Index Catalog // ScholarsArchive@OSU

Article Deposit Services in Support of Federal Agency Public Access Requirements

Creator:: Boock, Michael, Zhang, Hui, and Clark, Erin
Abstract:: INTRODUCTION: Academic libraries have experimented with a variety of services to encourage article deposit to institutional repositories, with varying degrees of success. Universities now face the challenge of meeting federal agency public access requirements. Following the White House Office of Science Technology and Policy public access directive in 2013, Oregon...
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Full Text:: STEPS As a result, the library is now working with the university office of research to promote a

Water, Water, Everywhere: Defining and Assessing Data Sharing in Academia

Creator:: Van Tuyl, Steven and Whitmire, Amanda L.
Abstract:: Sharing of research data has begun to gain traction in many areas of the sciences in the past few years because of changing expectations from the scientific community, funding agencies, and academic journals. National Science Foundation (NSF) requirements for a data management plan (DMP) went into effect in 2011, with...
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Full Text:: in Academia RESEARCH ARTICLE Water, Water, Everywhere: Defining and Assessing Data Sharing in

Host species composition influences infection severity among amphibians in the absence of spillover transmission

Creator:: Han, Barbara A., Kerby, Jacob L., Searle, Catherine L., Storfer, Andrew, and Blaustein, Andrew R.
Abstract:: Wildlife epidemiological outcomes can depend strongly on the composition of an ecological community, particularly when multiple host species are affected by the same pathogen. However, the relationship between host species richness and disease risk can vary with community context and with the degree of spillover transmission that occurs among co-occurring...
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Triclosan Exposure Is Associated with Rapid Restructuring of the Microbiome in Adult Zebrafish

Creator:: Gaulke, Christopher A., Barton, Carrie L., Proffitt, Sarah, Tanguay, Robert L., and Sharpton, Thomas J.
Abstract:: Growing evidence indicates that disrupting the microbial community that comprises the intestinal tract, known as the gut microbiome, can contribute to the development or severity of disease. As a result, it is important to discern the agents responsible for microbiome disruption. While animals are frequently exposed to a diverse array...
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¹⁸O-Tracer Metabolomics Reveals Protein Turnover and CDP-Choline Cycle Activity in Differentiating 3T3-L1 Pre-Adipocytes

Creator:: Kirkwood, Jay S., Miranda, Cristobal L., Bobe, Gerd, Maier, Claudia S., and Stevens, Jan F.
Abstract:: The differentiation of precursor cells into mature adipocytes (adipogenesis) has been an area of increased focus, spurred by a rise in obesity rates. Though our understanding of adipogenesis and its regulation at the cellular level is growing, many questions remain, especially regarding the regulation of the metabolome. The 3T3-L1 cell...
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Rapid Synthesis of a Long Double-Stranded Oligonucleotide from a Single-Stranded Nucleotide Using Magnetic Beads and an Oligo Library

Creator:: Pengpumkiat, Sumate, Koesdjojo, Myra, Rowley, Erik R., Mockler, Todd C., and Remcho, Vincent T.
Abstract:: Chemical synthesis of oligonucleotides is a widely used tool in the field of biochemistry. Several methods for gene synthesis have been introduced in the growing area of genomics. In this paper, a novel method of constructing dsDNA is proposed. Short (28-mer) oligo fragments from a library were assembled through successive...
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Patterns and Variation in Benthic Biodiversity in a Large Marine Ecosystem

Creator:: Piacenza, Susan E., Barner, Allison K., Benkwitt, Cassandra E., Boersma, Kate S., Cerny-Chipman, Elizabeth B., Ingeman, Kurt E., Kindinger, Tye L., Lee, Jonathan D., Lindsley, Amy J., Reimer, Jessica N., Rowe, Jennifer C., Shen, Chenchen, Thompson, Kevin A., Thurman, Lindsey L., and Heppell, Selina S.
Abstract:: While there is a persistent inverse relationship between latitude and species diversity across many taxa and ecosystems, deviations from this norm offer an opportunity to understand the conditions that contribute to large-scale diversity patterns. Marine systems, in particular, provide such an opportunity, as marine diversity does not always follow a...
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Full Text:: /journal.pone.0135135 Public Library of Science Version of Record http://cdss.library.oregonstate.edu/sa

Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease

Creator:: Punj, Sumit, Kopparapu, Prasad, Jang, Hyo Sang, Phillips, Jessica L., Pennington, Jamie, Rohlman, Diana, O'Donnell, Edmond, Iversen, Patrick L., Kolluri, Siva Kumar, and Kerkvliet, Nancy I.
Abstract:: The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that plays multiple roles in regulation of immune and inflammatory responses. The ability of certain AhR ligands to induce regulatory T cells (Tregs) has generated interest in developing AhR ligands for therapeutic treatment of immune-mediated diseases. To this end, we...
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Formation of Complexes at Plasmodesmata for Potyvirus Intercellular Movement Is Mediated by the Viral Protein P3N-PIPO

Creator:: Wei, Taiyun, Zhang, Changwei, Hong, Jian, Xiong, Ruyi, Kasschau, Krisitin D., Zhou, Xueping, Carrington, James C., and Wang, Aiming
Abstract:: Intercellular transport of viruses through cytoplasmic connections, termed plasmodesmata (PD), is essential for systemic infection in plants by viruses. Previous genetic and ultrastructural data revealed that the potyvirus cyclindrical inclusion (CI) protein is directly involved in cell-to-cell movement, likely through the formation of conical structures anchored to and extended through...
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Full Text:: Wang1,2* 1 Southern Crop Protection and Food Research Centre, Agriculture and Agri-Food Canada, London

Perchlorate Exposure Reduces Primordial Germ Cell Number in Female Threespine Stickleback

Creator:: Petersen, Ann M., Earp, Nathanial C., Redmond, Mandy E., Postlethwait, John H., von Hippel, Frank A., Buck, C. Loren, and Cresko, William A.
Abstract:: Perchlorate is a common aquatic contaminant that has long been known to affect thyroid function in vertebrates, including humans. More recently perchlorate has been shown to affect primordial sexual differentiation in the aquatic model fishes zebrafish and threespine stickleback, but the mechanism has been unclear. Stickleback exposed to perchlorate from...
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Trait-mediated indirect interactions among residents of rocky shore tidepools

Creator:: Morgan, Steven G., Gravem, Sarah A., Lipus, Adam C., Grabiel, Marcos, and Miner, Benjamin G.
Abstract:: Trait-mediated indirect interactions (TMIIs) are an important component of food web structure and dynamics. We determined whether TMIIs occur in rocky tidepool communities on the west coast of the USA. In the laboratory, both adults and juveniles of the keystone predator Pisaster ochraceus and adults of a smaller predatory seastar...
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Three-Dimensional Reflectance Traction Microscopy

Creator:: Kim, Jihan, Jones, Christopher A. R., Groves, Nicholas Scott, and Sun, Bo
Abstract:: Cells in three-dimensional (3D) environments exhibit very different biochemical and biophysical phenotypes compared to the behavior of cells in two-dimensional (2D) environments. As an important biomechanical measurement, 2D traction force microscopy can not be directly extended into 3D cases. In order to quantitatively characterize the contraction field, we have developed...
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Sea Star Wasting Disease in the Keystone Predator Pisaster ochraceus in Oregon: Insights into Differential Population Impacts, Recovery, Predation Rate, and Temperature Effects from Long-Term Research

Creator:: Menge, Bruce A., Cerny-Chipman, Elizabeth B., Johnson, Angela, Sullivan, Jenna, Gravem, Sarah, and Chan, Francis
Abstract:: Sea star wasting disease (SSWD) first appeared in Oregon in April 2014, and by June had spread to most of the coast. Although delayed compared to areas to the north and south, SSWD was initially most intense in north and central Oregon and spread southward. Up to 90% of individuals...
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Identifying Malaria Transmission Foci for Elimination Using Human Mobility Data

