Index Catalog // ScholarsArchive@OSU

Transplacental Carcinogenesis with Dibenzo[def,p]chrysene (DBC): Timing of Maternal Exposures Determines Target Tissue Response in Offspring

Creator:: Shorey, Lyndsey, Castro, David J., Baird, William, Siddens, Beth, Lohr, Christiane, Matzke, Melissa, Waters, Katrina M., Corley, Richard A., and Williams, David E.
Abstract:: Dibenzo[def,p]chrysene (DBC) is a transplacental carcinogen in mice (15 mg/kg; gestation day (GD) 17). To mimic residual exposure throughout pregnancy, dams received 4 smaller doses of DBC (3.75 mg/kg) on GD 5, 9, 13 and 17. This regimen alleviated the previously established carcinogenic responses in the thymus, lung, and liver....
Resource Type:: Article
Full Text:: track changes.doc 1 Transplacental Carcinogenesis with Dibenzo[def,p]chrysene (DBC): Timing of

Human in vivo Pharmacokinetics of [¹⁴C]Dibenzo[def,p]chrysene by Accelerator Mass Spectrometry Following Oral Micro-Dosing

Creator:: Madeen, Erin, Corley, Richard A., Crowell, Susan, Turteltaub, Kenneth, Ognibene, Ted, Malfatti, Mike, McQuistan, Tammie J., Garrard, Mary, Sudakin, Dan, and Williams, David E.
Abstract:: Dibenzo(def,p)chrysene (DBC), (also known as dibenzo[a,l]pyrene), is a high molecular weight polycyclic aromatic hydrocarbon (PAH) found in the environment, including food, produced by the incomplete combustion of hydrocarbons. DBC, classified by IARC as a 2A probable human carcinogen, has a relative potency factor (RPF) in animal cancer models 30-fold higher...
Resource Type:: Article

Sulforaphane Regulation of LncRNA in a Transplacental Nrf2 Knockout Mouse Model Exposed to Dibenzo[def,p]chrysene

Creator:: Patel, Karan A.
Abstract:: Dibenzo[def,p]chrysene (DBC) is a highly potent, but less prevalent, environmental carcinogen belonging to a class of compounds known as Polycyclic Aromatic Hydrocarbons (PAHs). They are highly ubiquitous and arise as a byproduct of natural and anthropogenic combustion processes. Previous studies have documented carcinogenic effects upon in utero exposure of PAHs....
Resource Type:: Honors College Thesis
Full Text:: Regulation of LncRNA in a Transplacental Nrf2 Knockout Mouse Model Exposed to Dibenzo[def,p]chrysene

Translational Studies of the High Molecular Weight Polycyclic Aromatic Hydrocarbon, Dibenzo[ def,p] Chrysene; Carcinogenesis and Metabolism

Creator:: Madeen, Erin
Abstract:: The objective of this work is to add to the body of translational data between high dose animal model research and the environmentally relevant human metabolism of the persistent pollutant dibenzo[def,p]chrysene (DBC). We furthered the knowledge of gene/exposure interactions by determining the carcinogenesis risk based on Cyp1b1 genotype following in...
Resource Type:: Dissertation
Full Text:: Aromatic Hydrocarbon, Dibenzo[def,p] Chrysene; Carcinogenesis and Metabolism Abstract approved

Evaluation of collaborative filtering and content based filtering recommenders in jTutors (an online intelligent tutoring system)

Creator:: Appasamy, Bharatwaj
Abstract:: Software engineers often need help with discovering and learning how to use APIs. For example, software engineers who are starting to learn Java, and they want to implement a certain feature in a program, they might want to reuse existing APIs in order to save time versus rewriting it themselves...
Resource Type:: Masters Thesis
Full Text:: : ______________________________________________________ Christopher P. Scaffidi Software engineers often need help with discovering and learning

Ecological Forestry : A Critical Analysis

Creator:: Batavia, Chelsea
Abstract:: Although science is widely accepted as a fundamental source of information underlying decisions about forest management and conservation, considerably less attention has been paid to the inevitable role that normative values and beliefs play in such decisions. This thesis highlights the normative dimensions of "ecological forestry," a strategy of forest...
Resource Type:: Masters Thesis
Full Text:: Abstract approved: ______________________________________________________ Michael P. Nelson

