Inflammation is one of the first, most important responses of the immune system when presented with infection and is mediated primarily by eicosanoids and cytokines. The goal of this research was to generate monoclonal antibodies against murine IL17C, a poorly characterized cytokine involved in inflammation and linked to inflammatory conditions....
Consider a simple Markov process on [0,T]. The occupation times were extensively studied in the case of T increasing to infinity. Here we develop a method of computing the distribution for occupation times when T is small via integral equations and integral transforms.
The Harderian gland (HG) of the red-sided garter snake, Thamnophis sirtalis parietalis, is a secretory structure that plays a role in the vomeronasal system by solubilizing semiochemicals such as prey chemoattractants and the female sexual attractiveness pheromone. The HG produces secretions containing pheromone-binding proteins that form a complex with pheromone...
The endoplasmic reticulum (ER) is a crucial organelle in the cell where protein folding and processing occurs, and conditions that negatively affect ER functions are highly detrimental to the cell. The accumulation of unfolded/misfolded proteins in the ER leads to a condition known as ER Stress. The ER has developed...
Lynch individuals have a predisposition to developing colorectal and other cancers due to inherited defects in their mismatch repair (MMR) system. Although mutations in MMR have been directly implicated in Lynch Syndrome, the precise mechanism(s) of MMR functions have yet to be elucidated. One essential complex, MutL (a dimer of...
Vox comm is a digital wireless, voice-operated personal communicator developed as an electrical engineering Senior Design project. It is designed to provide a method for hassle-free, short-range communication. The product platform boasts of low power and small size for a host of usage models. This thesis details the product design...
It is commonly accepted that for the analysis of wood beams, the neutral axis coincides with the centroid of the beam. Although this assumption is used in analysis, wood is not an isotropic material, as it has different elastic properties in the tangential, radial and longitudinal directions, nor is it...
An inducible, mutant virus, designated vvtetO:I7L/G1L, was used to study the morphogenic proteolysis step of the vaccinia virus life cycle. The vvtetO:I7L/G1L controlled the expression of two genes, I7L, a cysteine proteinase, and G1L, a putative metalloproteinase. These proteins are involved in the maturation of viral core proteins, p4a, p4b,...
Intimate partner violence is the systematic, intentional use of physical, emotional and/or sexual abuse that one person in a domestic relationship exerts over their partner in order to maintain power and control. In our society, we tend to focus on the external evidence of intimate partner violence such as the...
As genetically modified products come under greater production, tensions surrounding the potential benefits and harms of the technology have appeared in divergent policy between the European Union (EU) and certain member states. The purpose of this thesis is to consider whether some type of international law, also called an environmental...
Twenty seven modern (top 1-2cm) sediment samples from multicores retrieved from throughout coastal SE Alaska were analyzed for their organic matter content and the source composition. Total organic carbon (TOC) as well as biogenic silica (bioSi), and calcium carbonate (CaCO3) content were analyzed to evaluate the organic matter content and...
Rhodococcus fascians is a Gram-positive, pleiomorphic actinomycete that causes leafy gall formation in a wide range of plant hosts. This particular phytopathogen has been a focus of research at the Oregon State University Plant Clinic, a diagnostic laboratory. Phylogeny of R. fascians isolates obtained from Plant Clinic submissions was determined...
This study compares the accounting standards of three different entities, the United Kingdom Generally Accepted Accounting Principles, the domestic accounting standards of France, and the International Financial Reporting Standards (IFRS). The analysis consists of a comparison between two companies, British Airways and Air France – KLM, for FY 2005, specifically...
Mitochondria provide energy for biological cells to function, but this process is also a source of oxygen radicals that are capable of damaging nearby proteins. Mitochondrial protein damage can eventually lead to cell death, especially in the case of heart cells, where mitochondria are present in the highest concentrations. As...
This study was conducted to support a research project sponsored by the National Science Foundation (NSF). The purpose of the NSF research project was to determine how to design kaizen events that result in both short term and long term performance improvements. One of the tools developed to evaluate the...
The decisions in Solid Waste Agency of Northern Cook County v. U.S. Army Corps of Engineers, 531 U.S. 159 (2001) (SWANCC) and Rapanos v. United States, 547 U.S. ___(2006), deviated from the more broad interpretations of congressional intent granted by the court in past assessments of the constitutionality of environmental...
The debate over GM crops is one of the most controversial issues of recent decades. The debate has many dimensions, including environmental impacts, benefits and risks to human health, intellectual property rights, adequacy of biosafety regulations, and fundamental ethical acceptability. The potential benefits of GM crops are numerous, including improved...
We are developing a flavin-containing (Fmo) knock-out mouse for Fmo2 that will be utilized to elucidate the role of active human FMO isoform 2 (FMO2.1) in xenobiotic metabolism and toxicity. Since FMO2 is primarily expressed in lung this will provide information on how 27% of African-Americans and 5% of Hispanics...
America’s rural Hispanic population is growing at an unprecedented rate. Many of the Hispanic people that are settling in rural communities are immigrants or first generation Americans. If changes to current healthcare systems are required to accommodate the health needs of this growing, low-income rural population they have not been...
In the fall of 2005, I studied abroad in Athens, Greece for one term. This is retelling of experiences that I had, written in the style of my memories. While I was in Greece, I kept an electronic diary, a picture diary, and a scrapbook to keep my memories vivid...