Present day data processing technology requires very high speed signal processing and data conversion rates. One such application which requires high speed is switched capacitor circuits used in Sigma-Delta modulators. A major active component of switched capacitor circuits is the monolithic operational amplifier(opamp). Because of the relatively poor speed performance...
High speed serial links are critical components for addressing the growing demand for I/O bandwidth in next-generation computing applications, such as many-core systems, backplane and optical data communications. Due to continued process scaling and circuit innovations, today's CMOS serial link transceivers can achieve tens of Gb/s per pin. However, most...
The release of the IEEE802.15.6 standard has led to increased interest in low-power technologies for wireless body-area-networks (WBANs). The power dissipation, supply voltage, and die area are some of the most important criteria for successful WBAN implementations. Digital-intensive RX architectures can potentially result in sub-1V operation with significant reductions in...
This paper describes methods that can be used to
evaluate stand and tree growth response to a single
application of fertilization and/or thinning with data
collected from multiple installations. Two kinds of
methods were proposed: (1) structure analysis which
applies covariance analysis in a blocked design with and
without sampling...
The goal of this dissertation was to improve our abilities in acquiring critical in vivo data by establishing embryo-larva zebrafish as an exemplary model to quantitatively evaluate cancer progression. The living environment that encompasses a tumor has a significant effect on how cancer develops, grows and metastasizes. In order to...
The diffusion behavior of arsenic (As) and gallium (Ga) atoms from semi-insulating GaAs (SI-GaAs) into ZnO films upon post-growth annealing vis-`a-vis the resulting charge compensation was investigated with the help of x-ray photoelectron spectroscopy (XPS) and secondary ion mass spectroscopy. The films, annealed at 600 °C and 700 °C showed...
Advances in sensor technology are greatly expanding the range of quantities that can be measured while simultaneously reducing the cost. However, deployed sensors drift out of calibration and fail, so every sensor network requires quality control procedures to promptly detect these failures. To address these problems, we propose a two-level...
Soil bacteria are known to be a prolific source of bioactive compounds. They
produce secondary metabolites that can be used as therapeutic agents. This investigation
focused on the chemistry and biology of secondary metabolites from two soil bacteria,
Streptomyces herbaricolor ICBB 9409 and Streptomyces albiflaviniger ICBB 9297,
which were isolated...
Approximately ninety percent of urban Vietnamese households are connected to septic tanks, from which up to three-quarters of the sludge is reported to be dumped into waterways in residential areas. Vietnam has a considerable prevalence of antibiotic misuse and resultant antibiotic-resistant bacteria (ARB) in the human microbiome. Due to the...
My work has focused on using density functional theory to elucidate mechanisms of organocatalytic and transition metal catalyzed reactions by considering competing mechanisms. In each of the three presented studies computational investigation complemented experimental work by predicting stereoselectivity or revealing origins of stereo, regio, or chemoselectivity.
A study on the...
This thesis consists of five chapters: a general introduction, two manuscripts, a collection of published lesson plans, and a general conclusion. The works collected herein are united by the common theme of practical applications in plant breeding. The first manuscript reports a study performed on five malting barley lines grown...
The thermal wave technique has been explored for the use of liquid thermal conductivity measurement and flow property diagnostics in this dissertation. For liquid thermal conductivity measurements, an experimental technique based on the thermal wave approach is developed. A stainless steel strip functions as both a heating element and a...
Successfully predicting an accurate estimated cost is important in the assembly planning process. When designing an assembly plan, an accurate estimation ensures that the proposed plan can be achieved within the predetermined budget. However, achieving an accurate prediction is a challenge since it requires professional judgment, which is dependent upon...
For today’s ubiquitous portable devices, innovative integrated circuits with high performance
yet very low power are necessary. As these devices are used to communicate and sense real world signals in the environment, analog-to-digital converters (ADC) and systems are the key interface circuits needed to digitize the sensed information and they...
Bicyclist safety at urban intersections is a critical element for encouraging an increase in bicycle commuting. With bicycle injury and fatality rates rising due to collisions with vehicles at signalized intersections, increasing the safety of riders continues to be an important consideration when promoting this mode of transportation. Previous research...
Intimate associations with reactive metal species permanently protect soil organic matter (SOM) from microbial access and oxidation, contributing to the build-up of organic carbon (C) stocks in soils. It is increasingly recognized, however, that such associations can be reversible and that reactive metal species might even facilitate the oxidation of...
