Index Catalog // ScholarsArchive@OSU

Astragaloside IV Inhibits NF-κB Activation and Inflammatory Gene Expression in LPS-Treated Mice

Creator:: Zhang, Wei-Jian and Frei, Balz
Abstract:: In this study we investigated the role of astragaloside IV (AS-IV), one of the major active constituents purified from the Chinese medicinal herb Astragalus membranaceus, in LPS-induced acute inflammatory responses in mice in vivo and examined possible underlying mechanisms. Mice were assigned to four groups: vehicle-treated control animals; AS-IV-treated animals...
Resource Type:: Article
Full Text:: . 8, no. 10, Article ID e76495, 2013. [41] Q. Zhang, L.-L. Zhu, G.-G. Chen, andY. Du

Combined treatment of rapamycin and dietary restriction has a larger effect on the transcriptome and metabolome of liver

Creator:: Fok, Wilson C., Bokov, Alex, Gelfond, Jonathan, Yu, Zhen, Zhang, Yiqiang, Doderer, Mark, Chen, Yidong, Javors, Martin, Wood, William H., III, Zhang, Yongqing, Becker, Kevin G., Richardson, Arlan, and Pérez, Viviana I.
Abstract:: Rapamycin (Rapa) and dietary restriction (DR) have consistently been shown to increase lifespan. To investigate whether Rapa and DR affect similar pathways in mice, we compared the effects of feeding mice ad libitum (AL), Rapa, DR, or a combination of Rapa and DR (Rapa + DR) on the transcriptome and...
Resource Type:: Article

Selective Ablation of Ctip2/Bcl11b in Epidermal Keratinocytes Triggers Atopic Dermatitis-Like Skin Inflammatory Responses in Adult Mice

Creator:: Wang, Zhixing, Zhang, Ling-juan, Guha, Gunjan, Li, Shan, Kyrylkova, Kateryna, Kioussi, Chrissa, Leid, Mark, Ganguli-Indra, Gitali, and Indra, Arup K.
Abstract:: Background: Ctip2 is crucial for epidermal homeostasis and protective barrier formation in developing mouse embryos. Selective ablation of Ctip2 in epidermis leads to increased transepidermal water loss (TEWL), impaired epidermal proliferation, terminal differentiation, as well as altered lipid composition during development. However, little is known about the role of Ctip2...
Resource Type:: Article
Full Text:: , Zhang L-j, Guha G, Li S, Kyrylkova K, et al. (2012) Selective Ablation of Ctip2/Bcl11b in Epidermal

The ERI-6/7 Helicase Acts at the First Stage of an siRNA Amplification Pathway That Targets Recent Gene Duplications

Creator:: Fischer, Sylvia E. J., Montgomery, Taiowa A., Zhang, Chi, Fahlgren, Noah, Breen, Peter C., Hwang, Alexia, Sullivan, Christopher M., Carrington, James C., and Ruvkun, Gary
Abstract:: Endogenous small interfering RNAs (siRNAs) are a class of naturally occuring regulatory RNAs found in fungi, plants, and animals. Some endogenous siRNAs are required to silence transposons or function in chromosome segregation; however, the specific roles of most endogenous siRNAs are unclear. The helicase gene eri-6/7 was identified in the...
Resource Type:: Article
Full Text:: siRNA maturation. Citation: Fischer SEJ, Montgomery TA, Zhang C, Fahlgren N, Breen PC, et al. (2011

Evaluating the agreement between measurements and models of net ecosystem exchange at different times and timescales using wavelet coherence: an example using data from the North American Carbon Program Site-Level Interim Synthesis

