Background—The effect of intensive blood pressure (BP) lowering on kidney function among individuals with established cerebrovascular disease and preserved estimated glomerular filtration rate (eGFR) is not established.
Methods and Results—Among 2610 participants randomized to a lower (<130 mm Hg) versus higher (130–149 mm Hg) systolic BP target with repeated measures...
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Male Gender 1655 (63%) 570 (66%) 849 (64%) 236 (58%)
Race
Non-Hispanic
White
Background—The effect of intensive blood pressure (BP) lowering on kidney function among individuals with established cerebrovascular disease and preserved estimated glomerular filtration rate (eGFR) is not established.
Methods and Results—Among 2610 participants randomized to a lower (<130 mm Hg) versus higher (130–149 mm Hg) systolic BP target with repeated measures...
Full Text:
. McClure, PhD; Rebecca Scherzer, PhD;
Michelle C. Odden, PhD; CaroleL. White, PhD, RN; Michael Shlipak
Background—The effect of intensive blood pressure (BP) lowering on kidney function among individuals with established cerebrovascular disease and preserved estimated glomerular filtration rate (eGFR) is not established.
Methods and Results—Among 2610 participants randomized to a lower (<130 mm Hg) versus higher (130–149 mm Hg) systolic BP target with repeated measures...
Chemical compounds produced by organisms, or natural products, are excellent sources of inspiration for anticancer pharmaceutical discovery (Rodrigues et al., 2016). Microtubule targeting agents are a specific class of compounds, often discovered from natural sources, that have been developed as clinically successful anticancer therapies (Steinmetz and Prota, 2018). In the...
The death of a child is a traumatic family event. This qualitative study examined the experiences of parents and grandparents in 10 families who had lost a baby to SIDS, stillbirth, or birth defects. Key questions focused on support given and received, meanings attributed to the loss, continuing bonds, and...
This thesis is divided into three chapters. For all chapters, the experiments described deal with the responses of all or a subset
of 72 wind-pollinated Douglas-fir families from 36 different locations in southwestern Oregon. Wind-pollinated seed was collected from each of two trees at each of the 36 locations. The...
Published April 1993. Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalog
Oregon is a leader in production of premium wines in the United States and the industry has been expanding rapidly over the past few years. However, continued production and expansion of vineyards are threatened by infestation of phylloxera, Daktulospaira vitifoliae, an insect that feeds on roots. Most grapevines in Oregon...
Reproductive and endocrine disruption is commonly reported in aquatic species exposed to complex contaminant mixtures. We previously reported that Atlantic killifish (Fundulus heteroclitus) from the chronically contaminated Newark Bay, NJ, exhibit multiple endocrine disrupting effects, including inhibition of vitellogenesis (yolk protein synthesis) in females and false negative vitellogenin biomarker responses...
Since most wolf (Canis lupus) diet studies have been conducted in inland ecosystems, comparatively few data are available on diets of wolves in coastal systems. We investigated the diet of wolves in Glacier Bay, Alaska, from 12 May to 28 June in both 2010 and 2011. Although we identified 12...
The potent antitumor agent phorboxazole A was synthesized from six subunits comprising C1-C2 (115), C3-C8 (98), C9-C19 (74), C20-C32 (52), C33-C41 (84) and C42-C46 (85). Tetrahydropyrans B and C containing cis-2,6-disubstitution were fabricated via palladium(II)-mediated intramolecular alkoxycarbonylation which, in the case of tetrahydropyran C, was carried out with catalytic palladium(II)...
The island of Tahiti, the largest in French Polynesia, comprises two major volcanoes aligned NW-SE, parallel with the general trend of the Society Islands hotspot track. Rocks form this volcanic system are basalts transitional to tholeiites, alkali basalts, basanites, picrites, and evolved lavas. Through K-Ar radiometric dating we have established...
In June of 1994, the Oregon Agricultural Statistics Service (OASS) conducted a commodity survey that included an estimate of the number of equines (horses, ponies, mules, donkeys, miniatures, and zebras) in Oregon.
Recent warnings from scientists suggest there is limited time to enact policies to avert wide‐ranging ecological and social damage from climate change. In the United States, discussions about comprehensive national policies to avert climate change have begun, with “Green New Deal” proposals and climate plans put forth by members of...
The particle size distribution (PSD) is a critical aspect of the oceanic ecosystem. Local variability in the PSD can be indicative of shifts in microbial community structure and reveal patterns in cell growth and loss. The PSD also plays a central role in particle export by influencing settling speed. Satellite-based...
Tolerance of adult zebrafish and efficacy of emamectin benzoate and ivermectin in eliminating Pseudocapillaria tomentosa infection were evaluated. In the tolerance study, behavioral changes, fecundity, histopathology, and mortality were evaluated for in-feed administration of emamectin (0.05, 0.10, and 0.25 mg/kg) and ivermectin (0.05 and 0.10 mg/kg). All doses of emamectin...
We have measured the CO₂ concentration of air occluded during the last 40,000 years in the deep Siple Dome A (hereafter Siple Dome) ice core, Antarctica. The general trend of CO₂ concentration from Siple Dome ice follows the temperature inferred from the isotopic composition of the ice and is mostly...
Predator outbreaks are predicted to increasingly decimate economically and ecologically important prey populations because global climate change and food-web modifications frequently facilitate predators and stress prey. Natural systems are organized hierarchically, with processes operating at multiple scales giving rise to patterns of biodiversity, so predicting and managing outbreaks requires a...