The experiments explained in this Honors thesis are focused on finding a cellular model for analyzing Bcl11b, a transcription factor dysregulated in 20% of cases of T-cell Acute Lymphoblastic Leukemia (T-ALL). Acute Lymphoblastic Leukemia is the most common childhood cancer. Because T-ALL is a result of incorrect thymocyte development, research...
Protein secondary structure prediction plays a pivotal role in predicting protein folding in three-dimensions. Its task is to assign each residue one of the three secondary structure classes helix, strand, or random coil. This is an instance of the problem of sequential supervised learning in machine learning. This thesis describes...
High speed and high resolution analog-to-digital converter is a key building block for broadband wireless communications, high definition video applications, medical images and so on. By leveraging the down scaling of the latest CMOS technology and the noise shaping properties, delta-sigma (ΔΣ) ADCs are able to achieve wide-band operation and...
Knowledge workers are struggling in the information flood. There is a growing interest in intelligent desktop environments that help knowledge workers organize their daily life. Intelligent desktop environments allow the desktop user to define a set of “activities” that characterize the user’s desktop work. These environments then attempt to identify...
This study investigates the hydrodynamic characteristics of droplet impinging on heated surfaces using High Speed High Resolution (HSHR) imaging and evaluates the effect of surface temperature and using water and a nanofluid on a polished and a nano-structured surface. Three types of surfaces are used in the
study: polished silicon,...
Simulation has provided much design inspiration for the field of robotics. While many astute ideas can be computationally formulated, there are some good structures in animals that people call “biologically-inspired”. Many robots are designed based on natural creatures such as crabs, spiders, etc. Before we can take full advantage of...
One of the motives of China's Economic Reform is to bring Western
management techniques to China to further economic development. The miraculous
success of the Special Economic Zone (SEZ) in Shenzhen, Guangdong has attracted
many foreign investors who gladly bring their management expertise. This thesis looks
at small, medium and...
A new system called sequential/parallel matrix grammars
for two-dimensional pattern processing is introduced and studied.
Miscellaneous language operations such as union, catenation (row
and column), Kleene's closure (row and column) and substitutions
are investigated. The equivalence of sequential/parallel matrix
languages and finite-turn repetitive checking automata is established.
Hierarchies for both...