Focus is published by Oregon State University College of Forestry. Our goal is to keep Forestry alumni, friends, faculty, staff, and students informed about the College of Forestry and its many activities and programs.
Food waste (FW), brewery waste (BW), and fats, oils, and greases (FOG), are prevalent waste streams in municipalities across the country, particularly in the Pacific Northwest (PNW). Anaerobic digestion (AD), the microbial-mediated transformation of organic waste into methane-rich biogas, offers a sustainable, energy-generating, waste management solution for these wastes. Anaerobic...
The Northern Rubber Boa (Charina bottae) is a small, secretive boa native to the Pacific Northwest. Despite this being possibly the highest latitude boas and one of only two boas native to the continental U.S., it has received surprisingly little attention. Most of the research on the natural history of...
Continental shelf sediments are sinks for dissolved oxygen and sources of many major and minor nutrients required for oceanic surface primary production, resulting in a strong coupling between benthic and pelagic biogeochemical cycling. However, the influence and spatiotemporal variability of benthic remineralization on bottom-water chemistry and the supply of nutrients...
The information in this report is for the purpose of informing cooperators in industry, colleagues at other universities, and others of the results of research in field crops. Reference to products and companies in this publication is for specific information only and does not endorse or recommend that product or...
The California Current Large Marine Ecosystem (CCLME), located on the eastern boundary of the North Pacific Ocean, is highly dynamic, with variable conditions driven by seasonal upwelling, regional oceanography, and broad scale climate patterns. In the last decade, the northeast Pacific Ocean has experienced several marine heatwaves (MHWs), prolonged periods...
There is a growing need for individualized instructional designs in 4-year institutions due to: 1) growing undergraduate enrollment trends across the U.S., 2) broader diversity in students backgrounds, and 3) the growing prevalence of asynchronous remote learning. With the growth in computer technology in education, tools such as adaptive intelligent...
Determining the electrical properties of ceria-based materials is important for their use as electrodes in hot-wall magnetohydrodynamic (MHD) power generators with wall temperatures greater than 1500 ̊C. The electrical conductivity of a material can be used in models for predicting the performance of generator designs. More specifically, the temperature dependent...
Excavations at the Cooper’s Ferry site (10IH73) revealed a long record of repeated human occupation extending from the late Pleistocene into the early Holocene (~16,000-10,000 cal BP) and have yielded unique insights into the Western Stemmed Tradition (WST), which includes. Several studies have focused on WST pit features encountered at...
Oregon's estuaries are important ecosystems for scientific study. Consequently, knowledge of what research has been conducted helps us identify benchmarks and plan new projects. A comprehensive bibliography of published research, technical reports, local documents, and data sets is one means of recording this knowledge. For these reasons, the Guin Library...
Oregon's estuaries are important ecosystems for scientific study. Consequently, knowledge of what research has been conducted helps us identify benchmarks and plan new projects. A comprehensive bibliography of published research, technical reports, local documents, and data sets is one means of recording this knowledge. For these reasons, the Guin Library...
Oregon's estuaries are important ecosystems for scientific study. Consequently, knowledge of what research has been conducted helps us identify benchmarks and plan new projects. A comprehensive bibliography of published research, technical reports, local documents, and data sets is one means of recording this knowledge. For these reasons, the Guin Library...
Oregon's estuaries are important ecosystems for scientific study. Consequently, knowledge of what research has been conducted helps us identify benchmarks and plan new projects. A comprehensive bibliography of published research, technical reports, local documents, and data sets is one means of recording this knowledge. For these reasons, the Guin Library...
Oregon's estuaries are important ecosystems for scientific study. Consequently, knowledge of what research has been conducted helps us identify benchmarks and plan new projects. A comprehensive bibliography of published research, technical reports, local documents, and data sets is one means of recording this knowledge. For these reasons, the Guin Library...
Oregon's estuaries are important ecosystems for scientific study. Consequently, knowledge of what research has been conducted helps us identify benchmarks and plan new projects. A comprehensive bibliography of published research, technical reports, local documents, and data sets is one means of recording this knowledge. For these reasons, the Guin Library...
Oregon's estuaries are important ecosystems for scientific study. Consequently, knowledge of what research has been conducted helps us identify benchmarks and plan new projects. A comprehensive bibliography of published research, technical reports, local documents, and data sets is one means of recording this knowledge. For these reasons, the Guin Library...
