Index Catalog // ScholarsArchive@OSU

Naphthalocyanine-Based Biodegradable Polymeric Nanoparticles for Image-Guided Combinatorial Phototherapy

Creator:: Taratula, Olena, Doddapaneni, Bhuvana S., Schumann, Canan, Li, Xiaoning, Bracha, Shay, Milovancev, Milan, Alani, Adam W. G., and Taratula, Oleh
Abstract:: Image-guided phototherapy is extensively considered as a promising therapy for cancer treatment. To enhance translational potential of this modality, we developed a single agent-based biocompatible nanoplatform that provides both real time near-infrared (NIR) fluorescence imaging and combinatorial phototherapy with dual photothermal and photodynamic therapeutic mechanisms. The developed theranostic nanoplatform consists...
Resource Type:: Article

Aerobic Bioremediation of PAH Contaminated Soil Results in Increased Genotoxicity and Developmental Toxicity

Creator:: Chibwe, Leah, Geier, Mitra C., Nakamura, Jun, Tanguay, Robert L., Aitken, Michael D., and Simonich, Staci L. Massey
Abstract:: This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by the American Chemical Society and can be found at: https://doi.org/10.1021/acs.est.5b00499
Resource Type:: Article

De novo synthesis of a sunscreen compound in vertebrates

Creator:: Osborn, Andrew R., Almabruk, Khaled H., Holzwarth, Garrett, Asamizu, Shumpei, LaDu, Jane, Kean, Kelsey M., Karplus, P. Andrew, Tanguay, Robert L., Bakalinsky, Alan T., and Mahmud, Taifo
Abstract:: Ultraviolet-protective compounds, such as mycosporine-like amino acids (MAAs) and related gadusols produced by some bacteria, fungi, algae, and marine invertebrates, are critical for the survival of reef-building corals and other marine organisms exposed to high-solar irradiance. These compounds have also been found in marine fish, where their accumulation is thought...
Resource Type:: Article
Full Text:: –12229. doi: 10.1021/ja3041866. Bai L, Li L, Xu H, Minagawa K, Yu Y, Zhang Y, Zhou X, Floss HG, Mahmud T

Evolutionary and Biochemical Studies of C₇-cyclitol Synthases and their Sunscreen Gene Clusters

Creator:: Osborn, Andrew
Abstract:: Sugar phosphate cyclases (SPCs) are enzymes involved in the biosynthesis of many important natural products. SPCs form a unique cyclitol during the early steps in the biosynthesis of many natural products. These natural products include rifamycin, which is chemically modified to rifampicin and used clinically as an antituberculosis drug, and...
Resource Type:: Dissertation

Reversible Covalent Binding of Desferrioxamine B (DFOB) to 2 Polystyrene Microspheres for the Chelation of Aqueous Iron Citrate

Creator:: Touma, Jad G., Kelly, Christine, Coblyn, Matthew, Jovanovic, Goran N., and Schilke, Kate
Abstract:: Desferrioxamine B (DFOB) was reversibly and covalently conjugated to polystyrene microspheres via N-succinimidyl 3-(2-pyridyldithio)propionate (SPDP) crosslinker. DFOB retained post-immobilization activity with at least 89% able to bind Fe(III)-citrate under pH 7.4 and a citrate:iron molar ratio = 100:1. Comparing iron capture by DFOB-activated beads and sulfhydryl (−SH) control beads demonstrated...
Resource Type:: Article
Full Text:: Cite This: https://doi.org/10.1021/acs.iecr.3c00812 Read Online ACCESS Metrics & More Article

Electrochemical Advancement of Solid State Ion Selective Electrodes

Creator:: Bahro, Christopher
Abstract:: The general theme of this dissertation is the development of new analytical sensors to quantitatively study biological and environmental samples in aqueous and non-aqueous environments. A platinum ultramicroelectrode (UME) and a unique carbon-based pH microprobe were used to design a new SECM-based electrochemical bioassay. The Pt UME was used to...
Resource Type:: Dissertation
Full Text:: (22), 13234–13278. https://doi.org/10.1021/acs.chemrev.6b00067. (2) Bard, A. J.; Fan, F. R. F

