Index Catalog // ScholarsArchive@OSU

Ibuprofen Treatment Causes NMDA and AMPA Receptor Hyperactivity in Female Wild Type and Heterozygous 5xFAD mice but not Males

Creator:: Rauenhorst, Jacob
Abstract:: With Alzheimer’s disease being the most prominent form of dementia, finding potential treatments for the disease is imperative. This study explored the non-steroidal anti-inflammatory drug ibuprofen as a potential treatment to normalize the hyperactive N-methyl-d-aspartate receptor (NMDAR) within the 5xFAD mice early in the disease pathology before cognitive decline. Female...
Resource Type:: Honors College Thesis
Full Text:: potentials) data. In corroboration with this lab’s previous studies, transgenic female (P<0.0001) and male

Development of Miniature Wire pH Sensors for Real-Time Monitoring of the Streptococcus Mutans Biofilm

Creator:: Wong, Derek C.
Abstract:: The interface between a biofilm and the underlying substrate to which it is attached is challenging to study. Currently, available methods of studying this microenvironment have not been able to record data in real-time over a time period in the range of days. To address this challenge, we report the...
Resource Type:: Honors College Thesis
Full Text:: have not been able to record data in real- time over a time period in the range of days. To address

Structural Similarities and Differences in Tropone and Tropolone: Gas-Phase Electron Diffraction Study

Creator:: Titus, Eric J.
Abstract:: The method of gas-phase electron diffraction is a very useful tool for determining the geometry of a molecule in the gas-phase to a high degree of accuracy. In this thesis, the structures of tropone and tropolone, which are similar molecules that are both based on a 7-carbon ring, were investigated...
Resource Type:: Honors College Thesis
Full Text:: microwave rotational constants as auxiliary data. This experiment was undertaken with two goals in mind

Systematic Review of Prevalence, Risks, and Cultural Differences of Fractures and Falls Among Hispanic Communities

Creator:: Chitwood, Abigail
Abstract:: In the United States, falls are the leading cause of fractures and accidental death in the elderly; 70% of these fractures are women. Hispanic women account for a large population in the US, however data on falls and fractures for these women is lacking. The purpose of this systematic review...
Resource Type:: Honors College Thesis
Full Text:: in the US, however data on falls and fractures for these women is lacking. The purpose of this

Correlation Between Fine Particulate Matter and Traffic Type and Density in Curitiba, Brazil

Creator:: Fantoni, Costanza
Abstract:: Traffic exhaust is an important source of air pollution. This exposure assessment study examined traffic related air pollution in Curitiba, Brazil, and is particularly relevant due to 75% of the population using diesel public transportation. Traffic density was tabulated, and vehicle-type was distinguished based on their fuel type (diesel or...
Resource Type:: Honors College Thesis
Full Text:: increased 0.6333 once the sampling location affected by a rain event from removed from the data set

Implementation of ESOL Standards and Strategies in a High School Chemistry Classroom ESOL Endorsement Work Sample - Unit : Chemical Compositions

Creator:: Duong, Mai
Abstract:: In this work sample, a student teacher implemented ESOL standards and strategies on a unit covering chemical compositions in a high school chemistry classroom. The ELD program at this high school has two types of ELD classes. ELD 1/2 classes have a grammar-based curriculum focused on the English Language, while...
Resource Type:: Honors College Thesis
Full Text:: affected the overall analysis of the data. The work sample concludes with a reflection by the teacher on

Reorientation in Alternative Break Trips

Creator:: Phillips, Caitlin Patricia
Abstract:: When a student participates in a service break trip, a process called reorientation occurs after the trip is over, when the student is trying to connect what they’ve learned on the trip to their normal lives. The objective of this project was to explore the concepts of volunteerism, community service,...
Resource Type:: Honors College Thesis
Full Text:: interview fashion and the data was analyzed to extract major themes about reorientation and its importance

A robust Mycobacterium smegmatis Assay for the Discovery of Anti-tubercular Metabolites from Soil Bacteria

Creator:: Chen, Kathryn P
Abstract:: Tuberculosis (TB) is a pressing global health issue with approximately one third of the world’s population infected by this bacterium. As one of the most dangerous infectious diseases, it has killed approximately 1.7 million people of all ages around the world per year (World Health Organization, 2016). Currently, several drugs...
Resource Type:: Honors College Thesis
Full Text:: . Figure 21: K14/6 fractionation chart and M. smegmatis assay data 34 Figure 22: K14/10

A Dive into the Pacific Fish Microbiome: Exploration of Antibiotics from a Unique Ecosystem

Creator:: Austin, Molly C.
Abstract:: With the rise of resistant bacterial pathogens, currently prescribed antibiotics are rendered useless. In recent years, marine natural products (MNPs) have emerged as novel sources for drug leads. The ocean is a complex environment where marine animals cohabitate with many, and sometimes harmful microorganisms and viruses, but resist infections. Developed...
Resource Type:: Honors College Thesis
Full Text:: …………………………………………………………………………………. ..34 REFERENCES…………………………………………………………………………… ……..35 xii APPENDICES

Bioactivity Screening and Gene Activation Strategies in Fungi

Creator:: Coddington, Nathan C.
Abstract:: Natural products from plants, bacteria, and fungi play an important role in society. Over the last 35 years, natural products and their derivatives have inspired over 60% of all FDA approved small-molecule drugs, and are among the top prescribed therapeutics.1-2 Fleming’s discovery of the fungal antibiotic penicillin started the “Golden...
Resource Type:: Honors College Thesis
Full Text:: ……………………………………………………………32 2.8 Phoma sp. 7204 conclusion…………………………………………………………..34 vii Chapter 3

ScholarsArchive@OSU

Ibuprofen Treatment Causes NMDA and AMPA Receptor Hyperactivity in Female Wild Type and Heterozygous 5xFAD mice but not Males

Development of Miniature Wire pH Sensors for Real-Time Monitoring of the Streptococcus Mutans Biofilm

Structural Similarities and Differences in Tropone and Tropolone: Gas-Phase Electron Diffraction Study

Systematic Review of Prevalence, Risks, and Cultural Differences of Fractures and Falls Among Hispanic Communities

Correlation Between Fine Particulate Matter and Traffic Type and Density in Curitiba, Brazil

Implementation of ESOL Standards and Strategies in a High School Chemistry Classroom ESOL Endorsement Work Sample - Unit : Chemical Compositions

Reorientation in Alternative Break Trips

A robust Mycobacterium smegmatis Assay for the Discovery of Anti-tubercular Metabolites from Soil Bacteria

A Dive into the Pacific Fish Microbiome: Exploration of Antibiotics from a Unique Ecosystem

Bioactivity Screening and Gene Activation Strategies in Fungi

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