Index Catalog // ScholarsArchive@OSU

Optimizing the Membrane Architecture and Interrogating the Stability of Hybrid Lipid-coated Gold Nanoparticles for Biological Studies and Applications

Creator:: Kmetz-Gonzalez, Gemma
Abstract:: Nanoparticles are a hugely diverse category of material that have a wide variety of biomedical applications, and developing tools for biological research with high cellular uptake is critical to their effective application. However, rarely is attention paid to the exact mechanism by which this is occurring, with most studies focusing...
Resource Type:: Capstone Project
Full Text:: Marilyn R. Mackiewicz* Non-thesis Master’s Final Research Paper Department of Chemistry, Oregon State

Size- and Oxidation-Dependent Toxicity of Graphene Oxide Nanomaterials in Embryonic Zebrafish

Creator:: Lopez, Ryan
Abstract:: Graphene and its derivatives are two-dimensional hexagonal lattices that possess desirable physicochemical properties leading to an ever-expanding list of industrial and biomedical uses. Graphene oxides (GOs) are becoming a popular graphene alternative and while there have been human safety studies, investigations of developmental toxicity are lacking. The use of distinct...
Resource Type:: Masters Thesis
Full Text:: of the scientific writing process. Additionally, I would like to thank Drs. Marilyn Mackiewicz

Alternating Between Amperometric Copper Detection and Potentiometric Calcium Detection on a Carbon-based Ion-selective Electrode

Creator:: Park, Suji
Abstract:: The unique capability of carbon-based ion-selective electrode (ISE) to perform highly sensitive anodic stripping voltammetry, while maintaining all the properties of an ISE, is demonstrated in terms of sensitivity, detection limit, response time and selectivity. Square wave anodic stripping voltammetry involves deposition and dissolution steps of metal ions, which means...
Resource Type:: Masters Thesis
Full Text:: like to thank all committee members, Dr. Marilyn Mackiewicz, Dr. Thomas Sharpton, and Dr. Pankaj

Expanding the Use of 19F NMR Spectroscopy in Per- and Polyfluoroalkyl Substance Analysis: Determination of Total Fluorine and Isomeric Distribution in Aqueous Film-Forming Foams

Creator:: Schaum, Andre F.
Abstract:: Aqueous film-forming foams (AFFFs) are significant sources of per- and polyfluoroalkyl substances (PFAS) in the environment. Current analytical methods that provide quantitative measures of individual PFAS in AFFFs, such as liquid chromatography – tandem mass spectrometry (LC-MS/MS), are often complicated, time-consuming, and expensive. Methods for total fluorine analysis, though quantitative,...
Resource Type:: Masters Thesis
Full Text:: extends to Drs. Kim Anderson, Chris Higgins, and Marilyn Mackiewicz for serving on my committee. A

Experimental and Mathematical Approaches for Overcoming Mass and Heat Transfer Limitations in Cryopreservation of Vertebral Bodies

Creator:: Forcier, Ryan J.
Abstract:: Successful cryopreservation of bone marrow in situ within vertebral bodies offers an opportunity for quick and convenient storage of a significant quantity of bone marrow stem cells, including hematopoietic- and mesenchymal-type stem cells. However, cryopreservation of more complex large tissues and organs, such as the vertebral body (VB), remains problematic....
Resource Type:: Masters Thesis
Full Text:: . Thank you to my committee members: Dr. Morgan Giers, Dr. Lauren Newsom, and Dr. Marilyn Mackiewicz. Dr

Formation of hybrid supramolecular assemblies using biological molecules and transition metals

Creator:: Smith, Rachelle M. S.
Abstract:: Naturally occurring assemblies, such as DNA and proteins, utilize intermolecular forces (i.e H-bonding and van der Waals) to assemble. Utilizing these electrostatic interactions has only just started in the past five decades to be a tool used in synthetic chemistry in what is known as supramolecular chemistry. Supramolecular chemistry has...
Resource Type:: Dissertation

