A transient code (TFETC) for calculating the temperature
distribution throughout the radial and axial positions of a
thermionic fuel element (TFE) has been successfully developed.
It accommodates the variations of temperatures, thermal power,
electrical power, voltage, and current density throughout the
TFE as a function of time as well as...
The well-known fact that tropical sea level can be usefully simulated by linear wind driven models recommends it as a realistic test problem for data assimilation schemes. Here we report on an assimilation of monthly data for the period 1975-1992 from 34 tropical Pacific tide gauges into such a model...
Molecular DNA markers have become widely used in all areas of genetic
research. The objectives of this thesis were to develop polymorphic markers in sunflower
and utilize the markers for genetic and candidate gene analyses. Amplified fragment
length polymorphism (AFLP) markers were used to estimate genetic similarities and
assess the...
Programming parallel machines has been a difficult and unrewarding task. The short lifespan of parallel machines and their incompatibility have made it difficult to utilize them. Our goal here is to create an environment for parallel computing which allows users to take advantage of parallel computers without writing parallel programs....
With the strong shift toward network-centric cluster-computing workload management has become increasingly important in both industrial and academic environments. To fully harness the distributed computing resources of the 32 PC's in our department, I developed a workload monitoring system together with a few utilities for users to submit either sequential...
Test case prioritization techniques schedule test cases for regression testing in an order that increases their ability to meet some performance goal. One performance goal, rate of fault detection, measures how quickly faults are detected within the testing process. The APFD metric had been proposed for measuring the rate of...
Regression testing is an expensive testing process used to validate changes made to previously tested software. Different regression testing techniques can have different impacts on the cost-effectiveness of testing. This cost-effectiveness can also vary with different characteristics of test suites. One such characteristic, test suite granularity, reflects the way in...
How can rigorous forms of testing be supported in a way that is both compatible with the visual aspect of visual programming languages, and usable by the audiences using those languages - even when the audience has no background in software engineering? Visual programs are likely to contain at least...
Regression testing is an expensive software engineering activity intended to provide confidence that modifications to a software system have not introduced faults. Test case prioritization techniques help to reduce regression testing cost by ordering test cases in a way that better achieves testing objectives. In this thesis, we are interested...
In its simplest form, the process of diagnosis is a decision-making process in which the diagnostician performs a sequence of tests culminating in a diagnostic decision. For example, a physician might perform a series of simple measurements (body tem- perature, weight, etc.) and laboratory measurements (white blood count, CT scan,...
This thesis presents an automated methodology to calibrate the substrate profile for accurate prediction of substrate parasitics using Green's function based extractors. The technique requires fabrication of only a few test structures and results in an accurate three layered approximation of a heavily doped epitaxial silicon substrate. The obtained substrate...
Selenoprotein W (SeW) is a protein whose function is unknown, but potentially plays a vital role in calcium metabolism, as an indirect link has been established with white muscle disease (WMD). White muscle disease occurs in selenium deficient animals, and is characterized by the precipitation of calcium in muscle, leading...
Beet yellows virus (BYV) is a filamentous, positive-strand RNA virus that belongs to the family Closteroviridae. BYV particles encapsidate a 15.5 kb RNA and posses complex polar architecture. A long virion body is formed by the major capsid protein(CP), whereas the minor capsid protein (CPm) assembles a short tail that...
Wildtype sunflower typically produces 12-24% oleic acid (18:1) and 70-82%
linoleic acid (18:2). High-oleic sunflower, by contrast, produces up to 80-94% oleic
acid. The monounsaturated oleic acid has a greater oxidative stability than the
polyunsaturated linoleic acid, predominant in wildtype sunflower, and has greater
nutritional benefits than polyunsaturated and saturated...
Successful software systems evolve over their lifetimes through the cumulative changes made by software maintainers. As software evolves, the problems resulting from software change worsen, exacerbated by increased system size and complexity, lack of program understanding, amount of effort required to make changes, and number of personnel involved. Experience shows...
The purpose of this research is to investigate how stakeholders involved in collaborative watershed groups in Oregon work with each other to form ideas and take action. Most collaboration efforts include encouraging a high level of trust with a great value placed on relationships and partners, being open and flexible,...
A comprehensive tribal-level classification for the world's subfamilies of Hesperiidae, the skipper butterflies, is proposed for the first time. Phylogenetic relationships between tribes and subfamilies are inferred using DNA sequence data from three gene regions: 943 bp of cytochrome oxidase subunit I (COI) (in the mitochondrial genome), 739 bp of...
