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Filtering by: Creator Knowlton, C. W. Remove constraint Creator: Knowlton, C. W. Degree Name Doctor of Philosophy (Ph.D.) Remove constraint Degree Name: Doctor of Philosophy (Ph.D.)

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  • The ascorbic acid requirements of older adolescents

    Creator:
    Davey, Bessie Louise
    Abstract:
    The concentration of ascorbic acid in the plasma was determined on four levels of ascorbic acid intake for seven day periods in 1946-47 and on three levels of ascorbic acid intake for ten day periods in 1947-48. The subjects, eight girls and eight boys, were 16 to 19 year old...
    Resource Type:
    Dissertation
    Full Text:
    . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 60 C. Total Daily Intake of Ascorbic Acid and Daily Plasma Ascorbic Acid Values for Adolescent Boys

  • The influence of selenium on selenoprotein W

    Creator:
    Yeh, Jan-ying
    Abstract:
    The objective of our study was to investigate the effect of selenium on selenoprotein W. Western blot analysis indicated that selenoprotein W is present in muscle, brain, testis and spleen of rat tissues. Tissue distribution of selenoprotein W was not altered in rats fed various selenium levels. Among muscle, brain,...
    Resource Type:
    Dissertation
    Full Text:
    The influence of selenium on selenoprotein W AN ABSTRACT OF

  • Some potential mechanisms for finely-tuned regulation of phospholipase C-β isozymes : studies of dimerization and phosphatidylinositol 3,4,5-trisphosphate activation

    Creator:
    Zhang, Yong
    Abstract:
    Phospholipase C-β (PLC-β) isozymes are key effectors in G protein-coupled signaling pathways. Prior research suggested that some isoforms of PLC-β may exist and function as dimers, but little is known about dimerization of PLC-β. Data from coimmunoprecipitation assays of differentially-tagged PLC-β constructs and sizeexclusion chromatography of native PLC-β support homodimerization...
    Resource Type:
    Dissertation
    Full Text:
    Phospholipase C-β Isozymes: Studies of Dimerization and Phosphatidylinositol 3,4,5-Trisphosphate Activation

  • Biochemical and molecular characteristics of selenoprotein W

    Creator:
    Gu, Qiu-Ping
    Resource Type:
    Dissertation
    Full Text:
    202APPENDIX C. CALCIUM BINDING ASSAY LIST OF FIGURES Figure Page 2-1 Selenprotein W cDNA sequences

  • Characterization of rodent selenoprotein W promoter

    Creator:
    Amantana, Adams
    Abstract:
    Rat selenoprotein W (SeW) promoter activity was investigated using different concentrations of cadmium, copper, and zinc. Two fragments (404bp and 1265bp) of the SeW promoter, containing a single metal response element (MRE), were ligated into the multiple cloning site of a pGL3-Basic reporter plasmid. The constructs were transfected into cultured...
    Resource Type:
    Dissertation
    Full Text:
    Selenoprotein W Promoter Abstract approved: Philip D. Whanger Rat selenoprotein W (SeW) promoter activity was

  • Ascorbylation- the biological relevance of covalently bound ascorbic acid

    Creator:
    Kesinger, Nicholas G.
    Abstract:
    Ascorbic acid, or vitamin C, is well known as a co-factor for proline-hydroxylase and as an anti-oxidant. However, it is also capable of forming covalent bonds, particularly in the role of a nucleophile, henceforth termed 'ascorbylation'. The ascorbylation of electrophiles can occur under physiological conditions. Furthermore, there are a number...
    Resource Type:
    Dissertation
    Full Text:
    approved: ___________________________ Dr. Jan F. Stevens Ascorbic acid, or vitamin C, is well known

  • Regulation of phospholipase C-beta isozymes by calmodulin

    Creator:
    McCullar, Jennifer Star
    Abstract:
    Phospholipase C-Jβ (PLCβ) is an important effector enzyme in G-protein-coupled signaling pathways. Activation of PLCβ by Gα and Gβy subunits has been fairly well characterized, but little is known about other protein interactions that may also regulate PLCβ function. A yeast two-hybrid screen of a mouse brain cDNA library with...
    Resource Type:
    Dissertation
    Full Text:
    . Title: Regulation of Phoshoplipase C-beta isozymes by Calmodulin A Abstract approved: Theresa M. Filtz

  • Selenoprotein W : Purification and characterization of its interaction with calmodulin

    Creator:
    Bauman, Andrew Thomas
    Abstract:
    Selenoprotein W (SeW) is a protein whose function is unknown, but potentially plays a vital role in calcium metabolism, as an indirect link has been established with white muscle disease (WMD). White muscle disease occurs in selenium deficient animals, and is characterized by the precipitation of calcium in muscle, leading...
    Resource Type:
    Dissertation
    Full Text:
    Selenoprotein W ..................................... 119 6. Appendix C: Does Selenoprotein W Bind Calcium

  • Rainbow trout cystatin C : gene expression, heterologous production and characterization

    Creator:
    Li, Fugen
    Abstract:
    Rainbow trout cystatin C cDNA has been isolated from trout liver. The full-length cystatin cDNA (674 bp) included the 5'untranslated region and the polyadenylation signal sequence AATAAA in the 3' region. Translation of the cDNA defines 132 amino acid residues. Comparison of the amino acid sequence with those of family...
    Resource Type:
    Dissertation
    Full Text:
    C: Gene Expression, Heterologous Production and Characterization. Abstract approved: David W

  • A physiological approach to a rapid method for identifying C. botulinum

    Creator:
    Dyer, John Kaye
    Abstract:
    Disc gel electrophoresis of the vegatative cell -free extracts ofstrains of Clostridium botulinum types A, B, C, E, and F and therelated nontoxic group showed limited value as a means for identifyingthese closely related microorganisms, since separation,though not consistent in all cases, could only be based on the numberof protein...
    Resource Type:
    Dissertation
    Full Text:
    TO A RAPID METHOD FOR IDENTIFYING C, BOTULINUM MMIIIMMMI Abstract appr coed: Arthur W. Anderson