Index Catalog // ScholarsArchive@OSU

A study of the effects of an extended transfer student orientation course on factors of student success

Creator:: Corley, Sherie P.
Abstract:: Transfer students often experience difficulties in adjusting to a new institutional environment, and these difficulties may limit their academic potential. Success predictors identified in research may not be part of their experiences. Can an institution create a formal process which can ameliorate deficiencies within success factors for transfer students? This...
Resource Type:: Dissertation

Preliminary physiologically based pharmacokinetic models for benzo[a]pyrene and dibenzo[def,p]chrysene in rodents

Creator:: Crowell, Susan Ritger, Amin, Shantu G., Anderson, Kim A., Krishnegowda, Gowdahalli, Sharma, Arun K., Soelberg, Jolen J., Williams, David E., and Corley, Richard A.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants generated as byproducts of natural and anthropogenic combustion processes. Despite significant public health concern, physiologically based pharmacokinetic (PBPK) modeling efforts for PAHs have so far been limited to naphthalene, plus simpler PK models for pyrene, nitropyrene, and benzo[a]pyrene (B[a]P). The dearth of...
Resource Type:: Article
Full Text:: physiologically based pharmacokinetic models for benzo[a]pyrene and dibenzo[def,p]chrysene in rodents Toxicology

Transplacental Carcinogenesis with Dibenzo[def,p]chrysene (DBC): Timing of Maternal Exposures Determines Target Tissue Response in Offspring

Creator:: Shorey, Lyndsey, Castro, David J., Baird, William, Siddens, Beth, Lohr, Christiane, Matzke, Melissa, Waters, Katrina M., Corley, Richard A., and Williams, David E.
Abstract:: Dibenzo[def,p]chrysene (DBC) is a transplacental carcinogen in mice (15 mg/kg; gestation day (GD) 17). To mimic residual exposure throughout pregnancy, dams received 4 smaller doses of DBC (3.75 mg/kg) on GD 5, 9, 13 and 17. This regimen alleviated the previously established carcinogenic responses in the thymus, lung, and liver....
Resource Type:: Article
Full Text:: track changes.doc 1 Transplacental Carcinogenesis with Dibenzo[def,p]chrysene (DBC): Timing of

Human in vivo Pharmacokinetics of [¹⁴C]Dibenzo[def,p]chrysene by Accelerator Mass Spectrometry Following Oral Micro-Dosing

Creator:: Madeen, Erin, Corley, Richard A., Crowell, Susan, Turteltaub, Kenneth, Ognibene, Ted, Malfatti, Mike, McQuistan, Tammie J., Garrard, Mary, Sudakin, Dan, and Williams, David E.
Abstract:: Dibenzo(def,p)chrysene (DBC), (also known as dibenzo[a,l]pyrene), is a high molecular weight polycyclic aromatic hydrocarbon (PAH) found in the environment, including food, produced by the incomplete combustion of hydrocarbons. DBC, classified by IARC as a 2A probable human carcinogen, has a relative potency factor (RPF) in animal cancer models 30-fold higher...
Resource Type:: Article

Measuring Anti-Müllerian Hormone Concentrations to Determine Reproductive Status in Female Rabbits

Creator:: Meeker, Alissa R.
Abstract:: There are over two million pet rabbits in the United States. Many rabbits are obtained as adults from pet stores and humane societies. Pet rabbit owners may elect to perform ovariohysterectomy (spay) surgeries on female rabbits to prevent unwanted pregnancies as well as to eliminate the possibility of reproductive disorders...
Resource Type:: Honors College Thesis
Full Text:: were combined to create a positive pool (+P); the remaining sera from spayed rabbits were combined to

Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework

Creator:: Teeguarden, Justin G., Tan, Yu-Mei, Edwards, Stephen W., Leonard, Jeremy A., Anderson, Kim A., Corley, Richard A., Kile, Molly L., Simonich, Staci M., Stone, David, Tanguay, Robert L., Waters, Katrina M., Harper, Stacey L., and Williams, David E.
Abstract:: Driven by major scientific advances in analytical methods, biomonitoring, computation, and a newly articulated vision for a greater impact in public health, the field of exposure science is undergoing a rapid transition from a field of observation to a field of prediction. Deployment of an organizational and predictive framework for...
Resource Type:: Article
Full Text:: ,‡ Richard A. Corley,‡,† Molly L. Kile,§ Staci M. Simonich,‡ David Stone,‡ Robert L. Tanguay,‡ Katrina M