Creator:: Ruktanonchai, Nick W., DeLeenheer, Patrick, Tatem, Andrew J., Alegana, Victor A., Caughlin, T. Trevor, zu Erbach-Schoenberg, Elisabeth, Lourenço, Christopher, Ruktanonchai, Corrine W., and Smith, David L.
Abstract:: Humans move frequently and tend to carry parasites among areas with endemic malaria and into areas where local transmission is unsustainable. Human-mediated parasite mobility can thus sustain parasite populations in areas where they would otherwise be absent. Data describing human mobility and malaria epidemiology can help classify landscapes into parasite...
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Full Text:: Human Mobility Data RESEARCH ARTICLE Identifying Malaria Transmission Foci for Elimination Using

Subsidies promote use of drought tolerant maize varieties despite variable yield performance under smallholder environments in Malawi

Creator:: Holden, Stein T. and Fisher, Monica
Abstract:: This study used a three-year panel dataset for 350 Malawian farm households to examine the potential for widespread adoption of drought tolerant (DT) maize varieties, a technology that holds considerable promise for helping smallholder farmers in Sub-Saharan Africa (SSA) adapt to drought risk. Regression results revealed that DT maize cultivation...
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Full Text:: favor of this explanation, but fur- ther research is needed to reach a conclusion. Key words

Persistent Chaos of Measles Epidemics in the Prevaccination United States Caused by a Small Change in Seasonal Transmission Patterns

Creator:: Dalziel, Benjamin D., Bjørnstad, Ottar N., van Panhuis, Willem G., Burke, Donald S., Metcalf, C. Jessica E., and Grenfell, Bryan T.
Abstract:: Epidemics of infectious diseases often occur in predictable limit cycles. Theory suggests these cycles can be disrupted by high amplitude seasonal fluctuations in transmission rates, resulting in deterministic chaos. However, persistent deterministic chaos has never been observed, in part because sufficiently large oscillations in transmission rates are uncommon. Where they...
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Community Water Improvement, Household Water Insecurity, and Women's Psychological Distress: An Intervention and Control Study in Ethiopia

Creator:: Stevenson, E. G. J., Ambelu, A., Caruso, B. A., Tesfaye, Y., and Freeman, M. C.
Abstract:: Background: Over 650 million people worldwide lack access to safe water supplies, and even among those who have gained access to ‘improved’ sources, water may be seasonally unreliable, far from homes, expensive, and provide insufficient quantity. Measurement of water access at the level of communities and households remains crude, and...
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Determinants of Human African Trypanosomiasis Elimination via Paratransgenesis

Creator:: Gilbert, Jennifer A., Medlock, Jan, Townsend, Jeffrey P., Aksoy, Serap, Mbah, Martial Ndeffo, and Galvani, Alison P.
Abstract:: Human African trypanosomiasis (HAT), transmitted by tsetse flies, has historically infected hundreds of thousands of individuals annually in sub-Saharan Africa. Over the last decade, concerted control efforts have reduced reported cases to below 10,000 annually, bringing complete elimination within reach. A potential technology to eliminate HAT involves rendering the flies...
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Abscisic acid transcriptomic signaling varies with grapevine organ

Creator:: Rattanakon, Supakan, Ghan, Ryan, Gambetta, Gregory A., Deluc, Laurent G., Schlauch, Karen A., and Cramer, Grant R.
Abstract:: Background: Abscisic acid (ABA) regulates various developmental processes and stress responses over both short (i.e. hours or days) and longer (i.e. months or seasons) time frames. To elucidate the transcriptional regulation of early responses of grapevine (Vitis vinifera) responding to ABA, different organs of grape (berries, shoot tips, leaves, roots...
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Full Text:: transcriptomic signaling varies with grapevine organ RESEARCH ARTICLE Open Access Abscisic acid transcriptomic

Seasonal cues induce phenotypic plasticity of Drosophila suzukii to enhance winter survival