Treated wood commodities disposed of in landfills contain chemicals that can migrate into the environment. Wood treatments such as ammoniacal copper zinc arsenate (ACZA) contain heavy metals which prevent the biological degradation of wood. These metals can migrate out of treated wood into soil or groundwater, posing environmental hazards. This...
Atomic layer deposition (ALD) is an enabling technique for many new micro- and nanoscale technologies. The self-limiting surface chemical reactions by which ALD fundamentally operates give rise to uniquely high precision (atomic) control over deposited film thickness, uniformity over large areas, and conformality over complex and extreme topographies. One such...
7,7'-Dihydroxy-8,8'-biquinolyl (azaBINOL) was prepared from 7-hydroxyquinoline via N,N-dimethyl O-quinol-7-yl carbamate by directed ortho-metallation followed by FeCl₃-mediated oxidative coupling of the 8-lithioquinoline intermediate. Saponification of the resulting dicarbamate provided crystalline (±)-azaBINOL in 56% overall yield. 6,6'-Bis(dimethylaminocarbonyl)-7,7'-dihydroxy-8,8´-biquinolyl was prepared from the same dicarbamate by a double anionic-Fries rearrangement in 43% yield. 7,7'-Bis(diethylamino-carbonyloxy)-6,6'-diiodo-8,8´-biquinolyl...
The rapid disruption of tropical forests probably imperils global biodiversity more than any other contemporary phenomenon¹⁻³. With deforestation advancing quickly, protected areas are increasingly becoming final refuges for threatened species and natural ecosystem processes. However, many protected areas in the tropics are themselves vulnerable to human encroachment and other environmental...
The induction of drug-metabolizing enzymes is a
complex biochemical process manifested not only by
increases in various cytochrome P-450 isozymes and
related activities, but also by alterations in
endoplasmic reticulum membranes. Little work has been
done to examine how cytochrome P-450 inducing agents
influence other cellular processes, such as
phospholipid...
Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne’s disease, a chronic granulomatous enteritis that plagues domestic and wild ruminants globally. During the silent stages of Johne’s disease, infected animals intermittently shed bacteria for years prior to clinical diagnosis during advanced disease stages. This strategy allows MAP to...
In host-associated microbiomes, the mechanisms that regulate community composition or the principles that govern dynamics remain far from clear. However, understanding how the structure of microbial communities shift as the system moves away from a healthy state is critical to assessing disease progression and to formulate any potential mitigation strategy....
This book is based on a project to completely annotate what is known about the function of the ~150 genes encoded by the genome of the most commonly investigated baculovirus, AcMNPV. Once the annotation was completed (summarized in Chapter 11), the material was organized into a series of chapters integrating...
This book is based on a project to completely annotate what is known about the function of the ~150 genes encoded by the genome of the most commonly investigated baculovirus, AcMNPV. Once the annotation was completed (summarized in Chapter 12), the material was organized into a series of chapters integrating...
This is the third edition of a book that was initiated with the annotation of the function of all the genes in the most commonly studied baculovirus, AcMNPV. The second and third editions involved the update of this information and its integration into chapters covering the major processes central to...
This is the 4th edition of a book that was initiated with the annotation of the function of all the genes in the most commonly studied baculovirus, AcMNPV. It has been almost six years since I reviewed this literature. As a measure of the research that has occurred over this...
Research strongly suggests non-articulation is an effective indication of the reporting quality of both the cash flow statement (Gong et al. 2014) and income statement (Collins et al. 2015). I complete the financial reporting circle by examining the association between non-articulation and the reporting quality of the balance sheet, captured...
Shallow foundations are extensively used to support structures of all sizes and derive their support from near surface soils. Thus, they are typically embedded up to a few meters into the soil profile. Designers of shallow foundations are required to meet two limit states: overall failure of the soil beneath...
Previous research has shown that traveling in a work zone involves a higher risk of crashing compared to normal (non-work zone) driving conditions. Research further suggests that the severity of work zone crashes is greater on average than non-work zone crashes. The period of time in which the traffic control...
Oceanic density overturns are commonly used to parameterize the dissipation rate of turbulent kinetic energy. This method assumes a linear scaling between the Thorpe length scale L[subscript]T and the Ozmidov length scale L[subscript]O. Historic evidence supporting L[subscript]T ~ L[subscript]O has been shown for relatively weak shear-driven turbulence of the thermocline;...
Fish ball is an extruded surimi-based product that is popular among Asian communities. In the manufacturing of fish ball, optimum floatation is extremely important for maximal production. Factors affecting floatation of fish ball in water were investigated. The density of threadfin bream surimi paste significantly decreased (P<O.05) as moisture content...
