Chlorinated and non-chlorinated solvents are used in a variety of industrial processes and as a consequence, they have become environmental contaminants as well. Because of this, they lead to both occupational and environmental exposures. Exposure to these compounds can potentially result in various forms of neurological damage with a wide...
The bovine blastocyst is composed of a one-celled layer of trophectoderm
surrounding a fluid filled sac called the blastocoel and a ball of cells called the inner cell
mass (ICM). On Day 8 (Day 0=fertilization) in bovine embryos, endodermal cells leave
the ICM, migrate over the extracellular matrix (ECM) on...
Consider a simple Markov process on [0,T]. The occupation times were extensively studied in the case of T increasing to infinity. Here we develop a method of computing the distribution for occupation times when T is small via integral equations and integral transforms.
The endoplasmic reticulum (ER) is a crucial organelle in the cell where protein folding and processing occurs, and conditions that negatively affect ER functions are highly detrimental to the cell. The accumulation of unfolded/misfolded proteins in the ER leads to a condition known as ER Stress. The ER has developed...
Intimate partner violence is the systematic, intentional use of physical, emotional and/or sexual abuse that one person in a domestic relationship exerts over their partner in order to maintain power and control. In our society, we tend to focus on the external evidence of intimate partner violence such as the...
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White muscle disease (WMD), a degenerative muscle disease brought on by a deficiency of the essential trace nutrient selenium, is thought to be mediated by the protein Selenoprotein W (SeW). In its relationship with WMD, SeW, like many selenoproteins, binds to glutathione, serving some purpose in redox mechanisms...
Mammary tumors are the third most common tumor in cats after cutaneous neoplasia and lymphosarcoma. More than 80% of feline mammary tumors are adenocarcinomas, which are similar to human mammary adenocarcinomas in their biologic behavior and histologic characteristics. Despite treatment with radical mastectomy, feline mammary adenocarcinoma is associated with a...
The AhR is a ligand-activated transcription factor that mediates the potent immunosuppressive effects of TCDD. AhR-dependent changes in gene expression appear to alter the differentiation of CD4+ T cells to induce a population of CD4+CD25+ T regulatory cells (Tregs) that suppress the immune response. Ascertaining if and how the AhR...
It is commonly accepted that for the analysis of wood beams, the neutral axis coincides with the centroid of the beam. Although this assumption is used in analysis, wood is not an isotropic material, as it has different elastic properties in the tangential, radial and longitudinal directions, nor is it...
Although thousands of volunteers from the United States go abroad each year to teach English, many are unprepared for their experiences. Undergraduate students teaching in a foreign country seem to lack training in educational methodology or foreign relations that would prepare them for teaching and living abroad. This project was...
The Harderian gland (HG) of the red-sided garter snake, Thamnophis sirtalis parietalis, is a secretory structure that plays a role in the vomeronasal system by solubilizing semiochemicals such as prey chemoattractants and the female sexual attractiveness pheromone. The HG produces secretions containing pheromone-binding proteins that form a complex with pheromone...
Inflammation is one of the first, most important responses of the immune system when presented with infection and is mediated primarily by eicosanoids and cytokines. The goal of this research was to generate monoclonal antibodies against murine IL17C, a poorly characterized cytokine involved in inflammation and linked to inflammatory conditions....
Twenty seven modern (top 1-2cm) sediment samples from multicores retrieved from throughout coastal SE Alaska were analyzed for their organic matter content and the source composition. Total organic carbon (TOC) as well as biogenic silica (bioSi), and calcium carbonate (CaCO3) content were analyzed to evaluate the organic matter content and...
As genetically modified products come under greater production, tensions surrounding the potential benefits and harms of the technology have appeared in divergent policy between the European Union (EU) and certain member states. The purpose of this thesis is to consider whether some type of international law, also called an environmental...
Lynch individuals have a predisposition to developing colorectal and other cancers due to inherited defects in their mismatch repair (MMR) system. Although mutations in MMR have been directly implicated in Lynch Syndrome, the precise mechanism(s) of MMR functions have yet to be elucidated. One essential complex, MutL (a dimer of...
Vox comm is a digital wireless, voice-operated personal communicator developed as an electrical engineering Senior Design project. It is designed to provide a method for hassle-free, short-range communication. The product platform boasts of low power and small size for a host of usage models. This thesis details the product design...
This study compares the accounting standards of three different entities, the United Kingdom Generally Accepted Accounting Principles, the domestic accounting standards of France, and the International Financial Reporting Standards (IFRS). The analysis consists of a comparison between two companies, British Airways and Air France – KLM, for FY 2005, specifically...
Empowering pedagogy (also know as “transgressive,” “emancipatory,” or “democratic” forms of education) seeks to challenge the historically oppressive tendencies of traditional education. As a student of Social Justice and International Studies, I approach the topic of empowering pedagogy through a case study. My research explored this non-traditional educational philosophy and...
An inducible, mutant virus, designated vvtetO:I7L/G1L, was used to study the morphogenic proteolysis step of the vaccinia virus life cycle. The vvtetO:I7L/G1L controlled the expression of two genes, I7L, a cysteine proteinase, and G1L, a putative metalloproteinase. These proteins are involved in the maturation of viral core proteins, p4a, p4b,...
Rhodococcus fascians is a Gram-positive, pleiomorphic actinomycete that causes leafy gall formation in a wide range of plant hosts. This particular phytopathogen has been a focus of research at the Oregon State University Plant Clinic, a diagnostic laboratory. Phylogeny of R. fascians isolates obtained from Plant Clinic submissions was determined...