Autonomous robotic agents are on their way to becoming in-home personal assistants, construction assistants, and warehouse workers. The degree of autonomy of such systems is reflected by the manner in which we specify goals to them; the abstraction of low-level commands to high-level goals goes hand-in-hand with increased autonomy. In...
The utility of high-throughput, computational screening has become an invaluable asset to the field of materials science. In the hierarchy of computational methods, the most accurate methods are often the most computationally expensive. However, as both the efficiency and fidelity of numerical techniques advance, high-quality screening of large materials datasets...
Long-term, large-scale studies of meta-ecosystems provide critical information about how global change influences communities. In my dissertation, I analyzed data from studies encompassing 18 years (2006 – 2023) and over 1,000 km of coastline to investigate drivers of rocky intertidal community structure and dynamics. Specifically, I explored the roles of...
Healthcare access exhibits differing levels of complexity, often requiring multi-disciplinary approaches to study its barriers and enablers. Though Argentina has achieved nominal universal healthcare coverage through its public healthcare system, full effective coverage has not been achieved. The public system also has a parallel private care system, adding further complexity...
Anthropogenic induced climate change is predicted to alter distribution of existing plant populations. As plants migrate over space and time, populations often fragment and contract, affecting basic elements of population dynamics (e.g., population size, gene flow, genetic diversity, etc.). Little is known, however, how these impacts on plant species will...
A secret sharing scheme allows a dealer to distribute a secret with a set of parties, such that only a certain subset of parties can collaborate and learn the shared secret. Traditional secret sharing schemes have been used as building blocks in various subdomains of cryptography. Recently, two new extensions...
Studies of Hawaiian volcanoes contribute valuable insights about Earth processes and mantle evolution, and are fundamental for understanding the construction of the largest volcanoes on terrestrial planets. The pre-shield stage exists in every Hawaiian volcano, but is usually blanketed by high volume tholeiitic lava flows during the main shield stage....
As global atmospheric carbon emissions continue to rise, scientists and land managers are increasingly looking to natural ecosystems to sequester and store carbon to buffer the impacts of climate change. Despite their small geographic size, many coastal ecosystems such as salt marshes, seagrass meadows, and mangroves sequester large amounts of...
Toxin production by cyanobacterial harmful algal blooms (cyanoHABs) in freshwater systems has lasting ecological and human impacts. Nutrients, light availability, hydrology, and microbial community composition impact the frequency and intensity of toxic cyanoHABs. Climate change will exacerbate toxic cyanoHABs, making real time and predictive monitoring a vital tool for managing...
Pacific walrus (Odobenus rosmarus) are particularly vulnerable to the impacts of climate change due to the high reliance on sea ice for safety, transport, and social behaviors. Additionally, the walrus diet consists of predominantly bivalves, whose populations are in decline as a result of ocean acidification. We first determined the...
Secure Computation is a powerful tool that enables a set of parties to jointly compute any function over their private inputs, without a trusted third party. Private Set Intersection is a specific case of two-party Secure Computation, where Alice (with private set X) and Bob (with private set Y) specifically...
The purpose of this study was to explore and describe how the orientations and knowledge of linguistically responsive teaching, as well as personal characteristics of school-based agriculture education (SBAE) teachers, influence the frequency of their implementation of linguistically responsive practices. Grounded in the Linguistically Responsive Teaching framework by Lucas and...
Unintended pregnancy has been found to be one of the most prominent challenges that the public health system is forced to overcome due to the financial and social burdens that accompany it (Yazdkhasti et al., 2015). With nearly 48% of reproductive-age American female patients having experienced at least one unintended...
Natural resources are essential to humanity. With the increase in global development in recent decades, people must monitor the state of the environment, whose disturbance has a more significant impact on society than before. However, conventional environmental monitoring is challenged in highly dynamic ecosystems and large areas. As a solution,...
The advancement of artificial intelligence (AI) has led to transformative developments across multiple sectors, fostering innovation and redefining our interactions with technology. As AI matures and becomes integrated into society, it offers numerous opportunities to address global challenges and revolutionize a wide array of human endeavors. These advances are driven...
This dissertation consists of three essays that provide comprehensive insights into the complex dynamics shaping entrepreneurial and organizational outcomes. In the first essay I incorporate the Biophilia Hypothesis and the Challenge Hindrance Stressor framework to study entrepreneurial creativity. The findings emphasize the importance of more frequent nature visits for entrepreneurs...
This dissertation develops a framework for Curandera feminism, informed by familial healing practices, women of color feminisms, and institutional critique. My research centers my family’s generational Curandera practices. As I honor the call to be critical of the master’s tools, I seek possibilities for institutional change through Curandera feminism. Institutions...
