Pediatricians and other physicians in the United States identify themselves with various religious or spiritual affiliations and use its practices and customary ways to influence their medical practice. Pediatricians and physicians affiliated in the pediatric medical field have an important role in monitoring the health of many children, teenagers, and...
Chlamydia possesses an immense importance within both human and animal medicine when looking at pathogens. Chlamydia trachomatis infections have been shown to affect both the eye and genital tracts in millions of humans and animals every year [13]. As C. trachomatis strains are highly conserved in patients, it has made...
Our laboratory is exploring the mechanism of action of a novel broad spectrum antiviral, ST-669. This compound has activity against a variety of different viruses and the obligate intracellular bacterium, Chlamydia. In this study, we explored the effects of ST-669 when the cell cycle of the host cells was altered....
Chlamydia trachomatis is an obligate intracellular pathogen that affects millions of people worldwide via ocular or reproductive tract infection. Despite obvious differences in site of infection, there has been shown to be high levels of sequence conservation across C. trachomatis. This high level of sequence conservation is hindered with a...
Chlamydia trachomatis is an obligate intracellular bacterium that causes diseases of the eye and urogenital tract in humans. It is the cause of the sexual transmitted infection (STI) chlamydia, the most prevalent STI worldwide, and the ocular disease trachoma, the leading cause of infectious blindness. To date there is no...
Although U.S. Latin@s are more affected by major depressive disorder than non-Latin@ whites, they are less likely to utilize mental health services. The purpose of this project is to create a children’s book that promotes the utilization of mental health services among U.S. Latin@s with major depressive disorder. This book...
Enduracidin is an antibiotic produced by Streptomyces fungicidicus that is effective against Gram-positive bacteria. Previous work identified seventy-eight mutations in an S. fungicidicus strain that produces a significantly higher level of enduracidin than the wild type strain, ATCC 21013. Eleven mutations were analyzed individually to identify those that may contribute...
This thesis consists of two papers in manuscript format. The first paper presents optical measurements of tsunami inundation through an urban waterfront in a laboratory wave basin. The physical model was constructed at 1:50 scale and was an idealization of the town of Seaside, Oregon. The paper presents an analysis...
Chlamydia abortus, an intracellular bacterium, spreads through flocks of sheep and goats, causing ovine enzootic abortion (OAE). Chlamydiae develop within a pathogen-modified vacuole in the host cell called the inclusion, which allows the bacteria to acquire host resources. The morphology of the inclusion varies between chlamydial species. Some species fuse...
Chlamydiae encode a family of proteins named the polymorphic membrane proteins, or Pmps, whose role in infection and pathogenesis is unclear. The Rockey Laboratory is studying polymorphic membrane protein expression in Chlamydia abortus, a zoonotic pathogen that causes abortions in ewes. C. abortus contains 18 pmp genes, some of which...