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A metabolic function of selenium, assessed with rat liver homogenates

Creator:: Bull, Richard Charles
Abstract:: In three separate trials rats were fed either a basal diet deficient in selenium and vitamin E or the same diet supplemented with one or both of these factors. In addition to these treatments in two of the trials, ethoxyquin was included to provide adequate lipid antioxidant protection and to...
Resource Type:: Dissertation
Full Text:: beneficial effect upon reproduction in the rat. Somewhat later Poley et al. (1941), also conducting a

Influence of dietary selenium on the distribution of tritium-labeled vitamin E in the rate

Creator:: Cheeke, Peter R.
Abstract:: A series of four trials were conducted to determine the influence of selenium supplementation of a selenium- and vitamin E-deficient basal diet on the absorption, excretion, tissue distribution and placental transfer of a single dose of tritium-labeled α-tocopherol in the rat. In the first trial, the effect of supplementation of...
Resource Type:: Dissertation
Full Text:: the rat. In the first trial, the effect of supplementation of the basal diet with 1. 0 ppm selenium

Histologic effects of chronic selenium deficiency in selected tissues of laboratory rats

Creator:: Sprinker, Lucas Harry
Abstract:: The selenium-responsive syndromes and the discovery of Factor 3-selenium focused attention on selenium in metabolism. Two hypotheses have been advanced to explain the metabolic effect of selenium: 1) substitution or sparing of alpha tocopherol, and 2) a primary role in metabolism. The first hypothesis is supported by Scott and Desai,...
Resource Type:: Masters Thesis
Full Text:: metabolic effect of selenium: 1) substitution or sparing of alpha tocopherol, and 2) a primary role in

The effect of selenium on chemical carcinogenicity in the rat

Creator:: Johnston, Weldon Kearney
Abstract:: One hundred and fifty-one weanling rats of both sexes were fed control diets or diets containing 160 ppm diethylnitrosamine (DEN) or 150 ppm N-2-fluorenyl-acetamide (FAA). The carcinogen level was calculated so that the LD₅₀ should be achieved at about 17 weeks. Each carcinogen treatment was incorporated with three different diet...
Resource Type:: Masters Thesis
Full Text:: The Effect of Selenium on Chemical Carcinogenicity in the

The effect of selenium deficiency on the fatty acid metabolism of rats and lambs

Creator:: Fischer, William Carl
Abstract:: Selenium deficiency in rats results in increased carbon metabolism, approaching twice the rate of selenium supplemented animals (normal). This is also reflected in a 50 percent increase in lysosomal enzyme activity in tissues of selenium deficient animals. Isolation of rat liver lysosomes shows a 17 percent increase in membrane thickness...
Resource Type:: Dissertation
Full Text:: , 1974 (Major Department) Title: THE EFFECT OF SELENIUM DEFICIENCY ON THE FATTY ACID METABOLISM OF RATS

Selenium effects and species differences in hepatic metabolism of pyrrolizidine alkaloids and other xenobiotics

Creator:: Shull, Lee R.
Abstract:: The metabolism of pyrrolizidine alkaloids and other drugs was studied with regard to nutritional status and species differences. Pyrrolizidine alkaloids which are biotransformed to severely toxic metabolites were isolated from tansy ragwort (Senecio jacobaea). Semi-purified alkaloid crystals containing five alkaloids (senecionine, seneciophylline, jacobine, jacoline, and jacozine) were prepared and found...
Resource Type:: Dissertation
Full Text:: liver weight, but had no effect on microsomal oxidases. Similarly, high copper had no effect on the

Some possible roles for selenium in the reproductive physiology of the male graytailed vole (Microtus canicaudus)

Creator:: Whitfield, Stephen Curtiss
Abstract:: The testes of the gray-tailed vole (Microtus canicaudus Miller) exhibited a high affinity for selenium relative to other selected tissues. Uptake of selenium-75 in the testis-epididymis complex was delayed relative to uptake by the whole body, kidney, and liver. This pattern of uptake suggested that selenium was metabolically incorporated into...
Resource Type:: Masters Thesis
Full Text:: E in the diet, the addition of selenium produced no significant changes in measured physiological

Selenium-75 incorporation in semen and reproductive organs of the bull and ram

Creator:: Pond, Finn Richard
Resource Type:: Dissertation

The influence of selenium on selenoprotein W

Creator:: Yeh, Jan-ying
Abstract:: The objective of our study was to investigate the effect of selenium on selenoprotein W. Western blot analysis indicated that selenoprotein W is present in muscle, brain, testis and spleen of rat tissues. Tissue distribution of selenoprotein W was not altered in rats fed various selenium levels. Among muscle, brain,...
Resource Type:: Dissertation
Full Text:: . Whanger The objective of our study was to investigate the effect of selenium on selenoprotein W

The effect of food processing on the bioavailability of selenium in tuna and wheat : human and rat studies

Creator:: Alexander, Anne Rose
Abstract:: Bioavailability of selenium (Se) in processed tuna and wheat products was studied in humans and rats. The protein source of the rat diets was torula yeast with Se supplied by either raw, precooked or canned tuna, or whole wheat flour, bread or bran. Sodium selenite was used as a control....
Resource Type:: Dissertation
Full Text:: of Doctor of Philosophy in Poods and Nutrition presented on January 22, 1982 Title: The Effect of

ScholarsArchive@OSU

A metabolic function of selenium, assessed with rat liver homogenates

Influence of dietary selenium on the distribution of tritium-labeled vitamin E in the rate

Histologic effects of chronic selenium deficiency in selected tissues of laboratory rats

The effect of selenium on chemical carcinogenicity in the rat

The effect of selenium deficiency on the fatty acid metabolism of rats and lambs

Selenium effects and species differences in hepatic metabolism of pyrrolizidine alkaloids and other xenobiotics

Some possible roles for selenium in the reproductive physiology of the male graytailed vole (Microtus canicaudus)

Selenium-75 incorporation in semen and reproductive organs of the bull and ram

The influence of selenium on selenoprotein W

The effect of food processing on the bioavailability of selenium in tuna and wheat : human and rat studies

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