Clostridium perfringens is the causative agent of a wide variety of diseases in animals and humans. C. perfringens can produce more than 15 toxins. However, individual strains produce a subset of these toxins. Although a small percentage of C. perfringens isolates (mostly belonging to type A) produce C. perfringens enterotoxin...
Clostridium perfringens type A is the causative agent of a variety of histotoxic and enteric diseases. The ability of C. perfringens spores to germinate in vivo might be due to the presence of nutrient germinants in the host tissue and blood. In the current study, we investigated the ability of...
Clostridium difficile is the causative agent of the majority of antibiotic associated diarrheas. C.
difficile spores are recognized as the morphotype of transmission, infection and persistence.
However, there is a lack of knowledge on how C. difficile spores interact with the host’s
epithelial surfaces. In this context, we have characterized...
High hydrostatic pressure (HHP) is the most-widely adopted novel non-thermal technology for the commercial pasteurization of foods. However, HHP-induced inactivation of bacterial spores remains a challenge due their resistance to the treatment limits of currently available industrial HHP units (i.e., ~650 MPa and 50°C). Several reports have demonstrated that high...
Clostridium difficile´s presence has been reported in meat products stored typically at low temperatures. This study evaluated the viability in phosphate buffer saline (PBS) of spores from epidemic C. difficile strain R20291 (4.6 log CFU/ml) and M120 (7.8 log CFU/ml). Viability was assessed during 4 months at -80°C, -20°C, 4°C...
English: Clostridium difficile is an emerging anaerobic, spore forming pathogen, recognized as the etiological agent of ~ 30% of antibiotic associated diarrheas. Clinical symptoms can fluctuate from mild to moderate diarrhea, pseudomembranous colitis and toxic megacolon. The incidence of C. difficile associated infections (CDAI) is ~ 1% of total hospitalized...
Consumer demand for improved-quality and fresh-like food products have led to the development of new non-thermal preservation methods. High pressure processing (HPP) is currently the novel non-thermal technology best established in the food processing industry. However, many potential HPP applications would require long treatment times to ensure an adequate inactivation...
Sporulation is an important strategy for certain bacterial species within the phylum Firmicutes to survive longer periods of time in adverse conditions. All spore-forming bacteria have two phases in their life; the vegetative form, where they can maintain all metabolic activities and replicate to increase numbers, and the spore form,...
Background: Clostridium difficile is the main cause of nosocomial infections including antibiotic associated diarrhea, pseudomembranous colitis and toxic megacolon. During the course of Clostridium difficile infections (CDI), C. difficile undergoes sporulation and releases spores to the colonic environment. The elevated relapse rates of CDI suggest that C. difficile spores has...
The most frequent cause of pseudomembranous colitis is Clostridium difficile (C. difficile) infection. This type of colitis is characterized by an endoscopic pattern of numerous small, yellowish or whitish plaques diffusely distributed, which typically compromises the rectum extending to proximal colon. Occasionally, the pseudomembranes compromise only the transverse or right...
A beta Poisson dose-response model for Vibrio vulnificus food poisoning cases leading to septicemia was used when evaluating the effect of 15°C depuration on the estimated risk of raw oyster consumption. Statistical variability sources included V. vulnificus load at harvest, time and temperature during harvest and transportation to processing plants,...
The increased severity of Clostridium difficile infection is primarily attributed to the appearance of an epidemic strain characterized as PCR ribotype 027. The only report that identified epidemic C. difficile ribotype 027 in an American country outside of North America comes from Costa Rica, raising the possibility that strains 027...
Clostridium difficile is an important nosocomial pathogen that has become a major cause of antibiotic-associated diarrhea.
There is a general consensus that C. difficile spores play an important role in C. difficile pathogenesis, contributing to infection,
persistence, and transmission. Evidence has demonstrated that C. difficile spores have an outermost layer,...
Phaseolus vulgaris, the common bean, is susceptible to many
bacterial, fungal and viral diseases. However, resistance to several
diseases has been identified in related Phaseolus species, P.
coccineus, P. acutifolius and P. lunatus. Thus, interspecific
hybridization could result in transfer of beneficial characteristics.
One of the problems encountered in interspecific...
Chlamydia trachomatis is an obligate intracellular bacterium that causes diseases of the eye and urogenital tract in humans. It is the cause of the sexual transmitted infection (STI) chlamydia, the most prevalent STI worldwide, and the ocular disease trachoma, the leading cause of infectious blindness. To date there is no...