Creator:: Stoy, P. C., Dietze, M. C., Richardson, A. D., Vargas, R., Barr, A. G., Anderson, R. S., Arain, M. A., Baker, Ian T., Black, T. Andrew, Chen, J. M., Cook, R. B., Gough, C. M., Grant, R. F., Hollinger, D. Y., Izaurralde, R. C., Kucharik, C. J., Lafleur, P., Law, B. E., Liu, S., Lokupitiya, E., Luo, Y., Munger, J. W., Peng, C., Poulter, B., Price, D. T., Ricciuto, D. M., Riley, W. J., Sahoo, A. K., Schaefer, K., Schwalm, C. R., Tian, H., Verbeeck, H., and Weng, E.
Abstract:: Earth system processes exhibit complex patterns across time, as do the models that seek to replicate these processes. Model output may or may not be significantly related to observations at different times and on different frequencies. Conventional model diagnostics provide an aggregate view of model–data agreement, but usually do not...
Resource Type:: Article

An update to the Surface Ocean CO₂ Atlas (SOCAT version 2)

Creator:: Bakker, D. C. E., Pfeil, B., Smith, K., Hankin, S., Olsen, A., Alin, S. R., Cosca, C., Harasawa, S., Kozyr, A., Nojiri, Y., O'Brien, K. M., Schuster, U., Telszewski, M., Tilbrook, B., Wada, C., Akl, J., Barbero, L., Bates, N. R., Boutin, J., Bozec, Y., Cai, W.-J., Castle, R. D., Chavez, F. P., Chen, L., Chierici, M., Currie, K., de Baar, H. J. W., Evans, W., Feely, R. A., Fransson, A., Gao, Z., Hales, B., Hardman-Mountford, N. J., Hoppema, M., Huang, W.-J., Hunt, C. W., Huss, B., Ichikawa, T., Johannessen, T., Jones, E. M., Jones, S. D., Jutterström, S., Kitidis, V., Körtzinger, A., Landschützer, P., Lauvset, S. K., Lefèvre, N., Manke, A. B., Mathis, J. T., Merlivat, L., Metzl, N., Murata, A., Newberger, T., Omar, A. M., Ono, T., Park, G.-H., Paterson, K., Pierrot, D., Ríos, A. F., Sabine, C. L., Saito, S., Salisbury, J., Sarma, V. V. S. S., Schlitzer, R., Sieger, R., Skjelvan, I., Steinhoff, T., Sullivan, K. F., Sun, H., Sutton, A. J., Suzuki, T., Sweeney, C., Takahashi, T., Tjiputra, J., Tsurushima, N., van Heuven, S. M. A. C., Vandemark, D., Vlahos, P., Wallace, D. W. R., Wanninkhof, R., and Watson, A. J.
Abstract:: The Surface Ocean CO2 Atlas (SOCAT), an activity of the international marine carbon research community, provides access to synthesis and gridded fCO2 (fugacity of carbon dioxide) products for the surface oceans. Version 2 of SOCAT is an update of the previous release (version 1) with more data (increased from 6.3...
Resource Type:: Article

Differential surface activation of the A1 domain of von Willebrand factor

Creator:: Tronic, Elaine H., Yakovenko, Olga, Weidner, Tobias, Baio, Joe E., Penkala, Rebecca, Castner, David G., and Thomas, Wendy E.
Abstract:: The clotting protein von Willebrand factor (VWF) binds to platelet receptor glycoprotein Ibα (GPIbα) when VWF is activated by chemicals, high shear stress, or immobilization onto surfaces. Activation of VWF by surface immobilization is an important problem in the failure of cardiovascular implants, but is poorly understood. Here, the authors...
Resource Type:: Article
Full Text:: , 729 (2010). 32C. Y. Song, W. L. Chen, M. C. Yang, J. P. Huang, and S. J. T. Mao, J. Biol. Chem. 280

Performance of Linear and Nonlinear Two-Leaf Light Use Efficiency Models at Different Temporal Scales

