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Good, Laura H.
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- Creator:
- Watson, Gregory, Beaver, Laura M., Williams, David, Dashwood, Roderick H., and Ho, Emily
- Abstract:
- Epidemiological evidence has demonstrated a reduced risk of prostate cancer associated with cruciferous vegetable intake. Follow-up studies have attributed this protective activity to the metabolic products of glucosinolates, a class of secondary metabolites produced by crucifers. The metabolic products of glucoraphanin and glucobrassicin, sulforaphane and indole-3-carbinol respectively, have been the...
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- Article
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- Creator:
- Burnett, Margaret M., Beckwith, Laura, Wiedenbeck, Susan, Fleming, Scott D., Cao, Jill, Park, Thomas H., Grigoreanu, Valentina, and Rector, Kyle
- Abstract:
- Although there has been significant research into gender regarding educational and workplace practices, there has been little awareness of gender differences as they pertain to software tools, such as spreadsheet applications, that try to support end users in problem-solving tasks. Although such software tools are intended to be gender agnostic,...
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- Article
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- Problem-‐Solving Software Margaret M. Burnetta, Laura Beckwitha,c, Susan Wiedenbeckb, Scott D
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- Creator:
- Wong, Carmen P., Hsu, Anna, Buchanan, Alex, Palomera-Sanchez, Zoraya, Beaver, Laura M., Houseman, E. Andres, Williams, David E., Dashwood, Roderick H., and Ho, Emily
- Abstract:
- Epigenetic changes, including aberrant DNA methylation, result in altered gene expression and play an important role in carcinogenesis. Phytochemicals such as sulforaphane (SFN) and 3,3′-diindolylmethane (DIM) are promising chemopreventive agents for the treatment of prostate cancer. Both have been shown to induce re-expression of genes, including tumor suppressor genes silenced...
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- Article
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- Creator:
- Bonito, Gregory, Smith, Matthew E., Nowak, Michael, Healy, Rosanne A., Guevara, Gonzalo, Cazares, Efren, Kinoshita, Akihiko, Nouhra, Eduardo R., Domınguez, Laura S., Tedersoo, Leho, Murat, Claude, Wang, Yun, Arroyo Moreno, Baldomero, Pfister, Donald H., Nara, Kazuhide, Zambonelli, Alessandra, Trappe, James M., and Vilgalys, Rytas
- Abstract:
- Truffles have evolved from epigeous (aboveground) ancestors in nearly every major lineage of fleshy fungi. Because accelerated rates of morphological evolution accompany the transition to the truffle form, closely related epigeous ancestors remain unknown for most truffle lineages. This is the case for the quintessential truffle genus Tuber, which includes...
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- Article
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- , Akihiko Kinoshita11, Eduardo R. Nouhra5, Laura S. Domı́nguez5, Leho Tedersoo6, Claude Murat7, Yun Wang8
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- Creator:
- Robey, R. Brooks, Weisz, Judith, Kuemmerle, Nancy B., Salzberg, Anna C., Berg, Arthur, Brown, Dustin G., Kubik, Laura, Palorini, Roberta, Al-Mulla, Fahd, Al-Temaimi, Rabeah, Colacci, Anna Maria, Mondello, Chiara, Raju, Jayadev, Woodrick, Jordan, Scovassi, A. Ivana, Singh, Neetu, Vaccari, Monica, Roy, Rabindra, Forte, Stefano, Memeo, Lorenzo, Salem, Hosni K., Amedei, Amedeo, Hamid, Roslida A., Williams, Graeme P., Lowe, Leroy, Meyer, Joel, Martin, Francis L., Bisson, William H., Chiaradonna, Ferdinando, and Ryan, Elizabeth P.
- Abstract:
- Environmental contributions to cancer development are widely accepted, but only a fraction of all pertinent exposures have probably been identified. Traditional toxicological approaches to the problem have largely focused on the effects of individual agents at singular endpoints. As such, they have incompletely addressed both the pro-carcinogenic contributions of environmentally...
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- Article
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- Creator:
- Casey, Stephanie C., Vaccari, Monica, Al-Mulla, Fahd, Al-Temaimi, Rabeah, Amedei, Amedeo, Barcellos-Hoff, Mary Helen, Brown, Dustin G., Chapellier, Marion, Christopher, Joseph, Curran, Colleen S., Forte, Stefano, Hamid, Roslida A., Heneberg, Petr, Koch, Daniel C., Krishnakumar, P. K., Laconi, Ezio, Maguer-Satta, Veronique, Marongiu, Fabio, Memeo, Lorenzo, Mondello, Chiara, Raju, Jayadev, Roman, Jesse, Roy, Rabindra, Ryan, Elizabeth P., Ryeom, Sandra, Salem, Hosni K., Scovassi, A. Ivana, Singh, Neetu, Soucek, Laura, Vermeulen, Louis, Whitfield, Jonathan R., Woodrick, Jordan, Colacci, Annamaria, Bisson, William H., and Felsher, Dean W.
