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  • The influence of selenium on selenoprotein W

    Creator:
    Yeh, Jan-ying
    Abstract:
    The objective of our study was to investigate the effect of selenium on selenoprotein W. Western blot analysis indicated that selenoprotein W is present in muscle, brain, testis and spleen of rat tissues. Tissue distribution of selenoprotein W was not altered in rats fed various selenium levels. Among muscle, brain,...
    Resource Type:
    Dissertation
    Full Text:
    were incubated with 10-7 M selenium, whereas selenoprotein W mRNA reached a plateau with 10' M

  • Biochemical and molecular characteristics of selenoprotein W

    Creator:
    Gu, Qiu-Ping
    Resource Type:
    Dissertation
    Full Text:
    , decoding of the selenoprotein mRNA pauses or terminates at the UGA codon (Leinfelder et al, 1988

  • Selenoprotein W : distribution and function in rat tissue and cultured cells

    Creator:
    Sun, Yu, 1963-
    Abstract:
    The objective of this study was to further determine the distribution of selenoprotein W (SeW) in tissues from rats and sheep fed different selenium levels and to search for the possible functions of this protein. In the rat study a total of 28 rat tissues were examined and SeW was...
    Resource Type:
    Dissertation
    Full Text:
    required for selenoprotein synthesis and selenocysteine incorporation (Leinfelder et al., 1988). The Se1A

  • Characterization of rodent selenoprotein W promoter

    Creator:
    Amantana, Adams
    Abstract:
    Rat selenoprotein W (SeW) promoter activity was investigated using different concentrations of cadmium, copper, and zinc. Two fragments (404bp and 1265bp) of the SeW promoter, containing a single metal response element (MRE), were ligated into the multiple cloning site of a pGL3-Basic reporter plasmid. The constructs were transfected into cultured...
    Resource Type:
    Dissertation
    Full Text:
    ................................................................... 26 2.(a) Activity of unmutated (N) and mutant (M) versions of 404bp promoter constructs in 6-day

  • Effect of vitamin B-6 status on Selenium metabolism in the rat

    Creator:
    Beilstein, Michael A.
    Resource Type:
    Masters Thesis
    Full Text:
    with a Potter-Elvehjem apparatus in ten volumes of ice-cold 0.1 M sodium phosphate buffer, pH 7.5