This dissertation investigates the microbial diversity and factors influencing the assembly of microbial communities in kombucha production, using a combination of 1H Nuclear Magnetic Resonance Spectroscopy, 16S and ITS rRNA metabarcoding, and traditional culture-based microbiological methods. It also explores the diversity of kombucha starter cultures through shotgun sequencing and metabarcoding...
1. Foraging and migration often require different energetic and movement strategies. Though not readily apparent, constraints during one phase might influence the foraging strategies observed in another. For marine birds that fly and dive, body size constraints likely present a trade-off between foraging ability and migration as smaller bodies reduce...
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of thick-billed
murres in the Bering Sea
Orben, R. A., Paredes, R., Roby, D. D., Irons, D. B
1. Foraging and migration often require different energetic and movement strategies. Though not readily apparent, constraints during one phase might influence the foraging strategies observed in another. For marine birds that fly and dive, body size constraints likely present a trade-off between foraging ability and migration as smaller bodies reduce...
1. Foraging and migration often require different energetic and movement strategies. Though not readily apparent, constraints during one phase might influence the foraging strategies observed in another. For marine birds that fly and dive, body size constraints likely present a trade-off between foraging ability and migration as smaller bodies reduce...
Wheat stripe rust (WSR), also called yellow rust of wheat (Tricitum spp.), causal agent Puccinia striiformis f.sp. tritici (Pst), is a foliar disease of major economic importance on wheat, especially grown in temperate locations. WSR causes major losses of wheat yield, estimated at nearly $ 1 billion per year, and...
Water is an absolute necessity for life as we know it. It provides a useful medium in which chemical reactions take place that allowed for the development of single cellular organisms. When combined with the evolutionary accident that was pho- tosynthesis, water became not only a useful medium chemical reactions,...
Fluid-structure interaction (FSI) has been of significant research interest worldwide over the past several decades because of its variety of applications in both offshore and coastal engineering. Researchers analyzing FSI systems rely heavily on experimental tests in model scale in laboratories or large-scale sea trials. However, these tests are often...
Clostridium perfringens type A strains are one of the main causative agents of gastrointestinal (GI) diseases in human and can cause both food poisoning (FP) and non-food-borne (NFB) diseases. Several factors contribute to the pathogenesis of C. perfringens type A strains including the wide presence of C. perfringens spores with...
C. perfringens type A isolates are the causative agents of C. perfringens type A food poisoning (FP) and non-food-borne (NFB) human gastrointestinal diseases. In this study, we evaluated the antimicrobial effect of essential oil constituents (cinnamaldehyde, eugenol, allyl isothiocyanate (AITC), and carvacrol) against C. perfringens FP and NFB isolates grown...
The enterotoxin-producing Clostridium perfringens type A isolates are responsible for the third most common foodborne illness in the United States and can also cause non-foodborne human gastrointestinal (GI) diseases such as antibiotic- associated and sporadic diarrheas. Three important factors contribute to the ability of C. perfringens to cause GI diseases,...
C. perfringens is a Gram-positive, spore-forming, anaerobic pathogenic
bacterium capable of causing a wide variety of diseases in both humans and animals.
However, the two most common illnesses in humans are C. perfringens type A food
poisoning (FP) and non-food-borne (NFB) gastrointestinal (GI) illnesses . These two
major diseases are...
AIM: Species that breed sympatrically often occupy different foraging niches to
mitigate competition for prey. When resource availability declines at the end of
the breeding season, some animals migrate to regions with more favourable
environmental conditions. When these life-history traits combine, foraging
habitat preferences may continue to influence migration patterns...
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during their non-breeding migrations
Rachael A. Orben, David B. Irons, Rosana Paredes, Daniel D
AIM: Species that breed sympatrically often occupy different foraging niches to
mitigate competition for prey. When resource availability declines at the end of
the breeding season, some animals migrate to regions with more favourable
environmental conditions. When these life-history traits combine, foraging
habitat preferences may continue to influence migration patterns...
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migrations
Orben, R. A., Irons, D. B., Paredes, R., Roby, D. D., Phillips, R. A., & Shaffer, S.
A. (2015
AIM: Species that breed sympatrically often occupy different foraging niches to mitigate competition for prey. When resource availability declines at the end of the breeding season, some animals migrate to regions with more favourable environmental conditions. When these life-history traits combine, foraging habitat preferences may continue to influence migration patterns...