Creator:: Shearer, Peter W., West, Jessica D., Walton, Vaughn M., Brown, Preston H., Svetec, Nicolas, and Chiu, Joanna C.
Abstract:: Background: As global climate change and exponential human population growth intensifies pressure on agricultural systems, the need to effectively manage invasive insect pests is becoming increasingly important to global food security. Drosophila suzukii is an invasive pest that drastically expanded its global range in a very short time since 2008,...
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Full Text:: (2016) 16:11 DOI 10.1186/s12898-016-0070-3 RESEARCH ARTICLE Seasonal cues induce phenotypic

Automated and Accurate Estimation of Gene Family Abundance from Shotgun Metagenomes

Creator:: Nayfach, Stephen, Bradley, Patrick H., Wyman, Stacia K., Laurent, Timothy J., Williams, Alex, Eisen, Jonathan A., Pollard, Katherine S., and Sharpton, Thomas J.
Abstract:: Shotgun metagenomic DNA sequencing is a widely applicable tool for characterizing the functions that are encoded by microbial communities. Several bioinformatic tools can be used to functionally annotate metagenomes, allowing researchers to draw inferences about the functional potential of the community and to identify putative functional biomarkers. However, little is...
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Full Text:: /journal.pcbi.1004573 Public Library of Science Version of Record http://cdss.library.oregonstate.edu/sa

Brain Meta-Transcriptomics from Harbor Seals to Infer the Role of the Microbiome and Virome in a Stranding Event

Creator:: Rosales, Stephanie M. and Thurber, Rebecca Vega
Abstract:: 29 Dec 2015: Rosales SM, Vega Thurber R (2015) Correction: Brain Meta-Transcriptomics from Harbor Seals to Infer the Role of the Microbiome and Virome in a Stranding Event. PLOS ONE 10(12): e0146208. https://doi.org/10.1371/journal.pone.0146208
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Estimating the Counterfactual Impact of Conservation Programs on Land Cover Outcomes: The Role of Matching and Panel Regression Techniques

Creator:: Jones, Kelly W. and Lewis, David J.
Abstract:: Deforestation and conversion of native habitats continues to be the leading driver of biodiversity and ecosystem service loss. A number of conservation policies and programs are implemented—from protected areas to payments for ecosystem services (PES)—to deter these losses. Currently, empirical evidence on whether these approaches stop or slow land cover...
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Full Text:: ), e0141380. doi:10.1371/journal.pone.0141380 10.1371/journal.pone.0141380 Public Library of Science

Theoretical Prediction of Disrupted Min Oscillation in Flattened Escherichia coli

Creator:: Schulte, Jeff B., Zeto, Rene W., and Roundy, David
Abstract:: The dynamics of the Min-protein system help Escherichia coli regulate the process of cell division by identifying the center of the cell. While this system exhibits robust bipolar oscillations in wild-type cell shapes, recent experiments have shown that when the cells are mechanically deformed into wide, flattened out, irregular shapes,...
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Full Text:: 10.1371/journal.pone.0139813 Public Library of Science Version of Record http

Genome-Wide Scan and Test of Candidate Genes in the Snail Biomphalaria glabrata Reveal New Locus Influencing Resistance to Schistosoma mansoni

Creator:: Tennessen, Jacob A., Bonner, Kaitlin M., Bollmann, Stephanie R., Johnstun, Joel A., Yeh, Jan-Ying, Marine, Melanie, Tavalire, Hannah F., Bayne, Christopher J., and Blouin, Michael S.
Abstract:: Background: New strategies to combat the global scourge of schistosomiasis may be revealed by increased understanding of the mechanisms by which the obligate snail host can resist the schistosome parasite. However, few molecular markers linked to resistance have been identified and characterized in snails. Methodology/Principal Findings: Here we test six...
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Full Text:: 10.1371/journal.pntd.0004077 Public Library of Science Version of Record http

Differential Expression of Ecdysone Receptor Leads to Variation in Phenotypic Plasticity across Serial Homologs

Creator:: Monteiro, Antónia, Tong, Xiaoling, Bear, Ashley, and Prudic, Kathleen L.
Abstract:: Bodies are often made of repeated units, or serial homologs, that develop using the same core gene regulatory network. Local inputs and modifications to this network allow serial homologs to evolve different morphologies, but currently we do not understand which modifications allow these repeated traits to evolve different levels of...
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Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish

Creator:: Evason, Kimberley J., Francisco, Macrina T., Juric, Vladislava, Balakrishnan, Sanjeev, del Pilar Lopez Pazmino, Maria, Gordan, John D., Kakar, Sanjay, Spitsbergen, Jan, Goga, Andrei, and Stainier, Didier Y. R.
Abstract:: Hepatocellular carcinoma (HCC) is one of the most lethal human cancers. The search for targeted treatments has been hampered by the lack of relevant animal models for the genetically diverse subsets of HCC, including the 20-40% of HCCs that are defined by activating mutations in the gene encoding β-catenin. To...
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Full Text:: 10.1371/journal.pgen.1005305 Public Library of Science Version of Record http

Grassland Arthropods Are Controlled by Direct and Indirect Interactions with Cattle but Are Largely Unaffected by Plant Provenance

Creator:: Farrell, Kelly Anne, Harpole, W. Stanley, Stein, Claudia, Suding, Katharine N., and Borer, Elizabeth T.
Abstract:: Cattle grazing and invasion by non-native plant species are globally-ubiquitous changes occurring to plant communities that are likely to reverberate through whole food webs. We used a manipulative field experiment to quantify how arthropod community structure differed in native and non-native California grassland communities in the presence and absence of...
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Full Text:: Library of Science Version of Record http://cdss.library.oregonstate.edu/sa-termsofuse RESEARCH

Hyperdiverse Gene Cluster in Snail Host Conveys Resistance to Human Schistosome Parasites

Creator:: Tennessen, Jacob A., Théron, André, Marine, Melanie, Yeh, Jan-Ying, Rognon, Anne, and Blouin, Michael S.
Abstract:: Schistosomiasis, a neglected global pandemic, may be curtailed by blocking transmission of the parasite via its intermediate hosts, aquatic snails. Elucidating the genetic basis of snail-schistosome interaction is a key to this strategy. Here we map a natural parasite-resistance polymorphism from a Caribbean population of the snail Biomphalaria glabrata. In...
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Full Text:: Public Library of Science Version of Record http://cdss.library.oregonstate.edu/sa-termsofuse

Delivery of Aerosolized Liposomal Amikacin as a Novel Approach for the Treatment of Nontuberculous Mycobacteria in an Experimental Model of Pulmonary Infection

Creator:: Rose, Sasha J., Neville, Mary E., Gupta, Renu, and Bermudez, Luiz E.
Abstract:: Pulmonary infections caused by nontuberculous mycobacteria (NTM) are an increasing problem in individuals with chronic lung conditions and current therapies are lacking. We investigated the activity of liposomal amikacin for inhalation (LAI) against NTM in vitro as well as in a murine model of respiratory infection. Macrophage monolayers were infected...
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Full Text:: /journal.pone.0108703 10.1371/journal.pone.0108703 Public Library of Science Version of Record http

Histopathologic Alterations Associated with Global Gene Expression Due to Chronic Dietary TCDD Exposure in Juvenile Zebrafish

Creator:: Liu, Qing, Spitsbergen, Jan M., Cariou, Ronan, Huang, Chun-Yuan, Jiang, Nan, Goetz, Giles, Hutz, Reinhold J., Tonellato, Peter J., and Carvan, Michael J., III
Abstract:: Correction 25 Aug 2014: The PLOS ONE Staff (2014) Correction: Histopathologic Alterations Associated with Global Gene Expression Due to Chronic Dietary TCDD Exposure in Juvenile Zebrafish. PLOS ONE 9(8): e106605. https://doi.org/10.1371/journal.pone.0106605
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WGSQuikr: Fast Whole-Genome Shotgun Metagenomic Classification

