Motivation: It can take considerable amounts of time and effort to use existing computational tools to analyze a small RNA sequence for the purpose of determining if it is characteristic of microRNA. It is similarly tedious to search for homologs to known microRNA sequences in the rapidly growing collection of...
Chlamydia possesses an immense importance within both human and animal medicine when looking at pathogens. Chlamydia trachomatis infections have been shown to affect both the eye and genital tracts in millions of humans and animals every year [13]. As C. trachomatis strains are highly conserved in patients, it has made...
Our laboratory is exploring the mechanism of action of a novel broad spectrum antiviral, ST-669. This compound has activity against a variety of different viruses and the obligate intracellular bacterium, Chlamydia. In this study, we explored the effects of ST-669 when the cell cycle of the host cells was altered....
Our laboratory group is studying the molecular target of a novel, broad-spectrum antiviral compound known as ST-669. This compound has activity against a variety of different viruses and also obligate intracellular bacteria in the genera Coxiella and Chlamydia. The goal of this thesis project was to help elucidate the mechanism...
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Daniel Rockey
Our laboratory group is studying the molecular target of a novel, broad
Although U.S. Latin@s are more affected by major depressive disorder than non-Latin@ whites, they are less likely to utilize mental health services. The purpose of this project is to create a children’s book that promotes the utilization of mental health services among U.S. Latin@s with major depressive disorder. This book...
This thesis consists of two papers in manuscript format. The first paper presents optical measurements of tsunami inundation through an urban waterfront in a laboratory wave basin. The physical model was constructed at 1:50 scale and was an idealization of the town of Seaside, Oregon. The paper presents an analysis...
Chlamydia trachomatis is an obligate intracellular bacterium that causes diseases of the eye and urogenital tract in humans. It is the cause of the sexual transmitted infection (STI) chlamydia, the most prevalent STI worldwide, and the ocular disease trachoma, the leading cause of infectious blindness. To date there is no...
Chlamydia abortus, an intracellular bacterium, spreads through flocks of sheep and goats, causing ovine enzootic abortion (OAE). Chlamydiae develop within a pathogen-modified vacuole in the host cell called the inclusion, which allows the bacteria to acquire host resources. The morphology of the inclusion varies between chlamydial species. Some species fuse...
Pediatricians and other physicians in the United States identify themselves with various religious or spiritual affiliations and use its practices and customary ways to influence their medical practice. Pediatricians and physicians affiliated in the pediatric medical field have an important role in monitoring the health of many children, teenagers, and...
Chlamydia trachomatis is an obligate intracellular pathogen that affects millions of people worldwide via ocular or reproductive tract infection. Despite obvious differences in site of infection, there has been shown to be high levels of sequence conservation across C. trachomatis. This high level of sequence conservation is hindered with a...