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Filtering by: Creator Zhang, Zhi Non-Academic Affiliation Oregon State University. Bioresource Research

Genotyping Cytochrome P450 1B1*3(Phase I) and Glutathione S-transferase Mu 1 null (Phase II), Metabolizing Enzymes in a [14C]Benzo[a]pyrene Human Micro Dosing Study

Creator:

Luo, Yun L.

Abstract:

Polycyclic Aromatic Hydrocarbons (PAHs) have been studied for their carcinogenic toxicity. PAHs are formed by incomplete carbon combustion. Benzo[a]pyrene (BaP) is an IARC classified Class 1 Human carcinogenic PAH. New studies are conducted to gain a better understanding of PAHs and how to reduce exposure. Glutathione S-transferase M 1 (GSTM1...

Resource Type:

Honors College Thesis

Full Text:

(Zhang et al., 2013 & Yu et al., 2016). GSTM1 assists in detoxication of foreign xenobiotics via
Targeting chemotherapeutic resistance in breast cancer

Creator:

Avery, Jonathan

Abstract:

The Bcl-2 family of proteins regulate cell survival and are targets for cancer therapy. This protein family has also been implicated in chemotherapeutic resistance, the cause of approximately 90% of treatment failure in advanced cancer. We analyzed the expression and the role of the Bcl-2 proteins in chemotherapy resistant breast...

Resource Type:

Undergraduate Thesis

Full Text:

Liu, Young-Hoon Han, Xihua Cao, Marcia I Dawson, John C Reed, and Xiao-kun Zhang. 2004. “Conversion