Seasonal concentration, turnover and mode of accumulation of ³²P by the juvenile starry flounder Platichthys stellatus (Pallas) in the Columbia River Estuary

Creator:: Bolen, John Joseph
Abstract:: The seasonal concentration, turnover and mode of accumulation of ³²P by the juvenile starry flounder in Alder Slough, a small eco-system in the Columbia River Estuary, was examined during 1969 and 1970. Levels of ³²P and concentrations of total P were measured to permit computation of specific activities (nCi³²P/g total...
Resource Type:: Dissertation
Full Text:: accumulation of ³²P by the juvenile starry flounder Platichthys stellatus (Pallas) in the Columbia River

Exploring Southeast Asian American Women in Community College Leadership: A Narrative and Life Story Study

Creator:: Vu, Emily P. T.
Abstract:: Background: The numbers of Southeast Asian women in higher education, whether within administration, teaching faculty, or counseling and student services are scarce. The specific needs of minority women go largely unnoticed and remain unaddressed and may contribute to the low numbers of minority women in higher education leadership. Purpose: The...
Resource Type:: Dissertation
Full Text:: experience cultural and linguistic isolation in America’s schools (National Education Association, 2008, p

Cis-2,5-diaminobicyclo[2.2.2]octane : a novel C₂-symmetric scaffold for asymmetric catalysis

Creator:: Shaw, Subrata
Abstract:: This thesis describes the development of a new enantioselective synthetic method employing chiral cis-2,5-diaminobicyclo[2.2.2]octane-based organometallic catalysts. The significance of this new method to organic synthesis is illustrated with preparation of enantioenriched products that are transformed to important pharmaceutical agents. Chapter 1 provides a brief historical overview of asymmetric catalysis, especially...
Resource Type:: Dissertation
Full Text:: characterization of the new salen ligand and its complexes with various transition and p- block metals. Chapter 3

Managing for climate change on federal lands of the western United States: perceived usefulness of climate science, effectiveness of adaptation strategies, and barriers to implementation

Creator:: Kemp, Kerry B., Blades, Jarod J., Klos, P. Zion, Hall, Troy E., Force, Jo Ellen, Morgan, Penelope, and Tinkham, Wade T.
Abstract:: Recent mandates in the United States require federal agencies to incorporate climate change science into land management planning efforts. These mandates target possible adaptation and mitigation strategies. However, the degree to which climate change is actively being considered in agency planning and management decisions is largely unknown. We explored the...
Resource Type:: Article
Full Text:: implementation Kemp, K. B., Blades, J. J., Klos, P. Z., Hall, T. E., Force, J. E., Morgan, P., & Tinkham, W. T

ScholarsArchive@OSU

Transplacental Carcinogenesis with Dibenzo[def,p]chrysene (DBC): Timing of Maternal Exposures Determines Target Tissue Response in Offspring

Human in vivo Pharmacokinetics of [¹⁴C]Dibenzo[def,p]chrysene by Accelerator Mass Spectrometry Following Oral Micro-Dosing

Sulforaphane Regulation of LncRNA in a Transplacental Nrf2 Knockout Mouse Model Exposed to Dibenzo[def,p]chrysene

Translational Studies of the High Molecular Weight Polycyclic Aromatic Hydrocarbon, Dibenzo[ def,p] Chrysene; Carcinogenesis and Metabolism

Evaluation of collaborative filtering and content based filtering recommenders in jTutors (an online intelligent tutoring system)

Ecological Forestry : A Critical Analysis

Seasonal concentration, turnover and mode of accumulation of ³²P by the juvenile starry flounder Platichthys stellatus (Pallas) in the Columbia River Estuary

Exploring Southeast Asian American Women in Community College Leadership: A Narrative and Life Story Study

Cis-2,5-diaminobicyclo[2.2.2]octane : a novel C₂-symmetric scaffold for asymmetric catalysis

Managing for climate change on federal lands of the western United States: perceived usefulness of climate science, effectiveness of adaptation strategies, and barriers to implementation

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