The Line Integral Convolution (LIC) is a mainstay of flow visualization. It is, however, computationally intensive, which limits its interactivity. Also, when used to view three-dimensional (3D) vector fields, the resulting images are dense and cluttered, making it difficult to perceive the flow on the interior parts of the field....
RNA silencing pathways are required for a wide variety of processes in most
eucaryotes. In plants, small-interfering RNA (siRNA) arising from transposons and other
repetitive sequences is associated with heterochromatin formation and maintenance.
MicroRNAs and trans-acting siRNAs encoded at discrete loci function as negative regulators of
gene expression by triggering...
PDMS membrane-based microvalves are becoming increasingly more important for the control of fluid flow within MECS applications such as microreactors used to synthesize nanoparticles and biological macromolecules. The motivation for pursuing PDMS membrane-based microvalves is for implementing a plug flow microreactor to simulate slug flow yielding a narrower residence time...
Solid state luminescent sulfides are prepared as powders in order to elucidate the relationship between structure and light emission. While the sulfides studied in this dissertation are known phosphors, materials are investigated in a variety of new ways. Elementary properties and structures of MgS are reviewed, and preparation of MgS...
________________________________________________________________________
Dean of the Graduate School
I understand that my dissertation will become part of the
Antineutrino detectors could provide a valuable addition to current safeguards
regimes. Antineutrinos are an attractive emission to monitor due to their low
interaction cross-section that prevents them from being shielded and the dependence
of their spectrum on the power level and isotopic content of a reactor core. While
there are...
_____________________________________________________________________
Dean of the Graduate School
I understand that my dissertation will become part of the
In this dissertation we study the electromagnetic properties of planar waveguides
with non-magnetic strongly anisotropic dielectric cores. We develop an analytical
description of the mode propagation in these systems and show that the index
of refraction can be either positive or negative depending on the specific material
parameters. Propagating modes...
7,7'-Dihydroxy-8,8'-biquinolyl (azaBINOL) was prepared from 7-hydroxyquinoline via N,N-dimethyl O-quinol-7-yl carbamate by directed ortho-metallation followed by FeCl₃-mediated oxidative coupling of the 8-lithioquinoline intermediate. Saponification of the resulting dicarbamate provided crystalline (±)-azaBINOL in 56% overall yield. 6,6'-Bis(dimethylaminocarbonyl)-7,7'-dihydroxy-8,8´-biquinolyl was prepared from the same dicarbamate by a double anionic-Fries rearrangement in 43% yield. 7,7'-Bis(diethylamino-carbonyloxy)-6,6'-diiodo-8,8´-biquinolyl...
Many D2d-symmetric 2,2',6,6'-tetrasubstituted biphenyls are
readily prepared via net oxidative dimerization of appropriate
1,3-disubstituted benzenes. Conversion of such proprochiral
compounds to useful C2-symmetric chiral biphenyls requires
formal replacement of two substituents on opposing aryl ring
units with alternate groups. This under exploited
desymmetrization tactic has been demonstrated for the
generation...
Papain-like leader proteases are found in diverse families of human, animal, plant, and fungal positive-strand RNA viruses. In addition to autocatalytic processing, these proteases play a variety of roles in the virus life cycle. In particular, the leader protease (L-Pro) of a prototype member of the Closterovirus genus, Beet yellows...
In previous work (Blakemore et al. Org. Lett. 2005, 7, 4721; Heterocycles 2006, 70, 609), successful elaborations of the lupine alkaloids (±)-α-isosparteine (dl-2) and (±)-β-isosparteine (dl-3) were realized from a common tetraoxobispidine precursor, 3,7-diallyl -2,4,6,8-tetraoxo-3,7-diazabicyclo[3.3.1]nonane (93). Herein, the tetraoxobispidine approach to lupine alkaloids was extended to a total synthesis of...
Real-time, high efficiency neutron spectroscopy has, historically, been a persistent challenge in the field of radiation detection and, for the most part, has gone unsolved. The most promising method to resolve this challenge, is the boron-capture technique using an organic scintillation system (BC-523a). Detectors that utilize this method possess an...
In order to address the energy needs of developing countries and remote communities, Oregon State University has proposed the Multi-Application Small Light Water Reactor (MASLWR) design. In order to achieve five years of operation without refueling, use of 8% enriched fuel is necessary.