Early seral forests regenerating from stand-replacing disturbances provide unique habitat for many species in productive, temperate forest landscapes and contribute to supporting biodiversity. Population declines in some species associated with early seral forests have prompted concerns about the conservation of these habitats, particularly the characteristic structural and compositional complexity associated...
While radiocarbon (¹⁴C) abundances in standing stocks of soil carbon have been used to evaluate rates of soil carbon turnover on timescales of several years to centuries, soil-respired ¹⁴CO₂ measurements are an important tool for identifying more immediate responses to disturbance and climate change. Soil Δ¹⁴CO₂ data, however, are often...
There is significant interest in titanium oxide and germanium-silicon oxide nanocomposites for optoelectronic, photocatalytic, and solar cell applications. The ability of the marine diatom Pinnularia sp. to uptake soluble metal oxides from cell culture medium, and incorporate them into the micro- and nano-structure of their amorphous silica cell walls, called...
There is significant interest in the fabrication of nano- and micro-structured silica with spatially ordered features, which exhibit enhanced optoelectronic properties with application to the next generation of display devices, semiconductors, and sensors. Currents methods of fabrication employ top down processes which use extremes of temperature, pressure, and power. There...
Cytoplasmic dynein is an ATP-dependent, microtubule-based molecular motor involved in the positioning and trafficking of cellular cargo. The cargo binding sub-domain of dynein contains the natively disordered intermediate chain (IC) and the homodimeric light chains (Tctex1, LC8 and LC7). The structure and stoichiometry of this complex, how the light chains...
Developmental bisphenol A (BPA) exposure is associated with adverse behavioral
effects, although underlying modes of action remain unclear. Because BPA is a
suspected xenoestrogen, the objective was to identify sex-based changes in adult
zebrafish social behavior developmentally exposed to BPA (0.0, 0.1 or 1 μM) or one of
two control...
Successful pruning relies on accurately identifying the 3D structure of tree branches and leaders. However, this task is arduous in an agricultural setting due to the complexity of scenes, the presence of clutter, and variable weather conditions. This project addresses these challenges by leveraging advancements in 2D image segmentation and...
Foraging behaviors of bumble bee workers have been examined in natural habitats, whereas agricultural landscapes, which can provide insights on flight distances to fragmented patches of bloom, have received limited attention. In particular, information on worker flight distances to crops blooming several months after nests have been established is invaluable....
Zoxamide is the sole β-tubulin inhibitor registered for the control of oomycete pathogens. The current study investigated the activity of zoxamide against Phytophthora sojae and baseline sensitivity was established with a mean EC₅₀ of 0.048 μg/ml. The data is critical for monitoring changes in zoxamide-sensitivity in the field. Three stable...
Full Text:
Ireland, Galway,
Ireland
Reviewed by:
Chao-Xi Luo,
Huazhong Agricultural University,
China
Zhonghua Ma
Global environmental change is causing local extinctions of species. When species depend on one another, as in the mutualistic relationship between plants and pollinators, loss of one interaction partner may cause cascading effects within the community – such as additional extinctions and reduced pollination services. Network theory provides a way...
There has been a tremendous growth in interest in carbon nanodots (C-dots) in the past several years. As a nascent nanomaterial, C-dots have shown great promise in applications that benefit from their superior water dispersibility, low toxicity, non-blinking fluorescent output, chemical and biological compatibility, ease of functionalization and resistance to...
This dissertation addresses gaps of knowledge associated with how ecosystem carbon stocks and greenhouse gas emissions are affected by land use land cover change in tropical peatlands. This was the first study that paired peat swamp forests with oil palm plantations and analyzed site scale variation on greenhouse gas emissions....
Medical professionals experience higher rates of burnout than other professions due to the highly stressful nature of their environment. In 2018, 94 percent of physicians reported experiencing burnout – characterized by emotional fatigue, and feelings of depersonalization and low personal accomplishment – at some point in their careers. As emotional...
Shallow lakes exist in either a clear or turbid state, with the clear state characterized by an abundance of aquatic macrophytes, diverse aquatic biota, low water column nutrients and phytoplankton biomass, whereas the turbid state is characterized by the opposite. These two distinct states are maintained by reinforcing (positive) feedback...
Massive Multiple-User Miltiple-Input Multiple-Output (MU-MIMO) wireless communication systems incorporate promising advanced strong technologies for upcoming 5G communications. To obtain some of the high spectrum and energy e ciencies bonuses brought by MU-MIMO systems, the ability to obtain Channel State information, especially on the receiver side (CSI), is important. To minimize...