The body of work aims to contribute to the area of Quantitative analysis in Environmental Sciences, and is focused on the microbiome. The underlying theme for the dissertation is methods and workflow. The unique bioinformatics workflow used for the analysis of genomic data was used to answer distinct and pressing...
The Columbia River Gillnetter is the pilot of the Lower Columbia River commercial fishing industry, keeping fishermen and the public in touch with today's important issues.
The Columbia River Gillnetter is the pilot of the Lower Columbia River commercial fishing industry, keeping fishermen and the public in touch with today's important issues.
The field of toxicology is challenged with a vast number of environmental chemicals and mixtures to which humans and ecosystems are exposed with limited toxicity data available. Chemical hazard assessment traditionally utilizes mammalian models and can be both cost- and time-limiting and may pose ethical concerns. To rapidly tackle this...
The Community Action Partnership of Oregon (CAPO) approached Oregon State University to assist in developing statewide indicators which help local agencies better utilize data for continuous improvement. The project was expanded to include Washington and Idaho. This report summarizes the project's findings.
Drought can have substantial negative effects on human health, creating challenges for public health departments, emergency managers, and healthcare providers. For example, drought can lead to decreased water quantity and quality, increased incidence of illness or disease, increased mortality rates, and adverse mental health outcomes, especially as livelihoods are affected....
The group of scientists that make up the Intergovernmental Panel on Climate Change found in 2007 that the warming of Earth’s climate is unequivocal and largely due to human activity. Earth’s climate has changed in the past, though the recent magnitude and pace of changes are unprecedented in human existence....
Connectivity of fish populations is a crucial question for fisheries conservation and the development of spatial management plans. Both adult and larval movement define the extent and direction of ecological and evolutionary overlap between geographic regions and, therefore, how we define stocks for management purposes. Within that context, my work...
Daily cyclical changes of light are brought on by the axial rotation of the Earth while seasonal changes in light are caused by Earth’s tilt as it revolves around the sun. Major life history traits, such as development, which are tied to metabolic processes, have a strong link to the...
Meditation research in recent decades has disproportionately focused on the Buddhist derived practice of “mindfulness” meditation while leaving most other Buddhist meditation practices unstudied. The current study seeks to remedy this homogeneity through the adaptation of a novel meditation practice used in Tibetan Buddhism to affect motivation. We explored traditional...
At a time when environmental conditions are rapidly changing, understanding how thermal extremes impact wildlife is imperative to fully understanding the consequences of climate change in natural ecosystems. While many organisms are currently impacted by rapidly warming and more erratic environmental conditions, identifying and investigating model species whose life histories...
Human-animal relationships, emerging as an aftermath of human-animal interactions, have been increasingly investigated in recent years. It is possible to see the results of the effects of these relationships on both human and animal welfare. This study predicted that caretakers with hands-on contact with their zoo animals would have significantly...
The focus of this thesis is to design, characterize, and apply novel computational methods and molecular systems to interrogate heterogeneous human gut microbiome-related phenomena. In Chapter 2, I design, implement, and characterize a method for embedding co-occurrence patterns derived from massive 16s amplicon datasets. I use this method to 1....
Most of the concrete in the world is produced using hydraulic cement (ordinary portland cement, OPC) and siliceous or alumino-siliceous supplementary cementitious materials (SCM). Due to the shift in focus toward environmental sustainability within the construction industry, alkali-activated cementitious systems (AAC) have gained significant attention to reduce the carbon footprint...
Characterization of uranium isotope compositions is of great interest in many nuclear sub-areas for safeguards purposes. Reprocessing facilities utilizing pyroprocessing raised an issue of uranium isotope monitoring due to the difficulty to apply traditional approaches under extreme environments. An rapid and remote method to characterize uranium isotope compositions for such...
The rates of biological introductions and invasions are increasing, driving up the associated harms to ecosystems and economies. The spread and effects of invasive organisms depend on the specifics of the introduction, the character of the invaded ecosystem, and multiple traits of the invasive organism itself. One mechanism by which...
Metallic glasses (MGs), also called amorphous metals, are metals or metallic alloys trapped in a disordered glassy state. Their amorphous nature and absence of features such as crystal lattices and defects (dislocations, grain boundaries etc.) endows them with a host of properties that far surpass those of common crystalline materials....