- Abstract:
- Potentially carcinogenic compounds may cause cancer through direct DNA damage or through indirect cellular or physiological effects. To study possible carcinogens, the fields of endocrinology, genetics, epigenetics, medicine, environmental health, toxicology, pharmacology and oncology must be considered. Disruptive chemicals may also contribute to multiple stages of tumor development through effects...
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- Article
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- ., Barcellos-Hoff, M. H., ... & Felsher, D. W. (2015). The effect of environmental chemicals on the tumor
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- Creator:
- Seabloom, Eric W., Borer, Elizabeth T., Buckley, Yvonne M., Cleland, Elsa E., Davies, Kendi F., Firn, Jennifer, Harpole, W. Stanley, Hautier, Yann, Lind, Eric M., MacDougall, Andrew S., Orrock, John L., Prober, Suzanne M., Adler, Peter B., Anderson, T. Michael, Bakker, Jonathan D., Biederman, Lori A., Blumenthal, Dana M., Brown, Cynthia S., Brudvig, Lars A., Cadotte, Marc, Chu, Chengjin, Cottingham, Kathryn L., Crawley, Michael J., Damschen, Ellen I., Dantonio, Carla M., DeCrappeo, Nicole M., Du, Guozhen, Fay, Philip A., Frater, Paul, Gruner, Daniel S., Hagenah, Nicole, Hector, Andy, Hillebrand, Helmut, Hofmockel, Kirsten S., Humphries, Hope C., Jin, Virginia L., Kay, Adam, Kirkman, Kevin P., Klein, Julia A., Knops, Johannes M. H., La Pierre, Kimberly J., Ladwig, Laura, Lambrinos, John G., Li, Qi, Li, Wei, Marushia, Robin, McCulley, Rebecca L., Melbourne, Brett A., Mitchell, Charles E., Moore, Joslin L., Morgan, John, Mortensen, Brent, O'Halloran, Lydia R., Pyke, David A., Risch, Anita C., Sankaran, Mahesh, Schuetz, Martin, Simonsen, Anna, Smith, Melinda D., Stevens, Carly J., Sullivan, Lauren, Wolkovich, Elizabeth, Wragg, Peter D., Wright, Justin, and Yang, Louie
- Abstract:
- Exotic species dominate many communities; however the functional significance of species’ biogeographic origin remains highly contentious. This debate is fuelled in part by the lack of globally replicated, systematic data assessing the relationship between species provenance, function and response to perturbations. We examined the abundance of native and exotic plant...
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- Article
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Predicting invasion in grassland ecosystems: is exotic dominance the real embarrassment of richness?
- Creator:
- Seabloom, Eric W., Borer, Elizabeth T., Buckley, Yvonne, Cleland, Elsa E., Davies, Kendi, Firn, Jennifer, Harpole, W. Stanley, Hautier, Yann, Lind, Eric, Macdougall, Andrew, Orrock, John L., Prober, Suzanne M., Adler, Peter, Alberti, Juan, Anderson, T. Michael, Bakker, Jonathan D., Biederman, Lori A., Blumenthal, Dana, Brown, Cynthia S., Brudvig, Lars A., Caldeira, Maria, Chu, Chengjin, Crawley, Michael J., Daleo, Pedro, Damschen, Ellen I., D'Antonio, Carla M., Decrappeo, Nicole M., Dickman, Chris R., Du, Guozhen, Fay, Philip A., Frater, Paul, Gruner, Daniel S., Hagenah, Nicole, Hector, Andrew, Helm, Aveliina, Hillebrand, Helmut, Hofmockel, Kirsten S., Humphries, Hope C., Iribarne, Oscar, Jin, Virginia L., Kay, Adam, Kirkman, Kevin P., Klein, Julia A., Knops, Johannes M. H., La Pierre, Kimberly J., Ladwig, Laura M., Lambrinos, John G., Leakey, Andrew D. B., Li, Qi, Li, Wei, Mcculley, Rebecca, Melbourne, Brett, Mitchell, Charles E., Moore, Joslin L., Morgan, John, Mortensen, Brent, O'Halloran, Lydia R., Paertel, Meelis, Pascual, Jesus, Pyke, David A., Risch, Anita C., Salguero-Gomez, Roberto, Sankaran, Mahesh, Schuetz, Martin, Simonsen, Anna, Smith, Melinda, Stevens, Carly, Sullivan, Lauren, Wardle, Glenda M., Wolkovich, Elizabeth M., Wragg, Peter D., Wright, Justin, and Yang, Louie
- Abstract:
- Invasions have increased the size of regional species pools, but are typically assumed to reduce native diversity. However, global-scale tests of this assumption have been elusive because of the focus on exotic species richness, rather than relative abundance. This is problematic because low invader richness can indicate invasion resistance by...