This dissertation is focused on core design...
Detection technique that proposed utilizing electrochemically controlled, reversible ion extraction into polymeric membrane in an alternating galvanostatic/ potentiostatic mode was introduced. This method is studied in detail to comprehend the advantages of the novel sensor (pulstrode) compared to the potentiometric ion selective electrode (ISE), studies included possible applications and limitations....
A novel method for detecting the peptidase activity of clinically relevant peptidases was investigated using solid-contact electrochemical polyion sensors under chronopotentiometric control. Complete instrumental control over ion-extraction was accomplished by incorporating a lipophilic electrolyte into the ion-selective membrane; the sensors had no intrinsic ion-exchange capabilities. The sensors were used to...
The Department of Nuclear Engineering and Radiation Health Physics (NE/RHP) at Oregon State University (OSU) has been developing an innovative modular reactor plant concept since being initiated with a Department of Energy (DoE) grant in 1999.
This concept, the Multi-Application Small Light Water Reactor (MASLWR), is an integral pressurized water...
We have developed a compact micro total analysis system (μTAS) to serve as a platform for in-situ spectrophotometric water quality monitoring. Individual fluidic, optical, and electrical components were designed, developed, and characterized. These components were combined in both an integrated (single lithographic “chip-based” platform) and a modular manner. The microfluidic...
The development of micro total analysis systems (µTAS), also called “lab-on-a-chip”, or microfluidic analysis systems, is presented in this dissertation. Various research areas, covering subjects from magnetic particles synthesis to novel microchip fabrication techniques, are explored to develop a lab-on-a-chip system capable of performing magnetic bead-based bioassays. These devices are...
As the semiconductor industry works to integrate increasingly more "non-CMOS" devices onto CMOS ICs, compact model development has become an important step in the circuit/system verification tool flow. This research focuses on the two- and three-dimensional modeling of the physical phenomena that occur in nanoscale magnetic devices. This includes the...
Adjoint-derived weight windowing is a hybrid deterministic/Monte Carlo method to simulate radiation transport. In adjoint-derived weight windowing, a deterministic adjoint solution is used to create weight windows for a Monte Carlo simulation. The intent of this work is to identify factors that reduce the Figure of Merit (FOM) of Monte...
Transcriptomics and gene expression profiling enables the elucidation of the genetic response of an organism to various environmental cues. Transcriptomics enables the deciphering of differences between two closely related organisms to the same environment and in contrast, enables the elucidation of genetic responses of the same organism to different environmental...
Detection of reactor antineutrinos for non-proliferation applications has been researched extensively across the globe and is considered as a potential technology to remotely monitor reactor operations without any intrusions to reactor components. Reactor antineutrino detection experiments have been conducted in the past and have proven successful in detecting the changes...
Within the past several years the technology of high-throughput sequencing has transformed the study of biology by offering unprecedented access to life's fundamental building block, DNA. With this transformation's potential a host of brand-new challenges have emerged, many of which lend themselves to being solved through computational methods. From de...
Ion-selective polymeric optical sensors – ion optodes – are a promising alternative to ion-selective electrodes and fluorescent dyes for analytical and biological applications, e.g. extra- and intracellular measurements. They are non-toxic, highly selective robust probes for ionic fluxes monitoring.
A large-scale fabrication of ion optodes using a solvent displacement method...
The Multi-Application Small Light Water Reactor (MASLWR) is a small natural circulation pressurized light water reactor design that was developed by Oregon State University (OSU) and Idaho National Engineering and Environmental Laboratory (INEEL) under the Nuclear Energy Research Initiative (NERI) program to address the growing demand for energy and electricity....
Climate changes are growing environmental concerns which are much in the scientific government and public eye at present. The potential impact on aquatic resources and livelihood are immense. From local to global levels, fisheries and aquaculture play important roles for food supply, food security and income generation. Some 43.5 million...
NCRP report No.160 states that medical exposure increased to nearly half of the total radiation exposure of the U.S. population from all sources in 2006 (NCRP 2009). Part of this increase in exposure is due to the rise in nuclear medicine procedures. With this observed growth in medical radionuclide usage,...
Studies of light-matter interactions in organic semiconductors and in optical tweezer trapping of nanoparticles are presented. In the research related to organic semiconductor materials, a variety of novel materials and their composites have been characterized, and physical mechanisms behind their optoelectronic properties have been established. Three novel functionalized hexacene derivatives...