Creator:: Koslicki, David, Foucart, Simon, and Rosen, Gail
Abstract:: With the decrease in cost and increase in output of whole-genome shotgun technologies, many metagenomic studies are utilizing this approach in lieu of the more traditional 16S rRNA amplicon technique. Due to the large number of relatively short reads output from whole-genome shotgun technologies, there is a need for fast...
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Verification of Intraovum Transmission of a Microsporidium of Vertebrates: Pseudoloma neurophilia Infecting the Zebrafish, Danio rerio

Creator:: Sanders, Justin L., Watral, Virginia, Clarkson, Keri, and Kent, Michael L.
Abstract:: Direct transmission from parents to offspring, referred to as vertical transmission, occurs within essentially all major groups of pathogens. Several microsporidia (Phylum Microsporidia) that infect arthropods employ this mode of transmission, and various lines of evidence have suggested this might occur with certain fish microsporidia. The microsporidium, Pseudoloma neurophilia, is...
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Full Text:: laboratory model for toxicology, developmental biology, cancer, and infectious disease research. It has a

Successful Recovery of Nuclear Protein-Coding Genes from Small Insects in Museums Using Illumina Sequencing

Creator:: Kanda, Kojun, Pflug, James M., Sproul, John S., Dasenko, Mark A., and Maddison, David R.
Abstract:: Correction: 7 Mar 2016: The PLOS ONE Staff (2016) Correction: Successful Recovery of Nuclear Protein-Coding Genes from Small Insects in Museums Using Illumina Sequencing. PLOS ONE 11(3): e0151124. https://doi.org/10.1371/journal.pone.0151124
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Full Text:: /journal.pone.0143929 10.1371/journal.pone.0143929 Public Library of Science Version of Record http

Myosin-Powered Membrane Compartment Drives Cytoplasmic Streaming, Cell Expansion and Plant Development

Creator:: Peremyslov, Valera V., Cole, Rex A., Fowler, John E., and Dolja, Valerian V.
Abstract:: Using genetic approaches, particle image velocimetry and an inert tracer of cytoplasmic streaming, we have made a mechanistic connection between the motor proteins (myosins XI), cargo transported by these motors (distinct endomembrane compartment defined by membrane-anchored MyoB receptors) and the process of cytoplasmic streaming in plant cells. It is shown...
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Full Text:: /journal.pone.0139331 Public Library of Science Version of Record http://cdss.library.oregonstate.edu/sa

American pika in a low-elevation lava landscape: expanding the known distribution of a temperature-sensitive species

Creator:: Shinderman, Matt
Abstract:: In 2010, the American pika (Ochotona princeps fenisex) was denied federal protection based on limited evidence of persistence in low-elevation environments. Studies in nonalpine areas have been limited to relatively few environments, and it is unclear whether patterns observed elsewhere (e.g., Bodie, CA) represent other nonalpine habitats. This study was...
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Full Text:: -Cascades Circle of Excellence. Publication of this article in an open access journal was funded by the

Dynamics of Vector-Host Interactions in Avian Communities in Four Eastern Equine Encephalitis Virus Foci in the Northeastern US

Creator:: Molaei, Goudarz, Thomas, Michael C., Muller, Tim, Medlock, Jan, Shepard, John J., Armstrong, Philip M., and Andreadis, Theodore G.
Abstract:: Background: Eastern equine encephalitis (EEE) virus (Togaviridae, Alphavirus) is a highly pathogenic mosquito-borne zoonosis that is responsible for occasional outbreaks of severe disease in humans and equines, resulting in high mortality and neurological impairment in most survivors. In the past, human disease outbreaks in the northeastern U.S. have occurred intermittently...
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A Cost-Effectiveness Tool for Informing Policies on Zika Virus Control

Creator:: Alfaro-Murillo, Jorge A., Parpia, Alyssa S., Fitzpatrick, Meagan C., Tamagnan, Jules A., Medlock, Jan, Ndeffo-Mbah, Martial L., Fish, Durland, Ávila-Agüero, María L., Marín, Rodrigo, Ko, Albert I., Galvani, Alison P., and Carabin, Hélène
Abstract:: Background: As Zika virus continues to spread, decisions regarding resource allocations to control the outbreak underscore the need for a tool to weigh policies according to their cost and the health burden they could avert. For example, to combat the current Zika outbreak the US President requested the allocation of...
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Positive Impact of Nutritional Interventions on Serum Symmetric Dimethylarginine and Creatinine Concentrations in Client-Owned Geriatric Dogs

