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Filtering by: Language English [eng] Remove constraint Language: English [eng] Subject Peptides Remove constraint Subject: Peptides

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The synthesis of β-alanyl peptides

Creator:

Sharkey, Hubert Joseph

Resource Type:

Dissertation
Ecology and applications of cutaneous mechanisms of resistance to amphibian chytridiomycosis

Creator:

Nebergall, Emily E.

Abstract:

Amphibian biodiversity is in rapid global decline, due in part to the fungal disease chytridiomycosis, caused by Batrachochytrium dendrobatidis (Bd). Susceptibility to Bd and chytridiomycosis varies between species and populations. Skin peptides and symbiotic skin bacteria appear to be important mechanisms of Bd resistance. However, not much is known about...

Resource Type:

Masters Thesis
Alkylation of peptides and proteins by S-(2-chloroethyl)glutathione and characterization of adducts by mass spectrometry

Creator:

Erve, John C. L.

Abstract:

Glutathione, a ubiquitous intracellular tripeptide, protects cells by reacting with electrophiles and radicals that can damage cellular macromolecules. However, glutathione conjugation is now recognized as one mechanism by which drugs and xenobiotics can also be converted to reactive intermediates having toxic consequences to cells. The halogenated alkane 1,2-dichloroethane forms S-(2-chloroethyl)...

Resource Type:

Dissertation
Synthesis and opioid activity of conformationally constrained dynorphin A analogues

Creator:

Arttamangkul, Seksiri

Resource Type:

Dissertation
Polyion sensors based on induced ion extraction

Creator:

Fordyce, Katherine

Abstract:

A novel method for detecting the peptidase activity of clinically relevant peptidases was investigated using solid-contact electrochemical polyion sensors under chronopotentiometric control. Complete instrumental control over ion-extraction was accomplished by incorporating a lipophilic electrolyte into the ion-selective membrane; the sensors had no intrinsic ion-exchange capabilities. The sensors were used to...

Resource Type:

Masters Thesis
Gas-phase fragmentation chemistry of protonated peptide ions

Creator:

Bythell, Benjamin James

Abstract:

The fragmentation characteristics of protonated peptides have been investigated using tandem mass spectrometry (MS/MS) under various fragmentation regimes and detailed density functional theory (DFT) reaction pathway calculations. The DFT calculations predict novel salt-bridge stabilized transition structures as well as consecutive reactions occurring in proton-bound dimers for some of the ions...

Resource Type:

Dissertation
Electron molecule interactions of amino acids and peptides

Creator:

Figard, Benjamin J.

Abstract:

Electron-biomolecule interactions are a biologically relevant field of study because there are several ion fragmentation techniques that have come to the forefront in mass spectrometric analysis that involve the interaction of charged peptides and free electrons. By studying the electron energies that cause fragmentation in neutral amino acids, amino acid...

Resource Type:

Dissertation

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Academic Affiliation

Chemistry3
Biochemistry and Biophysics1
College of Pharmacy1
Microbiology1

Advisor

Adams, Michael1
Aldrich, Jane V.1
Barofsky, Douglas F.1
Bartholomew, Jerri L.1
Cheldelin, Vernon H.1
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Commencement Year

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Current results range from 1956 to 2014

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Committee Member

Barofsky, Douglas1
Barofsky, Douglas F.1
Buhler, Donald R.1
Deinzer, Max1
Field, Kate1
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Creator

Arttamangkul, Seksiri1
Bythell, Benjamin James1
Erve, John C. L.1
Figard, Benjamin J.1
Fordyce, Katherine1
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Date

Date range begin – Date range end

Current results range from 1956 to 2013

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Decade

2010-20191
2000-20093
1990-19992
1950-19591

Degree Field

Chemistry3
Biochemistry and Biophysics1
Microbiology1
Pharmacy1
Toxicology1

Degree Level

Doctoral5
Master's2

Degree Name

Doctor of Philosophy (Ph.D.)5
Master of Science (M.S.)2

File Format

application/pdf2

Language

English [eng][remove]7

License

All rights reserved4

Non-Academic Affiliation

Oregon State University. Graduate School7

Peer Reviewed

No6

Resource Type

Dissertation5
Masters Thesis2

Rights Statement

In Copyright4
Copyright Not Evaluated3

Subject

Peptides[remove]7
Alkylation1
Amino acids1
Amphibian declines1
Batrachochytrium dendrobatidis1
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