The improvement of the agricultural and wine-making qualities of the grapevine (Vitis vinifera) is hampered by adherence to traditional varieties, the recalcitrance of this plant to genetic modifications, and public resistance to genetically modified organism (GMO) technologies. To address these challenges, we developed an RNA virus-based vector for the introduction...
Understanding and modeling microbial responses and feedbacks to climate change is hampered by a lack of a framework in the pelagic environment by which to link local mechanism to large scale patterns. Where terrestrial ecology draws from landscape theory and practice to address issues of scale, the pelagic seascape concept...
In the 1970s and 1980s, there was considerable interest in near-equatorial variability at periods of days to weeks associated with oceanic equatorial inertia–gravity waves and mixed Rossby–gravity waves. At that time, the measurements available for studying these waves were much more limited than today: most of the available observations were...
DNA has a well-defined structural transition-the denaturation of its double-stranded form into two single strands-that strongly affects its thermal transport properties. We show that, according to a widely implemented model for DNA denaturation, one can engineer DNA 'heattronic' devices that have a rapidly increasing thermal conductance over a narrow temperature...
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A SNP resource for Douglas-fir: de novo transcriptome assembly and SNP detection and validation
Author(s): Howe, GT (Howe, Glenn T.)[ 1 ] ; Yu, JB (Yu, Jianbin)[ 1 ] ; Knaus, B (Knaus, Brian)[ 2 ] ; Cronn, R (Cronn, Richard)[ 2 ] ; Kolpak,...
The purpose of this thesis is to design a robust test facility for a small space nuclear power system and model its physical behavior under different scenarios. The test facility will be used to simulate a 1-10kWe nuclear reactor, its electrical generation, and heat removal capabilities. This simulator will be...
The elimination of soluble boron creates several advantages for Small Modular Reactor (SMR) operation. Most of these advantages are realized through significant core simplification (removal of pipes, pumping, and purification systems), the removal of the corrosive effects of soluble boron, and from improved safety effects. However, removing soluble boron creates...
Signs of climate change across the Pacific Northwest indicate changing patterns of timing and availability of stream flow. Declining summer low flows, decreasing snow pack, higher temperatures and an increasing fraction of mountain precipitation falling as rain, raise concerns about future reliability of stream flows. These changes will likely affect...
The recent 2013 Oregon State Board of Agriculture report identified several ways to improve agricultural income in Oregon. Recommendations to improve water development are at the top of the report's list of objectives. In this study, I analyze the relationship between net cash farm income (NCFI) and a cross-sectional set...
This study focuses on iodine-131 detected in milk samples from the Dairy Science Unit at Cal Poly, San Luis Obispo, California following events at the Fukushima Dai-ichi Nuclear Power Plant in March of 2011. The samples were collected as part of the Diablo Canyon Nuclear Power Plant (DCPP) Radiological Environmental...
Global electromagnetic (EM) induction studies have been the focus of increasing attention during the past few years. A primary stimulus for this interest has been increased quality, coverage and variety of the newly available data sets especially from recent low-Earth-orbiting satellite missions. The combination of traditional ground-based data with satellite-borne...
Small modular reactors (SMRs) are a recent advancement in commercial nuclear reactor design with growing interest worldwide. New SMR concepts, such as the Multi-Application Small Light Water Reactor (MASLWR), must undergo a licensing processes established by the U.S. Nuclear Regulatory Commission (NRC) prior to commercial operation. Given the lack of...
Pathogen invasions pose a growing threat to ecosystem stability and public health. Guidelines for the timing and spatial extent of control measures for pathogen invasions are currently limited, however. We conducted a field experiment using wheat (Triticum aestivum) stripe rust, caused by the wind-dispersed fungus Puccinia striiformis, to study the...
This project was a proof of concept of the use of the RAVEN software, a tool developed for the Risk Informed Safety Margin Characterization (RISMC) approach, with RELAP5-3D. This novel approach combines older probabilistic and mechanistic approaches to look at how and why the complex systems of a nuclear power...
Pseudoperonospora cubensis is an obligate pathogen and
causative agent of cucurbit downy mildew. To help advance
our understanding of the pathogenicity of P. cubensis, we
used RNA-Seq to improve the quality of its reference
genome sequence. We also characterized the RNA-Seq
dataset to inventory transcript isoforms and infer alternative
splicing...