Development of Rapid Diagnostic Tools for Personal Health Monitors in the Context of Therapy Monitoring

Creator:: Wentland, Lael T.
Abstract:: Personal health monitoring tools, a subset of point-of care-diagnostics, enable more frequent testing of chronic health conditions outside of a clinic setting and can inform personalized therapy or support telehealth diagnostic capabilities. While there is evidence that regular monitoring of chronic conditions can lead to better health outcomes and lower...
Resource Type:: Dissertation
Full Text:: capillary size (radius of the tube, r) and hydrophilicity (contact angle, ). Nevertheless, capillary flow

HarperBryanEMTImpactSurfaceLigands.pdf

Creator:: Harper, Bryan, Sinche, Federico, Wu, Rosina Ho, Gowrishankar, Meenambika, Marquart, Grant, Mackiewicz, Marilyn, and Harper, Stacey L.
Abstract:: Gold nanoparticles (AuNPs) are increasingly used in biomedical applications, hence understanding the processes that affect their biocompatibility and stability are of significant interest. In this study, we assessed the stability of peptide-capped AuNPs and used the embryonic zebrafish (Danio rerio) as a vertebrate system to investigate the impact of synthesis...
Full Text:: , Marilyn Mackiewicz 2 and Stacey L. Harper 1,* 1 Department of Environmental and Molecular Toxicology

Eco-corona formation and impact on environmentally relevant micro- and nanoplastics

Creator:: McColley, Campbell J.
Abstract:: Microplastics (MPs) are plastic particles less than 5 mm in diameter. These contaminants are increasingly found in the environment due to increased plastic production, use, and improper disposal. Detecting and measuring these contaminants in the environment has proven difficult, requiring the use of fate and transport models to assess MP...
Resource Type:: Dissertation
Full Text:: in the future. To my graduate committee, Drs. Harper, Baio, Mackiewicz, and Field, thank you for

Elucidating Structure-bioactivity Relationships and Modes of Action of Per- and Polyfluoroalkyl Substance Toxicity in Zebrafish

Creator:: Rericha, Yvonne
Abstract:: Per- and polyfluoroalkyl substances (PFAS) are a broad class of anthropogenic chemicals characterized by highly stable carbon-fluorine (C-F) bonds. PFAS are widely used in industrial and consumer products for their surface-active and stain-resistant properties and are ubiquitously detected in environmental media, biota, and human biomatrices. Although some PFAS are known...
Resource Type:: Dissertation
Full Text:: Field, Dr. Susan Tilton, Dr. Marilyn Mackiewicz, and Dr. Diana Rohlman. My close collaborations with

ScholarsArchive@OSU

Optimizing the Membrane Architecture and Interrogating the Stability of Hybrid Lipid-coated Gold Nanoparticles for Biological Studies and Applications

Size- and Oxidation-Dependent Toxicity of Graphene Oxide Nanomaterials in Embryonic Zebrafish

Alternating Between Amperometric Copper Detection and Potentiometric Calcium Detection on a Carbon-based Ion-selective Electrode

Expanding the Use of 19F NMR Spectroscopy in Per- and Polyfluoroalkyl Substance Analysis: Determination of Total Fluorine and Isomeric Distribution in Aqueous Film-Forming Foams

Experimental and Mathematical Approaches for Overcoming Mass and Heat Transfer Limitations in Cryopreservation of Vertebral Bodies

Formation of hybrid supramolecular assemblies using biological molecules and transition metals

Development of Rapid Diagnostic Tools for Personal Health Monitors in the Context of Therapy Monitoring

HarperBryanEMTImpactSurfaceLigands.pdf

Eco-corona formation and impact on environmentally relevant micro- and nanoplastics

Elucidating Structure-bioactivity Relationships and Modes of Action of Per- and Polyfluoroalkyl Substance Toxicity in Zebrafish

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