Chemical compounds produced by organisms, or natural products, are excellent sources of inspiration for anticancer pharmaceutical discovery (Rodrigues et al., 2016). Microtubule targeting agents are a specific class of compounds, often discovered from natural sources, that have been developed as clinically successful anticancer therapies (Steinmetz and Prota, 2018). In the...
Pacific lamprey Entosphenus tridentatus is a valuable icon and traditional food source for Indigenous people of western North America. Native Americans have utilized traditional ecological knowledge (TEK) since time immemorial to guide their ways of life, transmitting cultural values and natural history to further generational knowledge. Pacific lamprey are in...
Small groups are an important and widely used educational
format in adult church education. It is estimated
that ninety percent of the churches that belong to the
Conservative Baptist Association of Oregon provide some
type of small group eductional opportunity for their adult
members. The purpose of this study was...
I defend robust realism from arguments that raise epistemological challenges to it based on considerations about either moral disagreement or the genealogy of our moral beliefs. The first argument is the “Argument from Conciliationism,” which contends that the moral disagreements that obtain between moral peers give us reason to believe...
This study examined the existence and effectiveness of current
pesticide management programs in the Caribbean region. A questionnaire
was developed to assess the current pesticide managment programs in
the Caribbean region and to determine the strengths and weaknesses of
the existing education and training programs, governmental policies,
and other resources....
The amount of energy we use and the ways that we get that energy sit on the edge of dramatic change as the carbon budget which can keep the planet under 1.5C of global average temperature increase gets smaller (Allen, 2018). In response, we continue to research and develop renewable...
This report is intended to increase the understanding of interrelationships in a small farming community. It consists of three main sections. First, it begins with an historical review of agriculture in the Willamette Valley, Oregon. Since every agricultural region has unique components it is important to begin any modeling process...
All mammals host communities of commensal microbes in and on their bodies. Recent technological advances, combined with experimental studies in laboratory animals, are beginning to reveal the ubiquitous links between the gut microbiome and host disease, metabolism, immunity, and numerous other host functions. A new challenge of microbiome research is...
Dearomatization reactions exist broadly in biosynthesis and chemical synthesis. The highly functionalized atoms of arenes can be masked by it aromaticity, and upon dearomatization, those reactive atoms can be readily applied to bond formation and further manipulation. The total synthesis of (–)-cephalotaxine and (–)- homoharringtonine is described via an oxidative...