Index Catalog // ScholarsArchive@OSU

Look Ma, no beads: Analyzing traction force characteristics of migratory adenocarcinoma in heterogeneous type-1 collagen through bead-free confocal microscopy

Creator:: Groves, Nicholas Scott
Abstract:: Current methods in traction force analysis rely on a homogeneous extra-cellular matrix and embedded microbeads to track deformations. The efficacy of these methods decreases when the matrix is not homogeneous. In heterogeneous matrices, beads often aggregate in regions of higher matrix density and float in regions where matrix substrate is...
Resource Type:: Undergraduate Thesis
Full Text:: confocal microscopy Nicholas Scott Groves Advisor: Prof. Bo Sun May 30, 2016 1 Abstract Current

State-of-the-Art Combination Therapies and Nanomedicines for Triple Negative Breast Cancer

Creator:: Fabbi, Meagan C.
Abstract:: Triple-negative breast cancer (TNBC) is a particularly aggressive molecular subtype of malignant cells that tends to proliferate quickly and is commonly resistant to traditional chemotherapy leading to relapses in prognosis more frequently than other forms of breast cancer (BCa) [1][2][3]. Current treatment options include surgical resection of cancerous tissue and...
Resource Type:: Honors College Thesis
Full Text:: Cancer Abstract approved: _______________________________________________________ Conroy Sun

Transcription Factors Associated with Tomato Seed Germination

Creator:: Sun, Jing
Abstract:: Seed germination is strictly defined as the physiological events before radicle protrusion through the endosperm cap, the endosperm region adjacent to the radicle tip. There are two opposing forces governing seed germination: the growth potential of the embryo and the mechanical resistance of the endosperm cap. The endosperm cap cell...
Resource Type:: Honors College Thesis
Full Text:: THE THESIS OF Jing Sun for the degree of Honors Baccalaureate of Science in Microbiology presented

Optimization of NH2-MIL-88B (Fe) for reactive oxygen species generation

Creator:: Shotton, Lewis
Abstract:: Metal-organic frameworks (MOFs) have emerged as promising candidates in novel cancer therapies due to their unique properties, including high surface area, tunable crystal size, and exposed metal ion active sites for catalysis. The MOF NH2-MIL-88B has shown potential use in cancer theranostics. Its open metal active sites catalyze the reduction...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Conroy Sun, Committee Member, representing School of Pharmacy

Computational study of the electrostatic interaction between kinesin-5/BimC and the microtubule

Creator:: Chen, Zishi
Resource Type:: Undergraduate Thesis
Full Text:: . [12] Guo, W., Sun, S., Sanchez, J. E., Lopez-Hernandez, A. E., Ale, T. A., Chen, J., Afrin, T., Qiu

Nucleic Acid Based Therapeutics for Treatment of Cystic Fibrosis

Creator:: McKinney, Madison J.
Abstract:: Cystic fibrosis is an inherited genetic disease caused by a single gene mutation in the CFTR protein. Affecting 70,000 people worldwide, this disease is debilitating to patients, resulting in persistent lung infections and decreased quality of life. Due to the various mutation types, there is not currently a single drug...
Resource Type:: Honors College Thesis
Full Text:: Robinson. Dr. Conroy Sun provided in vivo lung biodistribution studies, paper was written by Ema

Incorporation of polymorphic spacers to inhibit sintering of SrO/SrCO3 for thermochemical energy storage

Creator:: Tran, Justin T
Abstract:: Global energy needs are continuously increasing while fossil fuels remain an uncertain resource. With a growing population and demand for energy, alternative energy sources are being pursued to power the future. Fossil fuels are an unsustainable resource that brings along problems of climate change and atmospheric pollution. Concentrated solar power...
Resource Type:: Honors College Thesis
Full Text:: increase efficiency in power generation and allow for generation beyond on-sun hours. One method of TES

Effect of Solar System Models on Pulsar Timing Experiments

Creator:: Nicolaysen, Cooper
Abstract:: Gravitational wave (GW) astronomy is a key ingredient in confirming Einstein’s theory of General Relativity and showing how the universe sends ripples through spacetime, distorting distances between two points. The confirmation of high-frequency GWs observed by The Laser Interferometer Gravitational-Wave Observatory (LIGO) in 2015 was a breakthrough in our understanding...
Resource Type:: Undergraduate Thesis
Full Text:: travel time distortion due to earth- sun orbit radii changing, between the two models. We show that the

Differential Binding and Structural Properties of the WWC Protein Family

Creator:: Rodriguez, Diego Javier
Abstract:: The WWC family consists of three proteins‐ KIBRA/WWC1, WWC2, and WWC3. The three proteins share a similar primary structure and interact with a common set of proteins. Each paralog contains two WW domains which recognize proline‐rich sequences of the type PPxY (P is proline, Y is tyrosine, x is any...
Resource Type:: Honors College Thesis
Full Text:: pathway (Chen and Liu, 2018; Han et al., 2018; Han et al., 2017; Hou and Zhou, 2017; Wennmann et al

Functional consequences of microRNA regulation by polycyclic aromatic hydrocarbons in 3D human bronchial epithelial cells

Creator:: Mans, Michael-Andres D.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are a class of contaminants ubiquitous in the environment and result from the incomplete combustion of fossil fuels. Many PAHs have been identified as procarcinogenic, and are metabolized to form DNA adducts; however, other mechanisms also may contribute to toxicity and help explain differences in toxicity...
Resource Type:: Undergraduate Thesis
Full Text:: /articles/PMC5759260/. Chen S, Li P, Yang R, Cheng R, Zhang F, Wang Y, Chen X, Sun Q, Zang W, Du Y, et al

ScholarsArchive@OSU

Look Ma, no beads: Analyzing traction force characteristics of migratory adenocarcinoma in heterogeneous type-1 collagen through bead-free confocal microscopy

State-of-the-Art Combination Therapies and Nanomedicines for Triple Negative Breast Cancer

Transcription Factors Associated with Tomato Seed Germination

Optimization of NH2-MIL-88B (Fe) for reactive oxygen species generation

Computational study of the electrostatic interaction between kinesin-5/BimC and the microtubule

Nucleic Acid Based Therapeutics for Treatment of Cystic Fibrosis

Incorporation of polymorphic spacers to inhibit sintering of SrO/SrCO3 for thermochemical energy storage

Effect of Solar System Models on Pulsar Timing Experiments

Differential Binding and Structural Properties of the WWC Protein Family

Functional consequences of microRNA regulation by polycyclic aromatic hydrocarbons in 3D human bronchial epithelial cells

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Creator

Contributor

Date

Decade

Degree Field

Degree Level

Degree Name

File Format

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search