Creator:: Hall, Jean A., MacLeay, Jennifer, Yerramilli, Maha, Obare, Edward, Yerramilli, Murthy, Schiefelbein, Heidi, Paetau-Robinson, Inke, and Jewell, Dennis E.
Abstract:: A prospective study was conducted in client-owned geriatric dogs to evaluate the short-term effects of a test food on serum symmetric dimethylarginine (SDMA) and creatinine (Cr) concentrations. Test food contained functional lipids (fish oil), antioxidants (lipoic acid, vitamins C and E), L-carnitine, botanicals (fruits and vegetables), controlled sodium concentration, and...
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Full Text:: Dimethylarginine and Creatinine Concentrations in Client-Owned Geriatric Dogs RESEARCH ARTICLE Positive Impact

Biological screening of selected Pacific Northwest forest plants using the brine shrimp (Artemia salina) toxicity bioassay

Creator:: Karchesy, Yvette M., Kelsey, Rick G., Constantine, George, and Karchesy, Joseph J.
Abstract:: The brine shrimp (Artemia salina) bioassay was used to screen 211 methanol extracts from 128 species of Pacific Northwest plants in search of general cytotoxic activity. Strong toxicity (LC₅₀ < 100 µg/ml) was found for 17 extracts from 13 species, with highest activity observed for Angelica arguta roots at <10...
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Full Text:: Karchesy et al. SpringerPlus (2016) 5:510 DOI 10.1186/s40064-016-2145-1 RESEARCH Biological screening

Positive Impact of Nutritional Interventions on Serum Symmetric Dimethylarginine and Creatinine Concentrations in Client-Owned Geriatric Cats

Creator:: Hall, Jean A., MacLeay, Jennifer, Yerramilli, Maha, Obare, Edward, Yerramilli, Murthy, Schiefelbein, Heidi, Paetau-Robinson, Inke, and Jewell, Dennis E.
Abstract:: A prospective study was conducted in client-owned geriatric cats to evaluate the short- term effects of a test food on serum symmetric dimethylarginine (SDMA) and creatinine (Cr) concentrations. Test food contained functional lipids (fish oil), antioxidants (vitamins C and E), L-carnitine, botanicals (vegetables), highly bioavailable protein, and amino acid supplements....
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Full Text:: Dimethylarginine and Creatinine Concentrations in Client-Owned Geriatric Cats RESEARCH ARTICLE Positive Impact

Evaluating Temporal Consistency in Marine Biodiversity Hotspots

Creator:: Piacenza, Susan E., Thurman, Lindsey L., Barner, Allison K., Benkwitt, Cassandra E., Boersma, Kate S., Cerny-Chipman, Elizabeth B., Ingeman, Kurt E., Kindinger, Tye L., Lindsley, Amy J., Nelson, Jake, Reimer, Jessica N., Rowe, Jennifer C., Shen, Chenchen, Thompson, Kevin A., and Heppell, Selina S.
Abstract:: With the ongoing crisis of biodiversity loss and limited resources for conservation, the concept of biodiversity hotspots has been useful in determining conservation priority areas. However, there has been limited research into how temporal variability in biodiversity may influence conservation area prioritization. To address this information gap, we present an...
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Full Text:: Public Library of Science Version of Record http://cdss.library.oregonstate.edu/sa-termsofuse

Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon

Creator:: Rajendran, Praveen, Dashwood, Wan-Mohaiza, Li, Li, Kang, Yuki, Kim, Eunah, Johnson, Gavin, Fischer, Kay A., Löhr, Christiane V., Williams, David E., Ho, Emily, Yamamoto, Masayuki, Lieberman, David A., and Dashwood, Roderick H.
Abstract:: Background: The dietary agent sulforaphane (SFN) has been reported to induce nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2)-dependent pathways as well as inhibiting histone deacetylase (HDAC) activity. The current investigation sought to examine the relationships between Nrf2 status and HDAC expression in preclinical and translational studies. Results: Wild type...
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From the President : Shifting waters