Clostridium perfringens is a spore-forming pathogenic bacterium that causes a variety of diseases in human and animals. C. perfringens type A isolates produce enterotoxin (CPE) causing food poisoning (FP) and non-food-borne (NFB) gastrointestinal (GI) diseases including antibiotic-associated diarrhea and sporadic diarrhea. C. perfringens type A food poisoning currently ranks as...
Clostridium perfringens is a spore-forming anaerobic organism that is commonly present in fresh meat and poultry. The organism's spores can survive a range of food processing methods. C. perfringens type F isolates are the causative agents of C. perfringens type F food poisoning (FP) and non-food borne (NFB) human gastrointestinal...
C. perfringens is a spore-forming, gram-positive, anaerobic pathogenic bacterium capable of causing a wide variety of diseases in both humans and animals. However, the two most common illnesses in humans are C. perfringens type A food poisoning (FP) and non-food-borne (NFB) gastrointestinal (GI) illnesses. Interestingly, these two major diseases are...
As central-place foragers, seabirds from colonies located close to multiple and/or productive marine habitats might experience increased foraging opportunities and enhanced resilience to food shortages. We tested whether this hypothesis might explain divergent trends in 3 populations of black-legged kittiwakes Rissa tridactyla, a surface-feeding piscivore, in the eastern Bering Sea....
Central place foragers, such as breeding seabirds, need to commute between their nests and foraging grounds, thus close proximity of the breeding colony to productive oceanographic features might be beneficial for seabird reproduction. We tested this hypothesis by investigating the at-sea foraging and breeding behavior of thick-billed murres (Uria lomvia)...
Clostridium perfringens is an anaerobic, gram-positive, rod-shaped, spore-forming bacterium that leads to a broad range of diseases in humans and animals [23, 27, 50]. Among seven C. perfringens types (type A-G), type F is known to be the most common bacteria that is responsible for causing human food-borne disease outbreaks...
Clostridium perfringens is a Gram-positive, anaerobic, spore-forming bacterium that can produce as many as 17 different toxins and are responsible to cause a wide array of gastrointestinal (GI) and histotoxic diseases in humans and animals. As individual strains produce a subset of these toxins, C. perfringens strains can be classified...
We hypothesized that changes in southeastern Bering Sea foraging conditions for black-legged kittiwakes (Rissa tridactyla)
have caused shifts in habitat use with direct implications for population trends. To test this, we compared at-sea
distribution, breeding performance, and nutritional stress of kittiwakes in three years (2008–2010) at two sites in the...
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no use of basin habitats given that this prey is only
obtained in the basin (Paredes et al. 2012
We hypothesized that changes in southeastern Bering Sea foraging conditions for black-legged kittiwakes (Rissa tridactyla)
have caused shifts in habitat use with direct implications for population trends. To test this, we compared at-sea
distribution, breeding performance, and nutritional stress of kittiwakes in three years (2008–2010) at two sites in the...
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-Legged Kittiwakes to Prolonged
Food-Shortages around Colonies on the Bering Sea Shelf
Paredes R, Orben
We hypothesized that changes in southeastern Bering Sea foraging conditions for black-legged kittiwakes (Rissa tridactyla)
have caused shifts in habitat use with direct implications for population trends. To test this, we compared at-sea
distribution, breeding performance, and nutritional stress of kittiwakes in three years (2008–2010) at two sites in the...
Clostridium perfringens is a pathogenic anaerobic bacterium able to produce more than 17 toxins, allowing C. perfringins to cause a wide variety of diseases in humans and animals. Beside toxins production, C. perfringens able to form a highly resistance spores can survive in the environments for years. These spores are...
Clostridium perfringens type A isolates produce the spore-specific enterotoxin, CPE, upon sporulation in the gastrointestinal tract of humans and animals. Spo0A is a response regulator representing the major transcription factor for sporulation initiation in C. perfringens. In Bacillus subtilis, a multicomponent phosphorelay involving five histidine kinases (KinA-KinE), the intermediate response...
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)
Acknowledgments
The Sarker Lab:
Dr. Mahfuzur Sarker
I-hsiu Huang
Dr. Deepa Raju
DanielParedes-Sabja
Nahid
About 48 million cases of Foodborne illnesses (FBIs) are estimated to occur every year in the US. These are diseases caused by contamination of foods with bacteria, viruses, protozoa, parasites and toxic chemicals. Clostridium difficile infections (CDIs) are an important health-care and community associated problem. Since C. difficile spores have...