This research presents a u-channel based study of the natural remanent magnetization (NRM), the laboratory magnetization, Anhysteretic Remanent Magnetization (ARM), and magnetic susceptibility (k), from the upper 100 m of International Ocean Discovery Program (IODP) Expedition 383 Site U1543 in the eastern South Pacific sector of the Southern Ocean. Alternating...
Engineering education research has led to a greater understanding of the gap in preparedness of students for the engineering industry. Multiple studies comparing the workplace and academic contexts and the participants in those contexts (i.e., students, faculty, and engineering practitioners) have emphasized similarities and differences between the two contexts by...
Hop (Humulus lupulus L. var. lupulus) is a diploid, dioecious plant with an extensive history of cultivation and use in brewing, as a textile, and for its therapeutic properties. Hop is prized for its ability to produce a variety of aromatic and flavor compounds, as well as compounds with anti-microbial...
Issues of injustice in society (e.g. racism, classism, sexism, ableism) are perpetuated in and through educational opportunities, including mathematics learning (Freire, 1970/2000). Those that are committed to disrupting the interlocking systems that create disparities and oppression in mathematics education are considered to be “pursuing justice.” Pursuit of justice can involve...
Reinforcement learning has emerged as a popular tool for solving control tasks, with multiple works focusing on the complex and dynamic task of locomotion. However, the naive application of reinforcement learning to this problem often produces maladaptive policies that exploit the model or reward function. This results in behavior that...
Coral reefs form vast ecosystems in tropical oceans that are hotspots for biodiversity and are economically valuable. The ecological success of coral reefs is made possible by the symbiotic relationship between corals and dinoflagellate algae from the family Symbiodiniaceae. In this symbiosis, the algae are found within host gastrodermal cells...
Metallic nuclear fuels have long been studied for use in advanced nuclear reactors, with efforts invested in improving the viability of metallic nuclear fuel elements and overall safety of advanced reactor design concepts. During reactor operations, fuel forms undergo restructuring due to a variety of physical phenomena. Expansion of the...
Systems biology is a powerful approach which considers and sheds light on all of the puzzle pieces which make up complex biological processes, and is an effective alternative to unraveling these processes using traditional molecular approaches alone. It is a natural companion approach for computational biology, which leverages the power...
When observers monitor for infrequent signals for extended durations, they generally experience a decline in detections over time. This decline is termed the vigilance decrement. Current theories of vigilance attribute the decrement to three potential mechanisms: conservative shifts in response bias, losses of sensitivity, and an increased rate of attentional...
This thesis builds on a modeling tool that has been developed to link thermodynamic modeling and concrete performance. This tool is intended to predict the performance for modern concrete mixtures made with ordinary portland cement (OPC), conventional and novel supplementary cementitious materials (SCMs), and limestone (Ls). The first part of...
College students today have a lot to contend with in their journey as young adults. The college years are often a transitional time for students, and as such there is a vulnerability to mental health declines. Financial, academic, and social strain are some of the factors that can contribute to...
Continental margin sediments have been recognized as a major source of dissolved iron to the global ocean. The focus of this study was to build an early diagenetic model that can be used to simulate iron fluxes from continental margins and thereby identify key controlling factors. The model uses the...
Climate change presents multiple stressors that are impacting marine life. As carbon dioxide emissions continue to increase in the atmosphere, atmospheric and sea water temperatures increase. In addition, more carbon dioxide is absorbed into the oceans, reducing pH and aragonite saturation state, resulting in ocean acidification (OA). Tightly coupled with...
Exposure assessment is necessary to determine the frequency and magnitude of environmental contaminants, especially since exposure may lead to adverse health outcomes. Traditional personal exposure assessment tools such as biological samples are limited in their ability to capture a wide range of chemical exposures from a single sample, and others...
Much of our knowledge about transgender (folks who identify as not cisgender) lives in universities centers around barriers experienced, feelings of exclusion, and being victims of harassment and violence. This thesis describes conversations regarding captured gender euphoric moments from five students at a large university. They came together through a...
Dysferlin is a ∼230 kDa terminally anchored membrane protein that is ubiquitously expressed, but is particularly enriched in skeletal and cardiac muscle tissue. Mutations covering the length of the protein have been linked to muscle wasting diseases including limb-girdle muscular dystrophy and Myoshi myopathy. Dysferlin has been shown to play...
With the rapid advancement of educational technology and the need for personalized, engaging content to accommodate diverse learning needs, Virtual Reality (VR) holds promises for the present and future. However, VR applications suffer from challenges, including usability concerns, lack of pedagogical value, and evaluation standards. This thesis focuses on two...
