Index Catalog // ScholarsArchive@OSU

Targeted Nanocarriers for Systemic Delivery of IRAK4 Inhibitors to Inflamed Tissues

Creator:: Park, Youngrong, Korzun, Tetiana, Moses, Abraham S., Singh, Prem, Levasseur, Peter R., Demessie, Ananiya A., Sharma, Kongbrailatpam Shitaljit, Morgan, Terry, Raitmayr, Constanze J., Avila, Uriel, Sabei, Fahad Y., Taratula, Olena R., Marks, Daniel L., and Taratula, Oleh
Abstract:: Persistent and uncontrolled inflammation is the root cause of various debilitating diseases. Given that interleukin-1 receptor–associated kinase 4 (IRAK4) is a critical modulator of inflammation, inhibition of its activity with selective drug molecules (IRAK4 inhibitors) represents a promising therapeutic strategy for inflammatory disorders. To exploit the full potential of this...
Resource Type:: Article
Full Text:: , Peter R. Levasseur, Ananiya A. Demessie, Kongbrailatpam Shitaljit Sharma, Terry Morgan, Constanze J

Exploring Pactamycin Biosynthesis

Creator:: Roland, Jessica
Abstract:: Pactamycin, produced by the soil bacterium Streptomyces pactum, is a cytotoxic antibiotic that belongs to the aminocyclitol family of natural products. This antibiotic has shown various forms of biological activity, including antibacterial, antifungal, antimalarial, and antitumor activities. Despite its outstanding biological activity, the mode of formation of its pharmacophore (the...
Resource Type:: Honors College Thesis
Full Text:: into Escherichia coli BL21 pLysS. SDS-PAGE gel electrophoresis showed that the transformed E. coli

Injera in the Kapitalocene: Understanding Women’s Perceptions of Change in Mekelle, Ethiopia

Creator:: Arefaine, Micknai
Abstract:: Women’s lives in one of the oldest neighborhoods in Mekele, Ethiopia are very organized, systematic, and sophisticated. The women in this study model, express, and reflect the values of community, trust, care, stability, and futurity through their perceptions and sentiments regarding social and political change. I document how these values...
Resource Type:: Masters Thesis
Full Text:: appointed woman president, Sahle Work Zewde. Chapter 5, Selam ina Asphalt: Lucy’s story is that of

The Effects of UV Irradiation on the Biosorption of Titanium Dioxide Nanoparticles to Heterotrophic Biomass

Creator:: Young, William M.
Abstract:: The production of titanium dioxide (TiO2) nanoparticles has increased significantly in the past decades, which has generated concern due to their known toxicity in the environment. As a result of the production, use and disposal of productions containing TiO2, TiO2 nanoparticles are often received by wastewater treatment facilities. The adsorption...
Resource Type:: Honors College Thesis
Full Text:: , Nanoparticles, Wastewater, Ultraviolet, Biosorption Corresponding e-mail address: william.young2150@gmail.com

Assessing Exposures and Simplifying Complex Mixtures of SVOCs for Hazard Characterization using Alternative Model Systems

Creator:: Rivera, Brianna N.
Abstract:: Throughout their lifetime individuals are exposed to complex mixtures of chemicals. The study of chemical mixtures is an internationally recognized research priority, but seemingly complex challenge. To reduce the intricacy of studying mixtures, researchers have identified different prioritization methods based on exposure or the toxicity of chemicals. However, understanding the...
Resource Type:: Dissertation

Advancing Nanotechnology for Photoacoustic Imaging

Creator:: St Lorenz, Anna
Abstract:: Curbing overall disease burden with faster intervention requires early stage and accurate diagnostics. Ultrasound (US) provides a safe, nonionizing, inexpensive, and noninvasive imaging modality that has become commonplace in diagnostics. Paired with the relatively new technology of photoacoustic imaging (PAI), optical level resolution becomes feasible with the deeper signal penetration...
Resource Type:: Dissertation
Full Text:: , Dr. Fahad Sabei, Abraham Moses, Ananiya Demessie, Dr. Youngrong Park, Tetiana Korzun along with all

Studies on the ecological functions of the antidiabetic drugs acarbose

Creator:: Tanoeyadi, Samuel
Abstract:: Natural products (a.k.a. secondary metabolites) are produced by living organisms that are not essential for their growth, development, or reproduction, but may play a role in their survival or adaptability in nature. Many secondary metabolites isolated from plants and microbes have found use as molecular probes, drug leads, or medicine...
Resource Type:: Masters Thesis
Full Text:: ) Corresponding authors *E-mails: benjamin.philmus@oregonstate.edu and Taifo.Mahmud@oregonstate.edu Fax: (+1

Pushing the limits of graphite : the potential beyond conventional applications in aqueous dual-ion batteries

Creator:: Kim, Keun-il
Abstract:: The increase in the demand for energy is estimated to be 28 TW by a year of 2050, which is twice of the energy produced in 2010, in response to the unprecedented growth of the global population. Current energy market is heavily relying on the fossil fuel, which brings the...
Resource Type:: Dissertation
Full Text:: 20◦C (e) and 60◦C (f). Reprinted with permission from Ref 13. Copyright 2013, IOP Publishing

Development of Novel Therapeutic Approach for Ewing’s Sarcoma Treatment

Creator:: Sabei, Fahad Yahya
Abstract:: Ewing sarcoma (EwS) is the second most highly malignant tumor that arises mainly from bone and surrounding soft tissue of adolescent and young adult patients. Despite the advances in Ewing sarcoma treatment that today include a combination of five chemotherapeutic agents, surgery, and/or radiotherapy, these therapies have demonstrated limited improvement...
Resource Type:: Dissertation
Full Text:: Fatease, Canan Schumann, Ananiya Demessie, Tetiana Korzun, Abraham Moses, Anna St Lorenz, and Youngrong

ScholarsArchive@OSU

Targeted Nanocarriers for Systemic Delivery of IRAK4 Inhibitors to Inflamed Tissues

Exploring Pactamycin Biosynthesis

Injera in the Kapitalocene: Understanding Women’s Perceptions of Change in Mekelle, Ethiopia

The Effects of UV Irradiation on the Biosorption of Titanium Dioxide Nanoparticles to Heterotrophic Biomass

Assessing Exposures and Simplifying Complex Mixtures of SVOCs for Hazard Characterization using Alternative Model Systems

Advancing Nanotechnology for Photoacoustic Imaging

Studies on the ecological functions of the antidiabetic drugs acarbose

Pushing the limits of graphite : the potential beyond conventional applications in aqueous dual-ion batteries

Development of Novel Therapeutic Approach for Ewing’s Sarcoma Treatment

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