Clostridium perfringens is the causative agent of gas gangrene and the 3rd most common cause of type A food borne disease in the United States. Critical to the pathogenicity of C. perfringens is the ability of this bacterium to produce highly resistant, metabolically dormant spores that can resume metabolic function...
Vibrio parahaemolyticus is a foodborne pathogen recognized as the leading cause of acute gastroenteritis associated with consumption of raw and undercooked seafood, particularly raw oysters, with major symptoms of nausea, vomiting, abdominal cramps and diarrhea. It is estimated that 45,000 cases of V. parahaemolyticus infection occur each year in the...
Clostridium perfringens type A isolates producing enterotoxin (CPE) are an
important cause of both food poisoning (FP) and non food borne gastrointestinal
diseases (NFBGID) in both humans and animals. C. perfringens type A food
poisoning is caused by isolates carrying the CPE encoding gene (cpe) on the
chromosome while the...
Clostridium perfringens type A isolates, an anaerobic enterotoxigenic spore forming bacterium, are the third leading cause of food-borne disease in the United States. Factors that contribute to the virulence of C. perfringens include the ability of the bacterium to form heat resistant spores and to produce an enterotoxin (CPE). Although...
This thesis synthesizes surficial structural data, a detailed analysis of an earthquake in 1944, and historical seismicity into a new model of crustal scale deformation in the eastern Precordillera in northwestern Argentina in the vicinity of San Juan. The eastern Precordillera was uplifted during previous thin-skinned deformation episodes, and is...
Understanding which factors motivate farmers to adopt certain practices is an important part of helping to solve many agri-environmental issues. This study uses 19 interviews with farmers along Oregon’s Willamette River, a statewide producer survey, and select interviews with organizations and agencies active in the farming community to examine the...
Vibrio parahaemolyticus is frequently isolated or detected from raw seafoods, especially shellfish. Also, Listeria monocytogenes, Salmonella spp. are pathogens that are frequently found in ready-to-eat (RTE) seafood, such as smoked fish and shellfish, seafood salad, cooked shrimp and crabmeat, and seafood consumed raw. Two studies to improve safety in RTE...
Small-scale fisheries around the world are increasingly facing pressures from a range of environmental, economic, and social sources. In order to sustain the societal benefits of small-scale fisheries, it is imperative to understand how fishing communities adapt to disturbances. Fishermen often catch multiple different species as an adaptation technique because...
Learning to recognize objects is a fundamental and essential step in human perception and understanding of the world. Accordingly, research of object discovery across diverse modalities plays a pivotal role in the context of computer vision. This field not only contributes significantly to enhancing our understanding of visual information but...
Predators are fundamentally important for regulating and driving prey population dynamics as well as structuring ecological communities. Over-exploitation of marine resources has caused dramatic depletions of predatory fish species and shifts in marine community composition, with attendant declines in productivity and diversity of marine ecosystems. Despite the important ramifications of...
This is a bibliography of doctoral dissertations and masters' theses in forestry and related topics issued during the period from July 1981 through June 1990. The colleges and universities included are all accredited by the Society of American Foresters. The actual listings were supplied by the individual institutions. Topics covered...
Ovarian steroidogenesis is heavily controlled by the formation and function of the theca cells. A condition known as polycystic ovarian disease in humans and cystic ovarian disease in cattle is due to abnormal steroidogenesis. Knowing more about theca cell formation and function can aid in gaining further knowledge about polycystic...
Juvenile walleye pollock (Theragra chalcogramma) are one of the primary prey items for bird and mammal predators in the Bering Sea and support a large commercial fishery. An understanding of the environmental factors that determine the horizontal and vertical distribution of juvenile pollock is needed to estimate the effects that...
Environmental DNA sequencing has revealed the expansive biodiversity of microorganisms
and clarified the relationship between host-associated microbial communities and host
phenotype. Shotgun metagenomic DNA sequencing is a relatively new and powerful
environmental sequencing approach that provides insight into community biodiversity and
function. But, the analysis of metagenomic sequences is complicated...
Comparative phylogeography offers a unique opportunity to understand the interplay between past environmental events and life-history traits on diversification of unrelated but co-distributed species. Here, we examined the effects of the quaternary climate fluctuations and palaeomarine currents and present-day marine currents on the extant patterns of genetic diversity in the...