The development and some applications of holographic optical tweezers (HOT) are presented. Our HOT system uses a spatial light modulator (SLM) to control the location and properties of the optical trap. We have developed a method for optimizing the diffraction efficiency of a SLM that can be applied in situ...
The Open Modeling Environment (OME) is a tool developed to address some known shortcomings in ecological System Dynamics (SD) modeling research. OME provides a common set of methods for interacting directly with spatial information, reducing the need for modelers to create their own methods for doing so. The environment is...
Here we present a phylogeny of beetles (Insecta: Coleoptera) based on DNA sequence data from eight nuclear genes, including six single-copy nuclear protein-coding genes, for 367 species representing 172 of 183 extant families. Our results refine existing knowledge of relationships among major groups of beetles. Strepsiptera was confirmed as sister...
This honors undergraduate thesis examines the process of simulating power system state estimation, the use of the alternating direction method of multipliers in the problem of distributed power system state estimation, and provides a rudimentary asynchronous implementation of the above for a linearized DC power system. The asynchronous implementation is...
European hazelnut (Corylus avellana L.) is an important crop Oregon's Willamette Valley, producing 99% of the hazelnuts grown in North America and brings over US $60 million dollars to the region annually. Hazelnuts are rich in fiber and vitamins, as well in demand by consumers due to their popularity as...
Time-dependent electronic transport is increasingly important to the state-of-the-art device design and fabrication. The development of nanoscale sensing, the harnessing and control of structural fluctuations, and the advancement of next-generation materials all require a treatment of quantum dynamics beyond the level of traditional methods and a more nuanced approach to...
Modeling tire-snow interaction is important in designing effective snow tires, which directly affects road safety during wintry weather. Unfortunately, tires have complex tread designs and the physical properties of snow have not been characterized. We employ the Material Point Method (MPM) for simulating a material that mimics the fracturing and...
At a time when the biodiversity on Earth is being rapidly lost, new technologies and methods in genomic analysis are fortunately allowing scientists to catalog and explore the diversity that remains more efficiently and precisely. The studies in this dissertation investigate genomic diversity within the milkweed genus, Asclepias, at multiple...
Recognizing human actions in videos is a long-standing problem in computer vision with a wide range of applications including video surveillance, content retrieval, and sports analysis. This thesis focuses on addressing efficiency and robustness of video classification in unconstrained real-world settings. The thesis work can be broadly divided into four...
Miniaturized and portable microfluidic analytical platforms have been widely explored in the broad field of chemical analysis. The concept of microfluidics offer a number of important advantages, including low reagent consumption, low-cost detection, high sample throughput, and shorter analysis time. Semiconductor nanocrystals or quantum dots have been extensively utilized in...
State-of-the-art personal robots need to perform complex manipulation tasks to be viable in complex scenarios. However, many of these robots, like the PR2, use manipulators with high degrees of freedom. High degrees of freedom are desirable from a functionality standpoint, but make the learning task more difficult by adding a...
This work is a culmination of a series of published works related to the use of the Material Point Method (MPM) in modeling wood adhesive bonds. The use of wood as construction material has the potential to play a small role in the solution to the current CO2 and climate...
This thesis addresses the problem of temporal action segmentation in videos, where the goal is to label every video frame with the appropriate action class present. We focus on the domain of NFL football videos, where action classes represent common football play types. For action segmentation, we use a temporal...
Geographical datasets are large, complex, and can be difficult for users to navigate and derive meaning from. These datasets, as well as the unique insights derived from them, provide tremendous opportunity for social change -- many of the global challenges humankind is currently facing can benefit from analytics or visualization...
During the eighteenth century, diagrams increasingly became an important aspect of scientific inquiry. Diagrams employed simplification as a strategy for representing complex information, played a role in standardizing scientific language, and served as instruments of reason to think through and communicate problems and findings in mathematics, physics, chemistry, astronomy, natural...
The dissertation focuses on the engineering of light-matter interaction using plasmonic nanoparticles and metamaterials to achieve enhanced luminescence and based on which to improve the performance of biosensing and light-emitting technologies. We designed and fabricated a spectrum of nanostructures to exhibit particular dispersion relations capable of controlling the spontaneous emission...
Microbial ecology has been transformed by metagenomics, the study of the genetic in-formation in entire communities of organisms. In the following we develop metagenomic tools arising from the classic Wasserstein metric as applied to questions regarding the diversity between microbial communities. We provide a novel proof of the characteriza-tion of...