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  • Generation of proof of concept molecules neutralizing monoclonal antibodies to IL17Cm

    Creator:
    Calhoun, Drew W.
    Abstract:
    Inflammation is one of the first, most important responses of the immune system when presented with infection and is mediated primarily by eicosanoids and cytokines. The goal of this research was to generate monoclonal antibodies against murine IL17C, a poorly characterized cytokine involved in inflammation and linked to inflammatory conditions....
    Resource Type:
    Honors College Thesis
    Full Text:
    THESIS OF Drew W. Calhoun for the degree of Honors Baccalaureate of Science in Biochemistry and

  • Investigating the age-related loss of endoplasmic reticulum stress response

    Creator:
    Fallahi, Anahita
    Abstract:
    The endoplasmic reticulum (ER) is a crucial organelle in the cell where protein folding and processing occurs, and conditions that negatively affect ER functions are highly detrimental to the cell. The accumulation of unfolded/misfolded proteins in the ER leads to a condition known as ER Stress. The ER has developed...
    Resource Type:
    Honors College Thesis
    Full Text:
    .) Wong W, Brotrom M. Inhibition of protein synthesis and early protein processing by thapsigargin in

  • The application of geographic information systems for delineation and classification of tidal wetlands for resource management of Oregon’s coastal watersheds

    Creator:
    Scranton, Russell W.
    Abstract:
    Resource managers of Oregon’s tidal wetlands require an improved GIS layer for management of existing tidal wetland habitat and areas considered for tidal wetland restoration. A reconnaissance project was initiated, such that interpretations of remote sensing data, the National Wetland Inventory, Oregon Estuary Plan Book and additional management tools were...
    Resource Type:
    Capstone Project
    Full Text:
    annually by 2005(DSL 2002). Also on April 22nd 2004, Earth Day, the George W. Bush administration adopted

  • Metaconversations : ongoing discussions about teaching research writing

    Creator:
    McMillen, Paula S. and Hill, Eric
    Abstract:
    This article is a follow up to an earlier publication that developed the rationale for using conversation as a metaphor to teach research writing. We presented this proposed teaching approach at several conferences, including WILU in May 2005 at Guelph, Canada. The discussions with participants in these presentations validated the...
    Resource Type:
    Article
    Full Text:
    successful research projects through collaboration. In P. Zemliansky, and Bishop, W. (Eds.), Research writing

  • A genomic and proteomic characterization of the first cultured oligotrophic marine Gammaproteobacterium from the SAR92 clade

    Creator:
    Mellbye, Brett L.
    Abstract:
    High-throughput culturing (HTC) consisting of extinction culturing in autoclaved seawater has led to the isolation and characterization of many novel strains of oligotrophic marine bacteria. Strain HTCC 2207 was isolated from the Oregon coast by the HTC method. Phylogenetic analysis based on 16S rRNA gene sequence showed that this strain...
    Resource Type:
    Honors College Thesis
    Full Text:
    thanks to Kevin Vergin, Sarah Sowell, Dr. Ulrich Stingl, and Jim Tripp for devoting so much of their time

  • Aging and oxidative damage to mitochondrial membrane proteins

    Creator:
    Tong, Tony T.
    Abstract:
    Mitochondria provide energy for biological cells to function, but this process is also a source of oxygen radicals that are capable of damaging nearby proteins. Mitochondrial protein damage can eventually lead to cell death, especially in the case of heart cells, where mitochondria are present in the highest concentrations. As...
    Resource Type:
    Honors College Thesis
    Full Text:
    bundle of appreciation goes out to Dr. Kevin Ahern. He has done so much for me and his many other

  • Exploring phylogeny of Rhodococcus fascians isolates using 16S ribosomal DNA sequence analysis

    Creator:
    Sandberg, Eva Song
    Abstract:
    Rhodococcus fascians is a Gram-positive, pleiomorphic actinomycete that causes leafy gall formation in a wide range of plant hosts. This particular phytopathogen has been a focus of research at the Oregon State University Plant Clinic, a diagnostic laboratory. Phylogeny of R. fascians isolates obtained from Plant Clinic submissions was determined...
    Resource Type:
    Honors College Thesis
    Full Text:
    Tzanetakis Dr. Aaron Liston Eric Hill Rebekah Lancelin Dr. Kevin Ahern Dr. Terri Fiez Molly Elliot

  • Pathogenic Mechanisms of Cancer Causing hMLH1 Mutations

    Creator:
    O'Donnell, Edmond Francis
    Abstract:
    DNA mismatch repair (MMR) is an evolutionary conserved process that functions to maintain genomic integrity through the correction of mismatches that have escaped proofreading. Mutations in the MMR gene Mlh1 are associated with approximately 50% of all cases of Lynch syndrome, a hereditary predisposition to colorectal cancer, through varying and...
    Resource Type:
    Honors College Thesis
    Full Text:
    collection, to Pete Hoffman for supplying the pRO1 plasmid construct, and to Kevin Ahern for his for his

  • Investigating the Role of the MutLα Endonuclease

    Creator:
    Mankaney, Gautam Naresh
    Abstract:
    Lynch individuals have a predisposition to developing colorectal and other cancers due to inherited defects in their mismatch repair (MMR) system. Although mutations in MMR have been directly implicated in Lynch Syndrome, the precise mechanism(s) of MMR functions have yet to be elucidated. One essential complex, MutL (a dimer of...
    Resource Type:
    Honors College Thesis
    Full Text:
    mothering me throughout my research experience, and Kevin Ahern for his advice and encouragement. Finally

  • The People's band: U2 and international activism

    Creator:
    Peterson, Maxie Jean
    Abstract:
    The end of the Cold War brought about changes within international political relations that resulted in expanded interest in global civil society. Such developments, like globalization and democratization, have encouraged the growth of social and political organizations. Political scientists have found that these inter-governmental and non-governmental organizations have a significant...
    Resource Type:
    Honors College Thesis