Natural products have long been an important source of resources for humans. Many of these compounds possess unique chemical structures and potent biological properties. By targeting natural products with specific chemical properties, we can gain a better understanding of the roles these compounds play in the environment and their interactions...
Background:
The number of people diagnosed with chronic physical conditions is increasing in the United States. Chronic mental illnesses are also common in the country. Low-income women and those on Medicaid bear a disproportionate burden of chronic conditions and these conditions significantly contribute to obstetric morbidity. Prioritizing preventive measures and...
One of the pervasive problems arising in our modern, digital world surrounds data breaches where an adversary, through zero-day exploitations, phishing, or old-fashioned social engineering attacks, gains access to a service’s data stores. Our society increasingly relies on these cloud-based services for everything from our taxes to personal communication. As...
Forests provide a wide range of timber and non-timber products along with providing a range of ecological services and support for biodiversity. Climate change poses various risks to forest health, as it can disrupt tree growth functions and trigger natural disturbances that increase tree mortality. In recent decades, altered disturbance...
Long-term, large-scale studies of meta-ecosystems provide critical information about how global change influences communities. In my dissertation, I analyzed data from studies encompassing 18 years (2006 – 2023) and over 1,000 km of coastline to investigate drivers of rocky intertidal community structure and dynamics. Specifically, I explored the roles of...
Optical sensing technologies are pivotal in the manufacturing process, specifically in defect detection, tool condition estimation, and monitoring. The research aims to enhance the accuracy, efficiency, and reliability of manufacturing metrology by employing optical sensing technologies, such as laser profilometers and image processing techniques. The dissertation proposes intelligent and flexible...
This dissertation examines college students' reflections on gender-related topics within a social justice course of a teacher preparation program. Using critical and feminist approaches, this study explores how a strategically designed curriculum focused on the study of gender enhances students' understanding of sexism, gender oppression, and masculinity. The curriculum employs...
The gut microbiome has been previously implemented in a number of diseases. Of note is its substantial role in metabolic syndrome, which encapsulates a group of conditions that increase the risk of cardiovascular disease, type 2 diabetes, and stroke. Understanding the causal relationships between the gut microbiome and host processes...
This work investigates the acoustic velocity of gas-liquid mixtures in vertical, co-current flow in a concentric annulus. Acoustic velocity shows promise as a detection parameter for the presence and amount of gas in a liquid flow because of its high sensitivity to gas void fraction in a gas-liquid mixture. However,...
Among the candidates for the next generation of nuclear power plant is the high temperature gas reactor (HTGR). Since the HTGR does not have the same operational history as water cooled reactors do in the United States, investigation into the response of different accident phenomena is still an active area...
In the most challenging nuclear power plant accidents, transient critical heat flux (CHF) is a primary phenomenon that drives peak cladding temperature and ultimately fuel failure. It is not yet determined whether the use of steady-state CHF methods can accurately predict transient CHF under the conditions of a blowdown due...
Metabolomics has recently gained momentum in biomolecule research and complements the genomics and proteomics research space. Metabolomics strives to detect, identify, and quantify all metabolites present in biological samples. In particular, biomolecular analysis using ultra-performance liquid chromatography combined with mass spectrometry (UPLC-MS) has become increasingly important for metabolomic analyses. Similarly,...
Professional school counselors are tasked with providing effective and relevant career counseling and career-focused activities with all K–12 students; however, the career domain remains the area where school counselors feel least efficacious and competent to broach as part of their role. Addressing the career domain in schools is vital as...
Rapid and sensitive detection of stress hormones, such as cortisol and dehydroepiandrosterone (DHEA), can benefit the diagnosis of diseases related to adrenal gland disorders, post-traumatic stress disorders, chronic fatigue syndrome, and more. Stress hormones fluctuate in a circadian rhythm, the highest in the early morning and the lowest at night;...
Learning to recognize objects is a fundamental and essential step in human perception and understanding of the world. Accordingly, research of object discovery across diverse modalities plays a pivotal role in the context of computer vision. This field not only contributes significantly to enhancing our understanding of visual information but...
Aromatic hydrocarbons represent a large class of environmental contaminants that have a broad range of structures, physicochemical properties, and toxicities. Arising from the burning of organic matter, particularly fossil fuels, they are both widespread and abundant in all environmental compartments. Both monoaromatic hydrocarbons (BTEX) and polycyclic aromatic hydrocarbons (PAHs) are...
Irritable bowel syndrome (IBS) is a prevalent gastrointestinal disorder experienced by 10–15% of the global population, manifesting as chronic abdominal pain, bloating and inconsistent bowel habits. The search for effective treatments remains ongoing. One promising contender in this realm is kappa-casein glycomacropeptide (GMP), a milk-derived peptide. Its potential benefits stem...
Cell signaling under external stimulation is a critical mechanism that governs many biological processes such as cell proliferation, cell migration, and cell apoptosis, etc. For multicellular organisms, the ability to synchronize heterogeneous individual cellular responses through intercellular communication is crucial to maintain normal functionality. However, even though the biological pathways...
Autonomous robotic agents are on their way to becoming in-home personal assistants, construction assistants, and warehouse workers. The degree of autonomy of such systems is reflected by the manner in which we specify goals to them; the abstraction of low-level commands to high-level goals goes hand-in-hand with increased autonomy. In...
Low-power receivers (RX) with 100$\mu W$-scale power consumption can enable several power/energy-constrained IoT applications. However, achieving sensitivity, interferer tolerance and wide operating range with low power presents a challenge for existing architectures, particularly those constrained to highly integrated solutions without high-Q off-chip components. Existing solutions rely heavily on high quality...