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Filtering by: Creator Fernández, Natalia Remove constraint Creator: Fernández, Natalia Degree Name Doctor of Philosophy (Ph.D.) Remove constraint Degree Name: Doctor of Philosophy (Ph.D.)

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  • Harnessing the Potential of Gut Microbiome in the Context of Type 2 Diabetes

    Creator:
    Gurung, Manoj
    Abstract:
    Gut microbiota plays an essential role in health and diseases, a fact already established. With the explosive increase in obesity and its main complication, Type 2 Diabetes Mellitus (T2D), there is an immediate need for novel methods of diagnosis, prevention and treatment of these conditions. In the last one and...
    Resource Type:
    Dissertation
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    Diabetes Abstract approved: ______________________________________________________ Natalia

  • Western Diet-Induced Nonalcoholic Steatohepatitis (NASH): The Impact of Time on the Onset and Remission of Disease

    Creator:
    Spooner, Melinda H.
    Abstract:
    Nonalcoholic fatty liver disease (NAFLD) is characterized by an accumulation of neutral lipids in the form of triglycerides and cholesterol esters accounting for >5% of liver weight. Excess neutral lipids accumulate in large lipid droplets, i.e., macrosteatosis, displacing the nucleus of cells. Current theory suggests neutral lipid accumulation is the...
    Resource Type:
    Dissertation
    Full Text:
    endeavors of lifelong learning. Next, my committee members Dr. Emily Ho, Dr. Natalia Shulzhenko, Dr

  • Crossing Boundaries during Stress Responses: Antigen Presentation by Adaptive and Innate MHC Class I Molecules

    Creator:
    Nagamine, Brandy S.
    Abstract:
    The immune system is a complex network of cellular processes working in harmony to guard us against pathogenic attack. Of utmost importance is the ability of the immune system to discriminate between “self” and “non-self” and diseased versus healthy. Recognition of antigens complexed to major histocompatibility complex (MHC) molecules is...
    Resource Type:
    Dissertation
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    . I am thankful to my committee members, Dr. Natalia Shulzhenko and Dr. Theresa Filtz, for their

  • Towards a Better Understanding of How the Dietary Supplement Xanthohumol Can Improve Health

    Creator:
    Logan, Isabelle E.
    Abstract:
    Xanthohumol, a prenylated flavonoid found in hops and beer, possesses a long-standing reputation to improve health. Xanthohumol’s cytotoxicity to a wide variety of cancer cell lines is well-established. Herein we provide further insight into the cytotoxicity of not only xanthohumol, but also its non-estrogenic derivatives, to a number of colonic...
    Resource Type:
    Dissertation
    Full Text:
    . Thank you to my advising committee members, Drs. Gerd Bobe, Siva Kolluri, Viviana Pérez, Natalia

  • “We Don’t Stop ‘til We Get There”: Reframing the Hip Hop Ill-literacies of Latinx Youth

    Creator:
    Cole, Matthew C.
    Abstract:
    The experiences of Latinx youth are well-studied in U.S. schools, yet, few studies have focused on their experiences in Community Based Educational Spaces (CBES). CBES continue to be on the periphery of Education research despite the potential affordances of youth-led work in such out-of-school spaces (Baldridge, 2020). At the same...
    Resource Type:
    Dissertation

  • Rural Hispanic-Serving Institutional Context on the Development of Hispanic-Serving Initiatives and Strategies

    Creator:
    Alvarado-Young, Kelly M.
    Abstract:
    The focus of this single-site case study was to explore how rural dispersed Hispanic-serving community colleges in the Pacific Northwest support the development of Hispanic-Serving initiatives and strategies. The conceptual frameworks of Latino critical theory and the multicultural organizational development model were used to analyze and interpret the data. Interviews...
    Resource Type:
    Dissertation
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    , and California (Excelencia in Education, 2015; Martinez & Fernandez, 2004; Núñez, Crisp, & Elizondo

  • Polymeric submicron optical ion-selective sensors

    Creator:
    Bychkova, Valeriya
    Abstract:
    Ion-selective polymeric optical sensors – ion optodes – are a promising alternative to ion-selective electrodes and fluorescent dyes for analytical and biological applications, e.g. extra- and intracellular measurements. They are non-toxic, highly selective robust probes for ionic fluxes monitoring. A large-scale fabrication of ion optodes using a solvent displacement method...
    Resource Type:
    Dissertation
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    members: Hasini Perera, Katy Fordyce and Natalia Pylypiuk for their friendship and advice. I extend my

  • Soil Moisture Encodes Plant Water Use Strategies

    Creator:
    Bassiouni, Maoya
    Abstract:
    Resilient water, food, and energy management strategies for an ever-growing population and changing environment depends on our understanding of water and carbon cycles from local to global scales. Fluxes of water and carbon are coupled by photosynthesis and plant transpiration cycles the largest fraction of terrestrial water from the land...
    Resource Type:
    Dissertation

  • Volatile composition of Pinot Noir grapes and wines under different viticultural practices in western Oregon

    Creator:
    Feng, Hui
    Abstract:
    High vegetative growth of Pinot Noir vine is a common problem in most vineyards of Oregon's Willamette Valley, where sunlight exposure and heat accumulation are limited. Consequently, growers in this region commonly use vineyard management strategies to regulate vine vigor and improve grape and wine quality. Wine quality is greatly...
    Resource Type:
    Dissertation
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    to thank them for their contributions. I thank people from E&J Gallo winery: Natalia

  • Sensor Interface Circuit Design towards CMOS Scaling

    Creator:
    Liu, Jialin
    Abstract:
    Sensor system plays an important role in connecting everything including human body to the electrical information systems that we have built and that we are going to build, to make the world more intelligent and efficient. One of the key propulsive forces behind these emerging techniques is CMOS scaling that...
    Resource Type:
    Dissertation