PetryszakExpressionAtlasUpdateSupplement.pdf

Creator:: Petryszak, Robert, Keays, Maria, Tang, Y. Amy, Fonseca, Nuno A., Barrera, Elisabet, Burdett, Tony, Füllgrabe, Anja, Muñoz-Pomer Fuentes, Alfonso, Jupp, Simon, Koskinen, Satu, Mannion, Oliver, Huerta, Laura, Megy, Karine, Snow, Catherine, Williams, Eleanor, Barzine, Mitra, Hastings, Emma, Weisser, Hendrik, Wright, James, Jaiswal, Pankaj, Huber, Wolfgang, Choudhary, Jyoti, Parkinson, Helen E., and Brazma, Alvis
Abstract:: Expression Atlas (http://www.ebi.ac.uk/gxa) provides information about gene and protein expression in animal and plant samples of different cell types, organism parts, developmental stages, diseases and other conditions. It consists of selected microarray and RNA-sequencing studies from ArrayExpress, which have been manually curated, annotated with ontology terms, checked for high quality...
Full Text:: identification with Mascot Percolator. Journal of proteome research 2009;8;6;3176-81, DOI: 10.1021/pr800982s

A (3-Aminopropyl)triethoxysilane (APTES) and Glutaraldehyde Functionalized Cellulose Surface for Immunoassays

Creator:: Harley, William
Abstract:: The detection of biomolecules is critical for clinical diagnostics but requires specialty labor and high cost. The use of microfluidic paper-based analytical devices (µPADs) for bioassays is simpler and cheaper but has low sensitivity. Improved immobilization of antibodies onto cellulose is demonstrated through surface functionalization with APTES and glutaraldehyde. The...
Resource Type:: Honors College Thesis
Full Text:: /10.1021/ac9013989. (3) Liu, W.; Guo, Y.; Zhao, M.; Li, H.; Zhang, Z. Ring-Oven Washing Technique

In situ mobility of uranium in the presence of nitrate following sulfate-reducing conditions

Creator:: Paradis, Charles J., Jagadamma, Sindhu, Watson, David B., McKay, Larry D., Hazen, Terry C., Park, Melora, and Istok, Jonathan D.
Abstract:: Reoxidation and mobilization of previously reduced and immobilized uranium by dissolved-phase oxidants poses a significant challenge for remediating uranium-contaminated groundwater. Preferential oxidation of reduced sulfur-bearing species, as opposed to reduced uranium-bearing species, has been demonstrated to limit the mobility of uranium at the laboratory scale yet field-scale investigations are lacking....
Resource Type:: Article
Full Text:: . Sci. Technol. 36 (5), 937–942. http://dx.d 10.1021/Es010846i. Bi, Y.Q., Hayes, K.F., 2014a. Nano-FeS

Liquid-gated carbon nanotube transistor noise sources and sensitivity limits

Creator:: Sharf, Tal
Abstract:: Low-dimensional electronic materials offer a platform to observe biological processes with unprecedented spatial and temporal resolution. Carbon nanotubes (CNTs) are the closest physical analog to an ideal 1D system and can be scaled and integrated into multiplexed electronic circuitry. The molecular structure of a CNT is also biocompatible, making them...
Resource Type:: Dissertation
Full Text:: Activity Mapping. Acs Nano 7, 1850-1866, doi:Doi 10.1021/Nn4012847 (2013). 3 Cui, Y., Wei, Q. Q

ScholarsArchive@OSU

Naphthalocyanine-Based Biodegradable Polymeric Nanoparticles for Image-Guided Combinatorial Phototherapy

Aerobic Bioremediation of PAH Contaminated Soil Results in Increased Genotoxicity and Developmental Toxicity

De novo synthesis of a sunscreen compound in vertebrates

Evolutionary and Biochemical Studies of C₇-cyclitol Synthases and their Sunscreen Gene Clusters

Reversible Covalent Binding of Desferrioxamine B (DFOB) to 2 Polystyrene Microspheres for the Chelation of Aqueous Iron Citrate

Electrochemical Advancement of Solid State Ion Selective Electrodes

PetryszakExpressionAtlasUpdateSupplement.pdf

A (3-Aminopropyl)triethoxysilane (APTES) and Glutaraldehyde Functionalized Cellulose Surface for Immunoassays

In situ mobility of uranium in the presence of nitrate following sulfate-reducing conditions

Liquid-gated carbon nanotube transistor noise sources and sensitivity limits

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