Creator:: Abbott, Mark R.
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Full Text:: teaching and research. Republication, systematic reproduction, or collective redistribution of any

Hydroacoustic monitoring of oceanic spreading centers: Past, present, and future

Creator:: Dziak, Robert P., Bohnenstiehl, Delwayne R., and Smith, Deborah K.
Abstract:: Mid-ocean ridge volcanism and extensional faulting are the fundamental processes that lead to the creation and rifting of oceanic crust, yet these events go largely undetected in the deep ocean. Currently, the only means available to observe seafloor-spreading events in real time is via the remote detection of the seismicity...
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Full Text:: teaching and research. Republication, systematic reproduction, or collective redistribution of any

Are Any Coastal Internal Tides Predictable?

Creator:: Nash, Jonathan D., Shroyer, Emily L., Kelly, Samuel M., Inall, Mark E., Duda, Timothy F., Levine, Murray D., Jones, Nicole L., and Musgrave, Ruth C.
Abstract:: Surface tides are the heartbeat of the ocean. Because they are controlled by Earth's motion relative to other astronomical objects in our solar system, surface tides act like clockwork and generate highly deterministic ebb and flow familiar to all mariners. In contrast, baroclinic motions at tidal frequencies are much more...
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Full Text:: . Samuel M. Kelly is Research Fellow, University of Western Australia, Perth, Australia. Mark E. Inall is

Volcanic Eruptions in the Deep Sea

Creator:: Rubin, Kenneth H., Soule, S. Adam, Chadwick, William W., Jr., Fornari, Daniel J., Clague, David A., Embley, Robert W., Baker, Edward T., Perfit, Michael R., Caress, David W., and Dziak, Robert P.
Abstract:: Volcanic eruptions are important events in Earth’s cycle of magma generation and crustal construction. Over durations of hours to years, eruptions produce new deposits of lava and/or fragmentary ejecta, transfer heat and magmatic volatiles from Earth’s interior to the overlying air or seawater, and significantly modify the landscape and perturb...
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Full Text:: Permission is granted to copy this article for use in teaching and research. Republication, systematic

Eddy dynamics from satellite altimetry

Creator:: Fu, Lee-Lueng, Chelton, Dudley B., Le Traon, Pierre-Yves, and Morrow, Rosemary
Abstract:: Most of the kinetic energy of ocean circulation is contained in ubiquitous mesoscale eddies. Their prominent signatures in sea surface height have rendered satellite altimetry highly effective in observing global ocean eddies. Our knowledge of ocean eddy dynamics has grown by leaps and bounds since the advent of satellite altimetry...
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Full Text:: article for use in teaching and research. Republication, systematic reproduction, or collective

Coupled ocean-atmosphere interaction at oceanic mesoscales

Creator:: Chelton, Dudley B. and Xie, Shang-Ping
Abstract:: Satellite observations have revealed a remarkably strong positive correlation between sea surface temperature (SST) and surface winds on oceanic mesoscales of 10–1000 km. Although SST influence on the atmosphere had previously been identified from several in situ observational studies, its widespread existence in regions of strong SST gradients throughout the...
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Full Text:: teaching and research. Republication, systematic reproduction, or collective redistribution of any

Burning the legacy? Influence of wildfire reburn on dead wood dynamics in a temperate conifer forest

Creator:: Donato, Daniel C., Fontaine, Joseph B., and Campbell, John L.
Abstract:: Dynamics of dead wood, a key component of forest structure, are not well described for mixed-severity fire regimes with widely varying fire intervals. A prominent form of such variation is when two stand-replacing fires occur in rapid succession, commonly termed an early-seral “reburn.” These events are thought to strongly influence...
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Full Text:: . ACKNOWLEDGMENTS This research was supported by the Joint Fire Science Program and facilitated by the Rogue

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