing compounds that are important to the flavor and aroma profile of some foods and beverages. S. Cerevisiae has been shown in wine yeast that it is capable of producing these thiols to create a fruity aroma and flavor profile. IRC7, a gene that codes the...
Resource Type:: Honors College Thesis
Full Text:: randomForest. R News 2(3), 18--22. Libkind, D., Hittinger, C. T., Valerio, E., Goncalves, C., Dover, J

Biomechanical Modeling of Isometric Muscle-Tendon Force Generation Through Tendons Coupled in Parallel and a Passive Differential Mechanism

Creator:: Le, Anthony H.
Abstract:: There are at least fifteen types of upper extremity tendon transfer procedures for combined peripheral nerve injuries that involve re-routing a single donor muscle to multiple recipient tendons. As a result, force and movement across finger joints become coupled, resulting in limited grasping abilities. Quantification and modeling of the donor...
Resource Type:: Masters Thesis
Full Text:: on Biomedical Engineering with co-authors, James D. Sweeney and Ravi Balasubramanian

Entrapment of Micro-Algae in Modified Alginate Beads for Oxygen and Nutrient Source

Creator:: Hughson, Jason D.
Abstract:: Presented here is an investigation and comparison of two entrapment methods of algae. Conventional calcium alginate bead entrapment is compared to a recently described modified bead entrapment method, utilizing poly(ethylene glycol) and calcium alginate, which results in void or capillary formation within the beads. It is shown that algal growth...
Resource Type:: Honors College Thesis
Full Text:: microalgae using microencapsulation. Journal of Microencapsulation, 18, 567-575. McHugh, D. J. (1987

Role of P2Y₁₂ Inhibition in PAR1 Stimulated Platelet Dense Granule Release

Creator:: Laschober, Nicole B.
Abstract:: Platelet activation uses a complex set of pathways to respond to vascular injury during hemostasis. However, thrombosis relies on the same set of pathways. Antiplatelet therapies used to prevent thrombotic events often target the P2Y₁₂ platelet receptor for inhibition but can result in bleeding diathesis or in abnormally high ADP...
Resource Type:: Honors College Thesis
Full Text:: . (D) PI3K inhibition has no impact on dense granule release. * indicates statistical significance as

Investigation of the effects of cryopreservation on cellular viability and mechanical integrity of the intervertebral disc

Creator:: Forcier, Ryan J.
Abstract:: Degeneration of the intervertebral disc (IVD) is a phenomenon that has yet to be adequately addressed. Treatment options remain limited and incomplete. The ability to effectively cryopreserve IVDs would allow for better allograft transplantations and storage of samples for research purposes. This study aimed to assess how cryopreservation with different...
Resource Type:: Honors College Thesis
Full Text:: same location. (C and D) Resulting merged images from combining C) live images and D) dead images

Experimental and Mathematical Approaches for Overcoming Mass and Heat Transfer Limitations in Cryopreservation of Vertebral Bodies

Creator:: Forcier, Ryan J.
Abstract:: Successful cryopreservation of bone marrow in situ within vertebral bodies offers an opportunity for quick and convenient storage of a significant quantity of bone marrow stem cells, including hematopoietic- and mesenchymal-type stem cells. However, cryopreservation of more complex large tissues and organs, such as the vertebral body (VB), remains problematic....
Resource Type:: Masters Thesis
Full Text:: AN ABSTRACT OF THE THESIS OF Ryan J. Forcier for

Design and Evaluation of a Vibrotactile Sensory Feedback System for Prostheses

Creator:: Thurston, Tegan J.
Abstract:: Loss of a limb can severely impact everyday way of life. Prosthetics provide a way to return functionality to the user and improve quality of life. However, most prosthetic systems currently available in the market lack sensory feedback making them comparatively more difficult to use resulting in prosthetic abandonment. Therefore,...
Resource Type:: Honors College Thesis
Full Text:: and the United Kingdom. JPO J. Prosthet. Orthot. 19, 55–62 (2007). 8. Biddiss, E., Beaton, D

Developing a Modular Analysis Pipeline to Identify Critical Matrisome Components in Gynecological Disease

Creator:: Cook, Carson J.
Abstract:: The matrisome is an ensemble of genes that are highly relevant for characterizing the behavior of the extracellular matrix (ECM) during the onset and progression of many diseases. Recent advances in the definition of the matrisome, such as The Matrisome Project, have been instrumental in making more advanced resources available...
Resource Type:: Masters Thesis

ScholarsArchive@OSU

Environmental DNA reveals cryptic parasite species and gives insight into their fish hosts

Nucleic Acid Based Therapeutics for Treatment of Cystic Fibrosis

Variation in Irc7p activity amongst brewing strains of Saccharomyces cerevisiae

Biomechanical Modeling of Isometric Muscle-Tendon Force Generation Through Tendons Coupled in Parallel and a Passive Differential Mechanism

Entrapment of Micro-Algae in Modified Alginate Beads for Oxygen and Nutrient Source

Role of P2Y₁₂ Inhibition in PAR1 Stimulated Platelet Dense Granule Release

Investigation of the effects of cryopreservation on cellular viability and mechanical integrity of the intervertebral disc

Experimental and Mathematical Approaches for Overcoming Mass and Heat Transfer Limitations in Cryopreservation of Vertebral Bodies

Design and Evaluation of a Vibrotactile Sensory Feedback System for Prostheses

Developing a Modular Analysis Pipeline to Identify Critical Matrisome Components in Gynecological Disease

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