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- Article
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- Creator:
- Goodson, William H., III, Lowe, Leroy, Carpenter, David O., Gilbertson, Michael, Manaf Ali, Abdul, Lopez de Cerain Salsamendi, Adela, Lasfar, Ahmed, Carnero, Amancio, Azqueta, Amaya, Amedei, Amedeo, Charles, Amelia K., Collins, Andrew R., Ward, Andrew, Salzberg, Anna C., Colacci, Annamaria, Olsen, Ann-Karin, Berg, Arthur, Barclay, Barry J., Zhou, Binhua P., Blanco-Aparicio, Carmen, Baglole, Carolyn J., Dong, Chenfang, Mondello, Chiara, Hsu, Chia-Wen, Naus, Christian C., Yedjou, Clement, Curran, Colleen S., Laird, Dale W., Koch, Daniel C., Carlin, Danielle J., Felsher, Dean W., Roy, Debasish, Brown, Dustin G., Ratovitski, Edward, Ryan, Elizabeth P., Corsini, Emanuela, Rojas, Emilio, Moon, Eun-Yi, Laconi, Ezio, Marongiu, Fabio, Al-Mulla, Fahd, Chiaradonna, Ferdinando, Darroudi, Firouz, Martin, Francis L., Van Schooten, Frederik J., Goldberg, Gary S., Wagemaker, Gerard, Nangami, Gladys N., Calaf, Gloria M., Williams, Graeme P., Wolf, Gregory T., Koppen, Gudrun, Brunborg, Gunnar, Lyerly, H. Kim, Krishnan, Harini, Ab Hamid, Hasiah, Yasaei, Hemad, Sone, Hideko, Kondoh, Hiroshi, Salem, Hosni K., Hsu, Hsue-Yin, Park, Hyun Ho, Koturbash, Igor, Miousse, Isabelle R., Scovassi, A.Ivana, Klaunig, James E., Vondráček, Jan, Raju, Jayadev, Roman, Jesse, Wise, John P., Sr., Whitfield, Jonathan R., Woodrick, Jordan, Christopher, Joseph A., Ochieng, Josiah, Martinez-Leal, Juan F., Weisz, Judith, Kravchenko, Julia, Sun, Jun, Prudhomme, Kalan R., Narayanan, Kannan B., Cohen-Solal, Karine A., Moorwood, Kim, Gonzalez, Laetitia, Soucek, Laura, Jian, Le, D’Abronzo, Leandro S., Lin, Liang-Tzung, Li, Lin, Gulliver, Linda, McCawley, Lisa J., Memeo, Lorenzo, Vermeulen, Louis, Leyns, Luc, Zhang, Luoping, Valverde, Mahara, Khatami, Mahin, Romano, Maria F., Chapellier, Marion, Williams, Marc A., Wade, Mark, Manjili, Masoud H., Lleonart, Matilde E., Xia, Menghang, Gonzalez Guzman, Michael J., Karamouzis, Michalis V., Kirsch-Volders, Micheline, Vaccari, Monica, Kuemmerle, Nancy B., Singh, Neetu, Cruickshanks, Nichola, Kleinstreuer, Nicole, van Larebeke, Nik, Ahmed, Nuzhat, Ogunkua, Olugbemiga, Krishnakumar, P. K., Vadgama, Pankaj, Marignani, Paola A., Ghosh, Paramita M., Ostrosky-Wegman, Patricia, Thompson, Patricia A., Dent, Paul, Heneberg, Petr, Darbre, Philippa, Leung, Po Sing, Nangia-Makker, Pratima, Cheng, Qiang, Robey, R. Brooks, Al-Temaimi, Rabeah, Roy, Rabindra, Andrade-Vieira, Rafaela, Sinha, Ranjeet K., Mehta, Rekha, Vento, Renza, Di Fiore, Riccardo, Ponce-Cusi, Richard, Dornetshuber-Fleiss, Rita, Nahta, Rita, Castellino, Robert C., Palorini, Roberta, Hamid, Roslida A., Langie, Sabine A. S., Eltom, Sakina E., Brooks, Samira A., Ryeom, Sandra, Wise, Sandra S., Bay, Sarah N., Harris, Shelley A., Papagerakis, Silvana, Romano, Simona, Pavanello, Sofia, Eriksson, Staffan, Forte, Stefano, Casey, Stephanie C., Luanpitpong, Sudjit, Lee, Tae-Jin, Otsuki, Takemi, Chen, Tao, Massfelder, Thierry, Sanderson, Thomas, Guarnieri, Tiziana, Hultman, Tove, Dormoy, Valérian, Odero-Marah, Valerie, Sabbisetti, Venkata, Maguer-Satta, Veronique, Rathmell, W. Kimryn, Engström, Wilhelm, Decker, William K., Bisson, William H., Rojanasakul, Yon, Luqmani, Yunus, Chen, Zhenbang, and Hu, Zhiwei
- Abstract:
- Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide, but credible estimates from the World Health Organization and the International Agency for Research on Cancer (IARC) suggest that the fraction of cancers attributable to toxic environmental exposures is between 7% and 19%. To explore the hypothesis that...
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- Article
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- environment: the challenge ahead Goodson, W. H., Lowe, L., Carpenter, D. O., Gilbertson, M., Ali, A. M., de