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Investigating the age-related loss of endoplasmic reticulum stress response

Creator:

Fallahi, Anahita

Abstract:

The endoplasmic reticulum (ER) is a crucial organelle in the cell where protein folding and processing occurs, and conditions that negatively affect ER functions are highly detrimental to the cell. The accumulation of unfolded/misfolded proteins in the ER leads to a condition known as ER Stress. The ER has developed...

Resource Type:

Honors College Thesis

Full Text:

and IRE1α (Bertollotti, 2000). The group led by Chen, et al, investigated the mechanism behind ATF6
Sexual dimorphism and seasonal changes in the Harderian gland of the red-sided garter snake, Thamnophis sirtalis parietalis

Creator:

Erickson, Sten M.

Abstract:

The Harderian gland (HG) of the red-sided garter snake, Thamnophis sirtalis parietalis, is a secretory structure that plays a role in the vomeronasal system by solubilizing semiochemicals such as prey chemoattractants and the female sexual attractiveness pheromone. The HG produces secretions containing pheromone-binding proteins that form a complex with pheromone...

Resource Type:

Honors College Thesis

Full Text:

garter snakes VN system (Halpern et al. 1987, Jiang et al. 1990, Wang et al. 1988). Earthworm Shock
Pathogenic Mechanisms of Cancer Causing hMLH1 Mutations

Creator:

O'Donnell, Edmond Francis

Abstract:

DNA mismatch repair (MMR) is an evolutionary conserved process that functions to maintain genomic integrity through the correction of mismatches that have escaped proofreading. Mutations in the MMR gene Mlh1 are associated with approximately 50% of all cases of Lynch syndrome, a hereditary predisposition to colorectal cancer, through varying and...

Resource Type:

Honors College Thesis