Much like wind energy in its early years, marine energy has vast potential, and wave energy converter (WEC) concepts are constantly in development. Consequently, wave energy faces many challenges for expansion and has a wide-ranging design space of WEC concepts. The large design space demands new methods for understanding the...
Animals aggregate and interact in nonuniform and nonrandom patterns, which lead to group level characteristics that have important evolutionary and ecological consequences. Network analysis provides a useful conceptual framework for linking animal interactions at all scales from dyads to communities, to populations and ecosystems. Despite exciting theoretical and applied advances...
Phytoplankton initiate the marine carbon cycle by fixing carbon dioxide into biologically available compounds. These abundant single celled organisms mediate carbon flux from the atmosphere to the deep ocean and are the base of the marine food web, supplying new carbon to higher trophic levels. Phytoplankton are highly diverse and...
The rapid pace of climate change is increasing tree mortality and highlighting the need to improve the mechanistic understanding of plant function under increased water stress. However, the processes that control soil moisture availability in steep mountainous terrain are poorly understood, as are the relative effects of atmospheric and soil...
Kelps are large brown algae in the order Laminariales and are foundation species that form the basis of kelp forests. Present across a quarter of the world’s coastlines, kelp forests provide diverse services to coastal communities, as habitat for commercially and culturally important species, as a food source for humans...
Using data collected from cannabis growers and traditional farmers, and the “Good Farmer” approach, this research provides a comparative analysis of the occupational identities of cannabis cultivators and traditional farmers in Colorado and Oregon. Though both growers and farmers within the study suggested that cannabis cultivation differed from conventional agriculture,...
Messenger RNA (mRNA) therapy has massive potential to treat various genetic disorders by providing effective proteins to the diseased cells and tissues. Its therapeutic applications include protein replacement, genome editing, and immunotherapy. For successful mRNA treatment, mRNA must be delivered to the cytosol of target cells. One of the leading...
Beginning in 2020, the SARS-CoV-2 pandemic contributed to an increase in housing insecurity among college students. As awareness around homelessness has increased, so has research aimed at better understanding the causes of homelessness and housing insecurity among college students, as well as opportunities to better support economic access to higher...
Wine taste and mouthfeel are essential factors that determine consumer acceptance, consumer preference, and wine quality. The three taste descriptors, sweet, sour, and bitter, are well understood and routinely appearing in wine sensory. In contrast, information related to mouthfeel sensations is still relatively limited. Winemakers have worked hard to craft...
Environmental archives provide records of natural and anthropogenic variation in the environment at different temporal and spatial scales. Lead (Pb) concentrations and isotopic ratios are useful tracers of anthropogenic emissions from industrial activities including mining, smelting, and leaded gasoline use, however, methods of measuring Pb are largely limited in low...
Agriculture teachers, in comparison to other high school teachers, work in more varied and demanding work environments (Terry & Briers, 2010; Torres, Ulmer, & Aschenbrener, 2008). The body of literature studying the impacts of more varied and demanding work environment on early career agriculture teachers (ECATs) is commonly limited to...
Gamma Ray Bursts (GRBs) are the most energetic explosions in the Universe, producing up to $\sim10^{53}$ ergs of energy in the first few seconds of their emission -- the so-called prompt phase that is dominated by high energy X-ray and $\gamma$-ray photons. The very large luminosities released in these events...
Magneto- and chemostratigraphic correlation underpins much of our understanding of Earth history, yet typical correlation techniques are neither quantitative nor objective. Within this dissertation, I detail my efforts to develop and apply dynamic programming-based algorithms that accomplish optimal and reproducible stratigraphic alignment. I apply these algorithms to three geologic intervals:...
The most common test methods to evaluate alkali-silica reaction (ASR), the concrete prism test (CPT) and the accelerated mortar bar tests (AMBT), have limitations and are not entirely reliable in terms of predicting the performance of concrete with prevention measures under field conditions. In this study, the miniature concrete prism...
Recent interest in oxy-fuel combustion for carbon capture, as well as advancements in technologies such as magnetics, materials, and computational modeling has sparked renewed interest in magnetohydrodynamic (MHD) power generation. The increased temperatures of oxy-fuel combustion versus air-fuel combustion poses a challenge in the selection of materials for plasma exposed...
Immobilized proteins are integral components of a number of important technologies, including the principal component of many biosensors, as functional coatings in various implants, as catalysts is industrial biosynthesis, and as the building blocks of next-generation nanotechnologies. Despite their ubiquity, relatively little is known about the processes that shape immobilized...