Sulforaphane Regulation of LncRNA in a Transplacental Nrf2 Knockout Mouse Model Exposed to Dibenzo[def,p]chrysene

Creator:: Patel, Karan A.
Abstract:: Dibenzo[def,p]chrysene (DBC) is a highly potent, but less prevalent, environmental carcinogen belonging to a class of compounds known as Polycyclic Aromatic Hydrocarbons (PAHs). They are highly ubiquitous and arise as a byproduct of natural and anthropogenic combustion processes. Previous studies have documented carcinogenic effects upon in utero exposure of PAHs....
Resource Type:: Honors College Thesis
Full Text:: Regulation of LncRNA in a Transplacental Nrf2 Knockout Mouse Model Exposed to Dibenzo[def,p]chrysene

Translational Studies of the High Molecular Weight Polycyclic Aromatic Hydrocarbon, Dibenzo[ def,p] Chrysene; Carcinogenesis and Metabolism

Creator:: Madeen, Erin
Abstract:: The objective of this work is to add to the body of translational data between high dose animal model research and the environmentally relevant human metabolism of the persistent pollutant dibenzo[def,p]chrysene (DBC). We furthered the knowledge of gene/exposure interactions by determining the carcinogenesis risk based on Cyp1b1 genotype following in...
Resource Type:: Dissertation
Full Text:: Aromatic Hydrocarbon, Dibenzo[def,p] Chrysene; Carcinogenesis and Metabolism Abstract approved

Evaluation of collaborative filtering and content based filtering recommenders in jTutors (an online intelligent tutoring system)

Creator:: Appasamy, Bharatwaj
Abstract:: Software engineers often need help with discovering and learning how to use APIs. For example, software engineers who are starting to learn Java, and they want to implement a certain feature in a program, they might want to reuse existing APIs in order to save time versus rewriting it themselves...
Resource Type:: Masters Thesis
Full Text:: : ______________________________________________________ Christopher P. Scaffidi Software engineers often need help with discovering and learning

The effects of various levels of dietary protein on high producing dairy cows in early lactation

Creator:: Pangborn, Marvin Clark
Abstract:: This project was designed to test the biological effects of three levels of dietary protein (12.7, 16.3 and 19.3% CP on a dry matter basis) on high producing Holstein-Friesian dairy cows. Forty five second lactation or older cows that showed the potential to produce over 31.75 kg (70 lbs) per...
Resource Type:: Masters Thesis
Full Text:: three (61-90 days). Milk fat % was greater (P < .01) for period one. Milk protein was not

ScholarsArchive@OSU

A study of the effects of an extended transfer student orientation course on factors of student success

Preliminary physiologically based pharmacokinetic models for benzo[a]pyrene and dibenzo[def,p]chrysene in rodents

Transplacental Carcinogenesis with Dibenzo[def,p]chrysene (DBC): Timing of Maternal Exposures Determines Target Tissue Response in Offspring

Human in vivo Pharmacokinetics of [¹⁴C]Dibenzo[def,p]chrysene by Accelerator Mass Spectrometry Following Oral Micro-Dosing

Measuring Anti-Müllerian Hormone Concentrations to Determine Reproductive Status in Female Rabbits

Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework

Sulforaphane Regulation of LncRNA in a Transplacental Nrf2 Knockout Mouse Model Exposed to Dibenzo[def,p]chrysene

Translational Studies of the High Molecular Weight Polycyclic Aromatic Hydrocarbon, Dibenzo[ def,p] Chrysene; Carcinogenesis and Metabolism

Evaluation of collaborative filtering and content based filtering recommenders in jTutors (an online intelligent tutoring system)

The effects of various levels of dietary protein on high producing dairy cows in early lactation

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