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Towards the Perfect Marriage Between Theory and Experiments in Drug Discovery and Synthesis : Insights into Structure Determination of Complex Natural Products and Mechanistic Understandings of Lactam Synthesis

Creator:: Snyder, Kevin M.
Abstract:: In this report, three studies are presented that aid in the development of drug discovery and their synthesis. In each, the importance of the marriage between computations and experiments is highlighted. Continued efforts in this vein are essential for future efforts towards improving human health. The first case study investigated...
Resource Type:: Masters Thesis
Full Text:: Coat; Henry Holt Publishers: New York, 2004. (C) Wainwright, M. Miracle Cure: The Story of Penicillin

The Production and Human Taste Detection of Glucose Polymers with Distinct Chain Length Ranges

Creator:: Balto, Amy
Abstract:: A majority of human caloric intake is in the form of complex carbohydrates, which have been assumed to be tasteless. However, there is considerable evidence from rat and human studies to support the existence of a secondary carbohydrate taste receptor that detects glucose polymers. Psychophysical studies in our lab suggest...
Resource Type:: Masters Thesis
Full Text:: ) first 90% ethanol extract of CSS; (b) sixth 90% ethanol extract of CSS; (c) second 70% ethanol extract

The preparation of common prebiotic oligosaccharides with defined degree of polymerization

Creator:: Ooi, Megan C. Y.
Abstract:: Prebiotics are a subset of dietary fiber that is growing in demand within the food industry. The health benefits of prebiotics have been well established, leading to the increase in its incorporation into various food products. Given the importance of prebiotics as functional ingredients, it is important to understand their...
Resource Type:: Masters Thesis
Full Text:: oligosaccharide with defined degree of polymerization Megan Ooi, XIaojie Zhang, Christopher M. Beaudry

The Preparation and Human Taste Detection of Maltooligosaccharides with Varying Degrees of Polymerization

Creator:: Andrewson, Toren S.
Abstract:: Starch is a significant component of the human diet and the glucose produced through its digestion provides a critical source of energy. When starch enters the mouth, salivary α-amylase hydrolyzes it into maltooligosaccharides (MOS, degree of polymerization [DP] 3-20) and maltopolysaccharides (MPS, DP >20). Previous studies have found that humans...
Resource Type:: Masters Thesis
Full Text:: from Michael H. Penner. Christopher M. Beaudry, Xiaojie Zhang, and Tucker Hamilton assisted with NMR

The preparation and human taste detection of low degree of polymerization glucose oligomers

Creator:: Pullicin, Alexa J.
Abstract:: There is growing evidence that humans and other animals can taste certain starch hydrolysis products, namely, maltooligosaccharides (MOS), and that their detection is independent of the known sweet receptor, T1R2 T1R3. The overall goal of this study was to further investigate the taste perception of low degree-of-polymerization (DP) MOS in...
Resource Type:: Masters Thesis
Full Text:: 3 was written by Alexa Pullicin and Michael Penner with inputs from Juyun Lim. Christopher Beaudry

The Impact of Parasitic Copepod Salmincola Californiensis on Swimming Ability & Oxidative Burst Activity in Response to Stress in Juvenile Chinook Salmon

Creator:: Herron-Seeley, Crystal L.
Abstract:: Juvenile Chinook Salmon (Oncorhynchus tshawytscha) have a finite amount of energy that they can use to move from their riverine habitat to their oceanic habitat. Fish in the Willamette River Basin are prevented from moving to the ocean easily by dams which create reservoirs, where they reside for up to...
Resource Type:: Masters Thesis
Full Text:: & Shellfish Immunology 31(3):381-388. Keefer, M. L., G. A. Taylor, D. F. Garletts, C. K. Hems, G. A

The archaeology of the Smith House (ORYA3), Dayton, Oregon

Creator:: Stone, Helen Delight
Abstract:: Site ORYA3, the Smith House, is located in Dayton, Oregon. The archaeological project originated because owners of this structure, listed on the National Register of Historic Places, applied for a demolition permit. The 1859 home, first occupied by two early Oregon pioneers, Andrew and Sarah Smith, was considered architecturally significant,...
Resource Type:: Masters Thesis
Full Text:: ... Town of DAYFON c. 1900 j m MAP OF DAYTON AS IT APPEARED ABOUT THE TURN OF THE CENTURY 1. Free

Synthetic studies toward the total synthesis of azaspiracid-1

Creator:: Su, Dong
Abstract:: Azaspiracid-1, a novel marine toxin that contains 9 rings and 20 stereogenic centers, has drawn considerable attention from synthetic groups worldwide due to its structural complexity, which includes a unique trioxabisspiroketal fused to a tetrahydrofuran ring (ABCD rings), a piperidine-tetrahydrofuran spiroaminal system fused to a 2,9-dioxabicyclo[3.3.1]nonane system (FGHI rings), a...
Resource Type:: Masters Thesis

Survival of Listeria monocytogenes, Salmonella spp., and Staphylococcus aureus in raw yellowfin tuna during refrigerated and frozen storage

Creator:: Mou, Jing
Abstract:: The consumption of seafood in the United States has increased rapidly in recent years due to high quality protein and health benefits of seafood. Seafood can be a carrier for bacteria normally distributed in the marine environment and, in some cases, can be contaminated by human pathogens. Therefore, there is...
Resource Type:: Masters Thesis
Full Text:: at 5 - 7 °C for 14 days revealed that L. monocytogenes had the ability to multiply in the tuna meat

Storage quality of broccoli florets and evaluation of modified atmosphere packaging

Creator:: Cabezas, Amalia
Abstract:: The effect of some factors that can affect quality characteristics of broccoli florets in storage was evaluated. Quality characteristics of broccoli florets with different rates of field nitrogen (N) application (0, 90, 180, and 270 Kg N/ha from urea) were evaluated in modified atmosphere packaging (MAP) (B-900 Cryovac film) storage...
Resource Type:: Masters Thesis
Full Text:: Acid (vitamin C) 72 Conclusions 77 Table of Contents (Continued) Page Chapter 4. Storage

ScholarsArchive@OSU

Towards the Perfect Marriage Between Theory and Experiments in Drug Discovery and Synthesis : Insights into Structure Determination of Complex Natural Products and Mechanistic Understandings of Lactam Synthesis

The Production and Human Taste Detection of Glucose Polymers with Distinct Chain Length Ranges

The preparation of common prebiotic oligosaccharides with defined degree of polymerization

The Preparation and Human Taste Detection of Maltooligosaccharides with Varying Degrees of Polymerization

The preparation and human taste detection of low degree of polymerization glucose oligomers

The Impact of Parasitic Copepod Salmincola Californiensis on Swimming Ability & Oxidative Burst Activity in Response to Stress in Juvenile Chinook Salmon

The archaeology of the Smith House (ORYA3), Dayton, Oregon

Synthetic studies toward the total synthesis of azaspiracid-1

Survival of Listeria monocytogenes, Salmonella spp., and Staphylococcus aureus in raw yellowfin tuna during refrigerated and frozen storage

Storage quality of broccoli florets and evaluation of modified atmosphere packaging

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