Dietary nitrate (NO3-), consumed primarily from leafy green and root vegetables, lowers blood pressure, improves vascular function and aerobic exercise performance. This performance-enhancing effect of nitrate supplementation is largely attributed to the increased bioavailability of the signaling molecule, nitric oxide (NO). Nitric oxide is a ubiquitous free radical signaling molecule...
Prototyping is a crucial step in product design and development, but it is also known as the highest sunk cost. The top 20 Research and Development (R&D) department spends 142 billion dollars, yet 40 to 46 percent of this money goes into developing products that cannot even make to the...
Aggregation equations have been used to model phenomena such as insect swarming and chemotaxis. Previous work on aggregation equations in the area of analysis applied to PDE has proven well-posedness of certain classes of aggregation equations in Lebesgue spaces. We will prove local existence of solutions in H^1 to an...
Milk is the first source of nutrition for all mammalian neonates. The complex matrix that constitutes milk has evolved to provide optimal nutrition for the newborn, for each species, respectively. Milk fat, originating in mammary epithelial, forms lipid droplets which are stabilized in the aqueous environment by bioactive polar lipids...
Previous research on academic success in biology has focused on the influence of prerequisite knowledge and cognitive ability as measured by course grades or GPA. More recently, the field has considered the influence of non-cognitive factors such as grit, defined as passion and perseverance for long term goals. Both grit...
Obesity is a complex multifactorial disease resulting from excessive energy intake compared to energy expenditure. The excess energy is mostly stored as fat in enlarged adipocytes, but some lipids may infiltrate other organs such as the liver to form ectopic fat. Adipose tissue and ectopic fat produce and secrete a...
Modern product design drives the boundaries of innovation by encompassing complex Design-for-X objectives, and the inclusion of multidimensional stakeholders. This growing complexity in product design has left design teams unequipped, as classical design theory is bounded by designer experience, expertise, and cognition. One novel approach to tackling product complexity is...
Society derives many critical and irreplaceable values from forests. With a growing global human population and rates of consumption, forests are under increasing pressure to provide all these values simultaneously. To meet societal demands for wood products, tree plantations are becoming increasingly common and are replacing native forests. Yet, forests...
The phases of transition alumina are scientifically interesting due to their high specific surface area, favorable acid/ base characteristics, and chemical and hydrothermal stability which make this metallic oxide a prime candidate for use as a support for metallic nanoparticles (NPs) in heterocatalysis. Interactions at alumina/Pt interfaces are important for...
Most operating power reactors use oxide fuel in the form of uranium oxide (UO2) which is robust against high temperatures but suffers from poor mechanical performance at high levels of burnup. Currently, the maximum average burnup in light water reactors in the US is 62.5 GWd/t, which is partially imposed...
The purpose of this dual-manuscript dissertation is to assess and synthesize the current body of qualitative literature on the topic of the experience of counselor trainees as participants in experiential groups. The first manuscript is presented in Chapter 2. In this study, I performed a directed content analysis on 15...
The end goal of any educational program is to prepare a student for the challenges they will see after completion of their studies. In the realm of engineering, the pinnacle of this occurs during a student’s final Capstone course series, where students are asked to apply their various skills learned...
Generally presented as a preferred social norm based on both ethical considerations and legislative demands, gender equality has been highly encouraged in recent years. For instance, The United Nations Sustainable Development Goals for 2030 call out achieving gender equality and empowerment of women. However, although there are multiple efforts to...
Xanthohumol, a prenylated flavonoid found in hops and beer, possesses a long-standing reputation to improve health. Xanthohumol’s cytotoxicity to a wide variety of cancer cell lines is well-established. Herein we provide further insight into the cytotoxicity of not only xanthohumol, but also its non-estrogenic derivatives, to a number of colonic...
Vitamin E (VitE) is necessary for vertebrate embryonic development. VitE prevents lipid peroxidation (LPO), which requires detoxification by cellular antioxidant systems subsequently involving reducing power derived from energy metabolism. Thus, VitE protects metabolic networks in the developing embryo and the integrated gene expression networks compensating for and impaired by LPO-induced...
We describe a series of novel computational models, CERENKOV (Computational Elucidation of the REgulatory NonKOding Variome) and its successors CERENKOV2, CERENKOV3, and Convolutional CERENKOV3, for discriminating regulatory single nucleotide polymorphisms (rSNPs) from non-regulatory SNPs within non-coding genetic loci. The CERENKOV models are designed for recognizing rSNPs in the context of...