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The effect of selenium deficiency on the fatty acid metabolism of rats and lambs

Creator:: Fischer, William Carl
Abstract:: Selenium deficiency in rats results in increased carbon metabolism, approaching twice the rate of selenium supplemented animals (normal). This is also reflected in a 50 percent increase in lysosomal enzyme activity in tissues of selenium deficient animals. Isolation of rat liver lysosomes shows a 17 percent increase in membrane thickness...
Resource Type:: Dissertation
Full Text:: deep appreciation to Dr. Philip D. Whanger for his help and encouragement in the preparation of this

Selenium-75 incorporation in semen and reproductive organs of the bull and ram

Creator:: Pond, Finn Richard
Resource Type:: Dissertation
Full Text:: Philip D. Whanger Following initial intramuscular injections of 500 pCi 75 Se, semen was collected

Interaction of selenium with cadmium and mercury in semen and reproductive tissues: in vivo and in vitro studies

Creator:: Alabi, Nathaniel Sigismund
Abstract:: Studies were conducted to investigate the metabolism of selenium (Se) , and the influences of Se on the metabolism of cadmium (Cd) and inorganic mercury (Hg) in rats, and in ram semen in vitro. Se-deficient (-Se) or Se-adequate (+Se) rats were injected intraperitoneally with either ¹⁰⁹CdCl₂ (5 μCi/rat) or ²⁰³HgN0₃...
Resource Type:: Dissertation
Full Text:: IN VITRO STUDIES Abstract approved: Redacted for Privacy Philip D. Whanger Studies were conducted

Absorption and metabolism of selenite by perfused small intestine, and hepatocytes from rats

Creator:: Park, Yeong-Chul
Resource Type:: Dissertation
Full Text:: Selenite by Perfused Small Intestine. and Hepatocytes from Rats Abstract approved: Philip D. Whanger

The effect of vitamin B₁₂ on selenium and arsenic metabolism

Creator:: Chen, Chiareiy Liu
Resource Type:: Dissertation
Full Text:: B12 on Selenium and Arsenic Metabolism Redacted for Privacy Abstract approved: Philip D. Whanger

The influence of selenium on selenoprotein W

Creator:: Yeh, Jan-ying
Abstract:: The objective of our study was to investigate the effect of selenium on selenoprotein W. Western blot analysis indicated that selenoprotein W is present in muscle, brain, testis and spleen of rat tissues. Tissue distribution of selenoprotein W was not altered in rats fed various selenium levels. Among muscle, brain,...
Resource Type:: Dissertation
Full Text:: Redacted for Privacy ACKNOWLEDGEMENTS I would like to thank Dr. Philip D. Whanger, my mentor, for his

Biochemical and molecular characteristics of selenoprotein W

Creator:: Gu, Qiu-Ping
Resource Type:: Dissertation
Full Text:: Abstract approved: Philip D. Whanger The objective of this study was to further characterize

Selenoprotein W : distribution and function in rat tissue and cultured cells

Creator:: Sun, Yu, 1963-
Abstract:: The objective of this study was to further determine the distribution of selenoprotein W (SeW) in tissues from rats and sheep fed different selenium levels and to search for the possible functions of this protein. In the rat study a total of 28 rat tissues were examined and SeW was...
Resource Type:: Dissertation
Full Text:: would like to express my sincere thanks to Dr. Philip D. Whanger, my mentor, for his dedicated teaching

Characterization of rodent selenoprotein W promoter

Creator:: Amantana, Adams
Abstract:: Rat selenoprotein W (SeW) promoter activity was investigated using different concentrations of cadmium, copper, and zinc. Two fragments (404bp and 1265bp) of the SeW promoter, containing a single metal response element (MRE), were ligated into the multiple cloning site of a pGL3-Basic reporter plasmid. The constructs were transfected into cultured...
Resource Type:: Dissertation
Full Text:: Selenoprotein W Promoter Abstract approved: Philip D. Whanger Rat selenoprotein W (SeW) promoter activity was

Selenoprotein W : Purification and characterization of its interaction with calmodulin

Creator:: Bauman, Andrew Thomas
Abstract:: Selenoprotein W (SeW) is a protein whose function is unknown, but potentially plays a vital role in calcium metabolism, as an indirect link has been established with white muscle disease (WMD). White muscle disease occurs in selenium deficient animals, and is characterized by the precipitation of calcium in muscle, leading...
Resource Type:: Dissertation
Full Text:: : Purification and Characterization of its Interaction with Calmodulin. Abstract approved: Philip D. Whnger

ScholarsArchive@OSU

The effect of selenium deficiency on the fatty acid metabolism of rats and lambs

Selenium-75 incorporation in semen and reproductive organs of the bull and ram

Interaction of selenium with cadmium and mercury in semen and reproductive tissues: in vivo and in vitro studies

Absorption and metabolism of selenite by perfused small intestine, and hepatocytes from rats

The effect of vitamin B₁₂ on selenium and arsenic metabolism

The influence of selenium on selenoprotein W

Biochemical and molecular characteristics of selenoprotein W

Selenoprotein W : distribution and function in rat tissue and cultured cells

Characterization of rodent selenoprotein W promoter

Selenoprotein W : Purification and characterization of its interaction with calmodulin

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