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) program (Grant # U915985) to
ERO. Thanks to E. Bandou, B. Degen, C. Proisy (French
Guiana), Daniel
Marine protected areas (MPAs) are increasingly being used as a conservation tool for highly mobile marine vertebrates and the focus is typically on protecting breeding areas where individuals are aggregated seasonally. Yet movements during the non-breeding season can overlap with threats that may be equally as important to population dynamics....
Back pain is the leading cause of disability worldwide, entailing a significant socioeconomic impact. A primary source of back pain can be attributed to intervertebral disc (IVD) degeneration allowing nerve ingrowth, facet joint arthritis, disc bulging, and osteophyte formations that press on nearby nerve roots or the spinal cord. While...
The first goal of this master’s thesis was to investigate the linkage between a non-destructive testing method, surface resistivity, and premature concrete deterioration brought on by chloride ingress and or freeze-thaw cycling. The experimental method for this project consists of taking surface resistivity measurements of reinforced concrete slabs after they...
Around the globe, an array of alternative agrifood movements has emerged largely in response to the ecological and socio-economic threat caused by industrialized agricultural processes. From organic agriculture, to Slow Food, Locavore, and the Food Sovereignty movement, people around the world are reasserting their right to healthy and culturally appropriate...
The variety of natural disasters provide different sets of characteristics and properties with unique challenges. One significant difference between hazard types is prewarning lead time, the amount of time individuals have from a potential warning to the disaster occurring. Rapid onset disasters may not provide an official warning about a...
In response to genotoxic stress, ATR and ATM kinases phosphorylate H2A in fungi and H2AX in animals on a C-terminal serine.
The resulting modified histone, called γH2A, recruits chromatin-binding proteins that stabilize stalled replication forks or promote
DNA double-strand-break repair. To identify genomic loci that might be prone to replication...
From February to September of 2001, a significant body of qualitive data was collected to investigate barriers for Hispanic participation in Oregon's managed care Medicaid program. As a means to investigate this topic, comments were solicited from physicians, hospital administrators, social service agencies, and low-income Hispanics through semi-structured focus groups...
A major challenge to the study of the peopling of the Americas is that much of the Bering Land Bridge (Beringia), the geographic area that people migrating from Northeast Asia into North America would presumably have passed through, is now submerged due to sea-level rise since the last glacial maximum....
Recognizing human actions in videos is a long-standing problem in computer vision with a wide range of applications including video surveillance, content retrieval, and sports analysis. This thesis focuses on addressing efficiency and robustness of video classification in unconstrained real-world settings. The thesis work can be broadly divided into four...
Small molecule drugs have been instrumental in our fight against diseases, beginning when some of the earliest ancient cultures used plant remedies to treat illnesses. More recently, the skill of isolating and characterizing the active ingredients within bioactive plants and microbial extracts has led to the isolation and design of...
This thesis presents a discussion of the main materialistic theories proposed to explain the process of development among the indigenous population of Latin America. Four theoretical approaches are presented and discussed. The first one deals with the social group referred to as peasants. The second one explains the process of...
According to The Joint United Nations Programme on HIV and AIDS report of regional
statistics for HIV/AIDS from 2001-2008, Latin America has the third highest prevalence of HIV/AIDS
among children and adults in the world with about 2 million infected in 2008. Among all of these
countries, Mexico has the...
A large, damaging earthquake in 1944 on a blind thrust fault caused 60 cm of surface rupture on the subsidiary La Laja fault and additional unmeasured growth of an associated backlimb fold. Both the fold and fault are components of the La Laja Fault System (LLFS) located 25 km northeast...
This dissertation addresses the problem of video labeling at both the frame and pixel levels using deep learning. For pixel-level video labeling, we have studied two problems: i) Spatiotemporal video segmentation and ii) Boundary detection and boundary flow estimation. For the problem of spatiotemporal video segmentation, we have developed recurrent...
Biodiversity loss is of global concern, and is due in part to deforestation and high consumer demand for wood and wood products. The neotropical tree species Cedrela odorata (“Spanish cedar” or “cedro”) is economically valuable for its wood and faces threats of overexploitation. Due to strong similarities in wood features...
This dissertation addresses the problem of semantic labeling of image pixels. In the course of our work, we considered different types of semantic labels, including object classes (e.g., car, person), 3D depth values (in the range 0 to 80 meters), and affordance classes (e.g., walkable, sittable). Semantic pixel labeling is...
