Background/Objectives: Advanced glycation end products (AGEs) are implicated in the pathogenesis of atherosclerosis, diabetes and kidney disease. The objective was to describe dietary intake, the dominant source of exposure to AGEs, with carboxymethyl-lysine (CML), a major AGE, in serum and urine, respectively.
Subjects/Methods: Serum and urinary CML were measured in...
Pre-spawning mortality (PSM) presents a major problem for population recovery of spring Chinook salmon (Oncorhynchus tshawytscha) in the Willamette River basin. In certain reaches and years, PSM has exceeded 90%. Histology has been used as the primary diagnostic method to investigate PSM in the Chinook Salmon, and a collection of...
The purpose of this study was to determine if a 5-month
progressive-resistance exercise program would affect measures
of activities of daily living (ADLs) and functional stability
in elderly women. All subjects were ambulatory women, 80 to
93 years old, who lived in assisted-care facilities. Eight
exercise and 7 control subjects...
The purpose of this study was to determine if feeding dogs medium-chain triglycerides (MCT), fish oil, and L-carnitine enriched foods offsets age-associated changes in serum fatty acids (FA) and carnitine metabolites. Forty-one healthy Beagles, mean age 9.9 years (range 3.1 to 14.8), were fed control or one of two treatment...
Low physical activity levels and high serum C-reactive protein (CRP) levels are risk factors for coronary artery disease (CAD) in both men and women. However, postmenopausal women who take hormone replacement therapy (HRT) may have increased risk of CAD because of HRT-related increases in serum CRP. There are two manuscripts...
Health officials have recently been sounding the alarm that depression will soon
surpass many of the major medical conditions in causing disability among adults. Recent
demographic and health trends are generating public health concern about depression.
First, the prevalence of chronic conditions has dramatically increased over the last several
generations....
Case control studies of nonagenarians and centenarians provide evidence that long‐lived individuals do not
differ in the rate of disease associated variants compared to population controls. These results suggest that an enrichment
of novel protective variants, rather than a lack of disease associated variants, determine the genetic predisposition to
exceptionally...
Full Text:
, Andersen SL, Daw EW,
Terracciano A, FerrucciL and Perls TT. Genome‐wide association
study of
Purpose: We examined the prevalence and correlates of unmet assistance need with respect to activities of daily living (ADLs) and instrumental activities of daily living (IADLs) among older American Indians.
Design and Methods: Data for our analyses were collected in 2006–2008 as part of the Native Elder Care Study, a...
This study explores how a platform enables social media influencers to promulgate a consumption ideology. We show how gun influencers, or “gunfluencers,” use Instagram to link products, activities, and meanings to Second Amendment ideology—a gun-centric belief system in the United States colloquially known as “2A ideology.” Through a qualitative study...
The pursuit of personal goals has been linked to general psychological well-being, however, less is known about the association with depression in later adulthood when individuals are contending with age-related changes in health and social relationships. We explored the connection between both health and social relation goals (as measured by...
The relationship between the public and new technologies has historically been a tumultuous one, with public perceptions ranging from excited rapid adoption to standoffish pessimism. In 2011, IBM tried to use competition as a means of showcasing a new technology to the public. This thesis is a work of rhetorical...
As life expectancy continues to rise, adults over 65 are one of the fastest-growing age groups in the United States. As we have made significant strides in mitigating disease, we now have to consider health states that lead to disablement and the inability to age-in-place, including falls, frailty, functional mobility,...
BACKGROUND: The association of vitamin D with heart attack and stroke remains unclear.
METHOD: Using data from the Osteoporotic Fractures in Men Study (MrOS), we collected
dietary vitamin D data from 5,995 participants and serum (25)OH vitamin D from 1,606
participants. The association of vitamin D with prevalent heart attack...
INTRODUCTION: Between 2004 and 2010, the number of home births in the United States rose by 41%, increasing the need for accurate assessment of the safety of planned home birth. This study examines outcomes of planned home births in the United States between 2004 and 2009.
METHODS: We calculated descriptive...
Falls are extremely common among the older adult population, account for substantial morbidity and mortality, and are often potentially preventable. It is estimated that 9 out of 10 of hip fractures in older adults occur as the result of a fall. The economic consequences of hip fractures are estimated at...
INTRODUCTION: In 2004, the Midwives Alliance of North America's (MANA's) Division of Research developed a Web-based data collection system to gather information on the practices and outcomes associated with midwife-led births in the United States. This system, called the MANA Statistics Project (MANA Stats), grew out of a widely acknowledged...
Ample research has demonstrated the largely untapped potential of bioactive peptides (BAPs) for treating systematic chronic inflammation (SCI). Protein hydrolysates are the mixture of peptides resulting from the hydrolytic breakdown of a protein. Numerous hydrolysates contain BAPs and exert beneficial effects in both in vitro and in vivo models. In...
Epidemiological studies on Greenland Inuits in the 1970s and subsequent human studies have established an inverse relationship between the ingestion of omega-3 fatty acids [C₂₀₋₂₂ ω3 polyunsaturated fatty acids (PUFA)], blood levels of C₂₀₋₂₂ ω3 PUFA and mortality associated with cardiovascular disease [CVD]. C₂₀₋₂₂ ω3 PUFA have pleiotropic effects on...
Optimal aging is strongly related to personality factors along with health-behavior habits. Personality has played a key role in understanding the interactions between human behavior and the environment and as a vital predictor in determining health outcomes of individuals. Although previous studies have found links between personality traits and health,...