This dissertation presents a research series demonstrating the use of pharmacokinetic modeling and simulations as tools to assess drug concentration and disposition in patient populations. For drugs requiring therapeutic drug monitoring, these tools are necessary to ensure patients are receiving a safe and effective dose of medication to address their...
Viral infections were investigated in American black bears (Ursus americanus) from Nevada and northern California with and without idiopathic encephalitis. Metagenomics analyses of tissue pools revealed novel viruses in the genera Circoviridae, Parvoviridae, Anelloviridae, Polyomaviridae, and Papillomaviridae. The circovirus and parvovirus were of particular interest due to their potential importance...
Fiber-optic-coupled dosimeters (FOCDs) are a relatively new method in which to obtain in-vivo dose concomitant with radiation treatment. Accurate live dosing can be achieved virtually anywhere due to their small dimensions (0.2 mm) which can be accommodated by a catheter. The purpose of this experiment is to characterize the electron...
How do you test a program when only a single user, with no expertise in software testing, is able to determine if the
program is performing correctly? Such programs are common today in the form of machine-learned classifiers. We consider the
problem of testing this common kind of machine-generated program...
Teacher efficacy continues to be an important area of study in educational research. This study tested an instrument designed to assess the perceived efficacy of agricultural education teachers when engaged in lessons involving mathematics instruction. The study population of Oregon and Washington agricultural educators utilized in the validation of the...
Taiwan separated from China as the result of the 1949 political upheaval between Chiang Kai-Shek's Nationalist Government and Mao Tse-Tung's Communists Party which concluded
with the Chinese Communist take over of mainland China and the establishment of the People's Republic of China. Since then, Taiwan, ROC and the PRC have...
Enabled by a rich ecosystem of Machine Learning (ML) libraries, programming using learned models, i.e., Software-2.0, has gained substantial adoption. However, we do not know what challenges developers encounter when they use ML libraries. With this knowledge gap, researchers miss opportunities to contribute to new research directions, tool builders do...
Empirical studies have shown that programmers spend up to one-third of their time navigating through code during debugging. Although researchers have conducted empirical studies to understand programmers’ navigation difficulties and developed tools to address those difficulties, the resulting findings tend to be loosely connected to each other. To address this...
Energy consumption has become a significant concern for cloud service providers due to financial as well as environmental factors. As a result, cloud service providers are seeking innovative ways that allow them to reduce the amount of energy that their data centers consume. They are calling for the development of...
Developers frequently change the type of a program element and update all its references for performance, security, concurrency, library migration, or better maintainability. Despite type changes being a common program transformation, it is the least automated and the least studied. Manually performing type changes is tedious since the programmers have...
Wave breaking in the surf zone is an important forcing
mechanism on the generation of nearshore currents and in the driving
of sediment transport. At the same time, wave breaking can have
significant spatial and temporal variability that needs to be
accounted for in the description of nearshore processes. Remote...
This paper discusses the merits of providing users variational views when editing variational code. I provide a plugin for the popular Atom Integrated Development Environment (IDE) which replaces #ifdef annotations commonly used by the C PreProcessor (CPP) with colored backgrounds, thus reducing code clutter and attempting to help programmers quickly...
Complex information environments are often organized as hierarchies. However, computational models of Information Foraging Theory (IFT) have almost entirely ignored this fact. Models and tools for predicting programmer navigations have ignored people’s foraging behavior across hierarchies —called hierarchical foraging. Without modeling hierarchical foraging, our ability to build tools to support...
This thesis explores the differences in puppetted and teleoperation control of robotic hands, using the Asterisk test as a benchmark. Two hands were tested, including modified versions of the Model Q and Model Q developed by Yale's GRAB Lab. Small differences were observed between the puppetted and teleoperation control of...
How can software practitioners assess whether their software supports diverse users? Although there are empirical processes that can be used to find “inclusivity bugs” piecemeal, what is often needed is a systematic inspection method to assess software’s support for diverse populations. To help fill this gap, this thesis introduces InclusiveMag,...
This algorithm presents the first steps towards a solution for novice database administrators that helps them transform a non-normalized relational database into a database in the third normal form. The algorithm uses relational algebra operations that apply principles from the third normal form. This provides the database administrator with an...
The deployment of advanced technology standards for 5G and beyond in cellular networks has resulted in interest in integrated circuits (ICs) operating at frequencies above 10GHz. This has sparked research on wideband circuits in commercial low-cost silicon technologies, operating at high RF and mm-wave frequencies. Given the wide range of...
This work details the development of 3D printed TPU pneunet actuators for use in apple picking for agricultural soft robotics. These actuators increase the force capabilities of soft pneunets and simplify manufacturing. Grippers based on these actuators are ideal for apple picking because they are compliant, yet exert sufficient force...
The range of verification problems that can be solved with logic model checking tools has increased significantly in the last few decades. This increase in capability is based on algorithmic advances and new theoretical insights, but it has also benefitted from the steady increase in processing speeds and main memory...
Surface Canopy Water (SCW) is the intercepted rain water that resides within the tree canopy and plays a significant role in the hydrological cycle. Challenges arise in measuring SCW in remote areas using traditional ground based techniques. Remote sensing in the radio spectrum has the potential to overcome the challenges...