Foliar fungi – pathogens, endophytes, epiphytes – form taxonomically diverse communities that affect plant health and productivity. The composition of foliar fungal communities is variable at spatial scales both small (e.g., individual plants) and large (e.g., continents). However, few studies have focused on how environmental factors and host plant traits...
Acculturative stress can be associated with increased conflicts between Latino parents and adolescent youth, and have negative effects on Latino immigrant parents' psychosocial functioning and parenting practices. Yet, the potentially deleterious effects of acculturative stress on Latino immigrant parents' psychosocial functioning and parenting practices may be mitigated through positive acculturative...
A sample of 1,003 women, age 22 in 1983-84 and age 27 in 1988-89, were
selected from the National Longitudinal Survey of Youth. Personal, familial, and
geopolitical predictors of alcohol consumption were evaluated at each time period and
longitudinally. The study integrated macro- and micro-level influences to determine
their influence...
Since the 1930's, many fields on the Crooked River National grasslands have been seeded to crested wheatgrass (Agropyron desertorum). While some of these fields remain dominated by crested wheatgrass others had a greater presence of deep rooted native perennial grasses such as bluebunch wheatgrass (Pseudoroegneria spicata). Twenty eight fields previously...
Sugar phosphate cyclases (SPCs) are enzymes involved in the biosynthesis of many important natural products. SPCs form a unique cyclitol during the early steps in the biosynthesis of many natural products. These natural products include rifamycin, which is chemically modified to rifampicin and used clinically as an antituberculosis drug, and...
After decades of expert-based modernization efforts that have had profound negative impacts on human and environmental health, Ecuador is currently pursuing a rights-based, participatory development paradigm known as sumak kawsay or "the good life". Despite its promises of inclusion and interculturality, this approach continues to rely on highly trained specialists,...
Lambic and other barrel-aged beer styles are gaining popularity in the United States and Europe and are often treated as a premium product that can command a premium price. However, these styles can be prone to spoilage during the barrel-aging process, which represents a significant time and product commitment by...
Since the 1952 Bolivian agrarian reform, farmer unions have sought to establish themselves as producers for regional markets. Development strategies led by the World Bank and IMF have largely jeopardized small farmers, and challenged farmers to meet market demands. At present, a new agrarian revolution is being implemented and is...
My work on computing complex catalyzed organic transformations reveals that only a few subtle chemical factors, e.g. non-classical hydrogen bonding, (hyper)conjugation and steric effects, common across different catalyst manifolds are critical for catalysis and selectivity. Rational manipulation and exploitation of these factors has led to improved catalyst designs, which has...
Ph.D. candidate Qi Wei's thesis consists of two projects: Chemotherapy Project: a study based on the research paper "Predicting chemotherapy response of various cancer types using a variational auto-encoder approach" submitted to the bioRxiv preprint archive and accepted by the BMC bioinformatics; and Wound Monitor Project: implementing and assessing analytics...
This dissertation addresses few-shot object segmentation in images. The goal of segmentation is to label every image pixel with a class of the object occupying that pixel, where the class may represent a semantic object category or instance. In few-shot segmentation, training and test datasets have different classes. Every new...
In this dissertation, I examine the process of building a Sámi food movement in northern Sweden. Using 15 months of ethnographic research that included observation of food events (n=100) and semi-structured interviews with food producers and activists (n=47), I describe how Sámi individuals are incorporating global food activism frameworks into...
Xanthohumol, a prenylated flavonoid found in hops and beer, possesses a long-standing reputation to improve health. Xanthohumol’s cytotoxicity to a wide variety of cancer cell lines is well-established. Herein we provide further insight into the cytotoxicity of not only xanthohumol, but also its non-estrogenic derivatives, to a number of colonic...
Biodiversity loss in highly diverse systems such as coral reefs has been linked to significant declines in the ecosystem functions and services provided by marine species. Ecological functioning of coral reefs and the resistance of coral reef fish communities to disturbance depend on the functional traits of species that promotes...
The function of a protein is defined by its three-dimensional structure, and in understanding the three-dimensional structure of a protein, we gain an understanding of its function and mechanism. Protein structures, especially at high resolution, can provide detailed insights into many elements of enzyme function and catalysis – identifying residues...
Plant pathogenic Rhodococcus species are persistent pathogens able to cause severe growth deformities on a large range of hosts. The most well studied species, R. fascians is predicted by current models to synthesize a mixture of cytokinins that act to directly perturb the hosts' hormone balances, which results in abnormal...