Creator:: Wu, Xiaocui, Ju, Weimin, Zhou, Yanlian, He, Mingzhu, Law, Beverly E., Black, T. Andrew, Margolis, Hank A., Cescatti, Alessandro, Gu, Lianhong, Montagnani, Leonardo, Noormets, Asko, Griffis, Timothy J., Pilegaard, Kim, Varlagin, Andrej, Valentini, Riccardo, Blanken, Peter D., Wang, Shaoqiang, Wang, Huimin, Han, Shijie, Yan, Junhua, Li, Yingnian, Zhou, Bingbing, and Liu, Yibo
Abstract:: The reliable simulation of gross primary productivity (GPP) at various spatial and temporal scales is of significance to quantifying the net exchange of carbon between terrestrial ecosystems and the atmosphere. This study aimed to verify the ability of a nonlinear two-leaf model (TL-LUEn), a linear two-leaf model (TL-LUE), and a...
Resource Type:: Article
Full Text:: fraction (22%) of incident direct PAR. Recently, Zhang et al. [21] reported that canopy LUE generally

Genetic Susceptible Locus in NOTCH2 Interacts with Arsenic in Drinking Water on Risk of Type 2 Diabetes

Creator:: Pan, Wen-Chi, Kile, Molly L., Seow, Wei Jie, Lin, Xihong, Quamruzzaman, Quazi, Rahman, Mahmuder, Mahiuddin, Golam, Mostofa, Golam, Lu, Quan, and Christiani, David C.
Abstract:: Abstract: Background: Chronic exposure to arsenic in drinking water is associated with increased risk of type 2 diabetes mellitus (T2DM) but the underlying molecular mechanism remains unclear. Objectives: This study evaluated the interaction between single nucleotide polymorphisms (SNPs) in genes associated with diabetes and arsenic exposure in drinking water on...
Resource Type:: Article
Full Text:: : UNICEF. 9. Lai MS, Hsueh YM, Chen CJ, Shyu MP, Chen SY, et al. (1994) Ingested inorganic arsenic and

Catalyst selective and regiodivergent O- to C- or N-carboxyl transfer of pyrazolyl carbonates: synthetic and computational studies

Creator:: Gould, Eoin, Walden, Daniel M., Kasten, Kevin, Johnston, Ryne C., Wu, Jiufeng, Slawin, Alexandra M., Mustard, Thomas J. L., Johnston, Brittany, Davies, Tony, Cheong, Paul Ha-Yeon, and Smith, Andrew D.
Abstract:: The regiodivergent O- to C- or N-carboxyl transfer of pyrazolyl carbonates is described, with DMAP giving preferential N-carboxylation and triazolinylidenes promoting selective C-carboxylation (both with up to >99 : 1 regioselectivity). An enantioselective O- to C-carboxyl variant using NHC catalysis is demonstrated (up to 92% ee), while mechanistic and DFT studies outline...
Resource Type:: Article
Full Text:: . Chen, Z.-J. Wu, X.-L. Du, L.-F. Cun, X.-M. Zhang and W.-C. Yuan, Adv. Synth. Catal., 2010, 352, 827–832

ScholarsArchive@OSU

Astragaloside IV Inhibits NF-κB Activation and Inflammatory Gene Expression in LPS-Treated Mice

Combined treatment of rapamycin and dietary restriction has a larger effect on the transcriptome and metabolome of liver

Selective Ablation of Ctip2/Bcl11b in Epidermal Keratinocytes Triggers Atopic Dermatitis-Like Skin Inflammatory Responses in Adult Mice

The ERI-6/7 Helicase Acts at the First Stage of an siRNA Amplification Pathway That Targets Recent Gene Duplications

Evaluating the agreement between measurements and models of net ecosystem exchange at different times and timescales using wavelet coherence: an example using data from the North American Carbon Program Site-Level Interim Synthesis

An update to the Surface Ocean CO₂ Atlas (SOCAT version 2)

Differential surface activation of the A1 domain of von Willebrand factor

Performance of Linear and Nonlinear Two-Leaf Light Use Efficiency Models at Different Temporal Scales

Genetic Susceptible Locus in NOTCH2 Interacts with Arsenic in Drinking Water on Risk of Type 2 Diabetes

Catalyst selective and regiodivergent O- to C- or N-carboxyl transfer of pyrazolyl carbonates: synthetic and computational studies

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