Index Catalog // ScholarsArchive@OSU

Blood-based gene expression as a biodosimetry model for neuroblastoma patients treated with ¹³¹I-mIBG

Creator:: Edmondson, David A.
Abstract:: Internal dosimetry is challenging and relies on estimates using MIRD or ICRP biokinetic models. To address this, we looked at gene expression analysis in whole blood from radiotherapy patients. Patients with relapsed or refractory neuroblastoma who received ¹³¹I-mIBG at UCSF were used to correlate internal ionizing radiation (IR) dose with...
Resource Type:: Masters Thesis
Full Text:: : ______________________________________________________ Kathryn A. Higley Internal dosimetry is challenging and relies on estimates using MIRD or

Site specific reference person parameters and derived concentration standards for the Savannah River site

Creator:: Stone, Daniel K.
Abstract:: The U.S. Department of Energy (DOE) Order 458.1 states that the compliance with the DOE annual dose limit of 1 mSv (100 mrem) to a member of the public may be demonstrated by calculating dose to the maximally exposed individual (MEI) or to a representative person. Historically, the MEI concept...
Resource Type:: Masters Thesis
Full Text:: Concentration Standards for the Savannah River Site Abstract approved: Kathryn A. Higley

Development of a dose conversion factor from uptakes of Po-210 through smoking using a modified ICRP 30 lung model

Creator:: Hout, Jason D.
Abstract:: A thesis presented on the determination of factors related to deposition, clearance, and dosimetry of the ICRP 30 lung model as related to smoking. Variations in calculations used to determine radiation doses leave a need to determine a standard method to determine absorbed dose from smoking. Standard parameters are used...
Resource Type:: Masters Thesis
Full Text:: :_______________________________________________ Kathryn A. Higley A thesis presented on the determination of factors

Development and Application of Voxelized Dosimetric Models for Biota : Characterization of the Uncertainty in the International Commission on Radiological Protection's Wildlife Dosimetry System

Creator:: Caffrey, Emily Amanda
Abstract:: A system for radiological dosimetry for nonhuman biota developed by International Commission on Radiological Protection (ICRP) relies on calculations that utilize the Monte Carlo simulations of simple, ellipsoidal geometries with internal radioactivity distributed homogeneously throughout. In this manner it is quick and easy to estimate whole-body dose rates to biota....
Resource Type:: Dissertation
Full Text:: . Abstract approved: ______________________________________________________ Kathryn A. Higley A

A quantitative comparison of cardiovascular imaging systems with respect to the resolution capabilities and the resulting skin entrance doses operating in both fluoroscopic and cine mode

Creator:: Helms, W. Scott
Abstract:: The increasing use of medical procedures using ionizing radiation has increased significantly in recent years. In 1987, the National Council on Radiation Protection Report 93 (NCRP) reported that the average exposure ionizing radiation was 53mRem/year (0.53mSv/year). In their most recent study on radiation exposures NCRP Report 160 in 2009, the...
Resource Type:: Masters Thesis
Full Text:: approved: ______________________________________________________________________ Kathryn A. Higley

Comparison of dosimetric modeling of the International Commission on Radiological Protection trout reference animal

Creator:: Comolli, Michelle LeAnne
Abstract:: Radiation protection has historically been from a human protection approach, therefore many studies have neglected the potential dose contribution from the gastrointestinal tract (GIT) in animal studies. The International Commission on Radiological Protection (ICRP) utilized simplified geometric shapes with Dose Conversion Factors (DCF) based on homogenized models for the trout...
Resource Type:: Masters Thesis
Full Text:: : __________________________________________________________________ Kathryn A. Higley Radiation protection has historically been from a human protection approach

Dose-effects relationships in non-human biota : development of field sampling, dosimetric and analytic techniques through a case study of the aquatic snail Campeloma decisum at Chalk River Laboratories

Creator:: Ruedig, Elizabeth B.
Abstract:: In the last decade regulatory bodies have begun to implement standards to protect populations of non-human biota (NHB) from the consequences of radiation exposure. This is a departure from previous regulatory frameworks which were concerned only with protecting man. The implementation of these new standards has started an ongoing discussion...
Resource Type:: Dissertation
Full Text:: Abstract approved: Kathryn A. Higley In the last decade regulatory bodies have begun to implement

Improvements in the dosimetric models of selected benthic organisms

Creator:: Caffrey, Emily Amanda
Abstract:: The International Commission on Radiological Protection (ICRP) has modeled twelve reference animal and plant (RAP) species using simple geometric shapes in Monte–Carlo (MCNP) based simulations. The focus has now shifted to creating voxel phantoms of each RAP to advance the understanding of radiation interactions in nonhuman biota. The work contained...
Resource Type:: Masters Thesis
Full Text:: Selected Benthic Organisms. Abstract approved: Kathryn A. Higley The International Commission

Dosimetric verification of respiratory gated radiation therapy for tumors involving the lung

Creator:: Webb, Lindsey S.
Abstract:: As the field of radiation therapy evolves new treatment techniques will be established. An example of an evolving treatment technique is respiratory gated radiation therapy (RGRT). Research and studies have shown that RGRT can be used to account for tumor motion as a result of respiratory motion. With evolving technology...
Resource Type:: Masters Thesis
Full Text:: Kathryn A. Higley As the field of radiation therapy evolves new treatment techniques will be

Relative effective dose risk based on medical diagnostic modalities at the Nebraska Medical Center

Creator:: Petrocchi, Michael D.
Abstract:: The use of medical diagnostic imaging involving ionizing radiation has drastically increased in recent years causing concern about possible long term consequences such as the induction of cancer. Recognizing this recent trend, the Institutional Review Board (IRB) at the Nebraska Medical Center commissioned this study in order to determine effective...
Resource Type:: Masters Thesis
Full Text:: the Nebraska Medical Center Abstract approved: __________________________________ Kathryn A

ScholarsArchive@OSU

Blood-based gene expression as a biodosimetry model for neuroblastoma patients treated with ¹³¹I-mIBG

Site specific reference person parameters and derived concentration standards for the Savannah River site

Development of a dose conversion factor from uptakes of Po-210 through smoking using a modified ICRP 30 lung model

Development and Application of Voxelized Dosimetric Models for Biota : Characterization of the Uncertainty in the International Commission on Radiological Protection's Wildlife Dosimetry System

A quantitative comparison of cardiovascular imaging systems with respect to the resolution capabilities and the resulting skin entrance doses operating in both fluoroscopic and cine mode

Comparison of dosimetric modeling of the International Commission on Radiological Protection trout reference animal

Dose-effects relationships in non-human biota : development of field sampling, dosimetric and analytic techniques through a case study of the aquatic snail Campeloma decisum at Chalk River Laboratories

Improvements in the dosimetric models of selected benthic organisms

Dosimetric verification of respiratory gated radiation therapy for tumors involving the lung

Relative effective dose risk based on medical diagnostic modalities at the Nebraska Medical Center

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