One of the least studied areas of Information Foraging Theory
is diet: the information foragers choose to seek. For
example, do foragers choose solely based on cost, or do
they stubbornly pursue certain diets regardless of cost? Do
their debugging strategies vary with their diets? To investigate
"what" and "how"...
Magnetic materials can be used in modern soft robotics as a method for external stimulus actuation and motion control. By combining aspects of biology and mechanics, devices are fabricated to create a structure capable of complex movement. Applications that these devices are subject to can be broken down into four...
The Central American Free Trade Agreement (CAFTA) is between the United States and Costa Rica, Nicaragua, Honduras, Guatemala, El Salvador and the Dominican Republic. CAFTA was decided in Costa Rica by a national referendum in 2007, after years of delay that left Costa Rica as the only country to have...
A long-standing approach to deal with complex product development is to divide the system into smaller parts
and assign responsibility for developing those parts to particular teams. Conventional wisdom suggests that by
doing so, we reduce the communication overhead in the development project by making the separate
development teams as...
Did regulations restricting the harvest of cockle clams by recreational clammers also restrict commercial harvesting for crab bait? In the case of Netarts Bay, they did not. The reasons for the exemption are given in this document.
Broadband simulated dolphin echolocation signals were used to measure the ex situ backscatter properties of mesopelagic boundary community MBC in order to gain a better understanding of the echolocation process of spinner dolphins foraging on the MBC. Subjects were captured by trawling with a 2-m-opening Isaacs-Kidd Midwater Trawl. Backscatter measurements...
Wearable electronic devices are becoming increasingly widespread and are being used to fulfill a variety of needs. These devices range from purely infotainment type systems such as smartwatches and fitness oriented devices to specialized medical devices such as insulin pumps and heart-rate monitors. A challenge faced with all of these...
This report concerns the disposal of dredging spoil in the Rogue River estuary in 1948. Since there were few shellfish resources existing in the estuary at the time, Oregon Fish Commission biologists had no objection to make to the disposal of the dredged materials.
The microwave backscatter properties of surf zone waves are analyzed using field observations.
By utilizing a preexisting, independent, water surface discrimination technique, the microwave returns were
extracted along individual waveforms and the data from shoaling (steepening) waves, surf zone breaking
waves, and remnant foam were separated and quantified. In addition,...
Known as the fourth industrial revolution, digitization is an ongoing trend in all fields, in which various industries are integrating information technologies to support and improve their businesses. Nuclear technology industries have also increased their interest in data-driven methods by leveraging the potential of pattern recognition to identify anomalies and...
Technological advancements, ever-evolving necessary skillsets, and an aging workforce have all contributed to a growing labor crisis wherein there are not enough qualified candidates available to fill vacant jobs in the manufacturing sector – in essence, a skilled labor shortage. Certificate programs (earned independently in a two-year college, while working...
The ability to create reproducible cryptographically secure keys from temporal environments (e.g., images) has the potential to be a contributor to effective cryptographic mechanisms. Due to the noisy nature of these environments, achieving this goal in a user friendly fashion is a very challenging task, especially since there exists a...
Generating abundant, renewable energy from Earth’s oceans is an attractive option for meeting increasing energy demand. Marine renewable energy also comes with the variability of renewable sources, which impact the reliability and power quality of the electrical grid. On a transmission-level, this dissertation looks at ensuring reliability of the power...
The ubiquity of high quality video and proliferation of mobile devices has contributed to an unprecedented rise in video consumption. HTTP, in conjunction with adaptive streaming, has become the de facto mechanism for delivering the vast majority of video as it readily caters to heterogeneous networks and devices. This dissertation...
Users curate music playlists based on emotion to focus or relax, so streaming services often create playlists of songs to aid this process. Prior research focuses on generating playlists of a single mood or genre, although a few studies work to construct automatic playlists that transition between the genres of...
Low-level nuclear power plant outages in the United States can lead to unanticipated costs, potentially compromising the expected operation lifetime of the plant. Nuclear power plants are complex systems of interfacing components and highly regulated processes. This inherent complexity makes predicting outages from system dependencies very challenging. When outages do...
The term "Intuitive use" has become a common phrase to describe interfaces and products, however it is rarely defined. Research regarding intuitive use is in its infancy, beginning primarily in 2003. With the development of new terms in Human Factors and Human-Computer Interaction, it is important for Designers and Users...
Soil moisture is an essential climate variable influencing land–atmosphere interactions, an essential hydrologic variable impacting rainfall–runoff processes, an essential ecological variable regulating net ecosystem exchange, and an essential agricultural variable constraining food security. Large-scale soil moisture monitoring has advanced in recent years, creating opportunities to transform scientific understanding of soil...
Theories of human behavior are an important but largely untapped resource for software engineering research. They facilitate understanding of human developers’ needs and activities, and thus can serve as a valuable resource to researchers designing software engineering tools. Furthermore, theories abstract beyond specific methods and tools to fundamental principles that...
Increasing threats of terrorism and contraband smuggling have led to a growing interest in millimeter wave/ THz security sensors. Recently, systems combining active and passive sensing into one unit have been proposed where the active mode provides information on range and reflectivity, and the passive mode complements the active by...
The target strength as a function of aspect angle were measured for four species of fish using dolphin-like and porpoise-like echolocation signals. The polar diagram of target strength values measured from an energy flux density perspective showed considerably less fluctuation with azimuth than would a pure tone pulse. Using detection...
Ornithology is an exciting field with novel research emerging everyday. Researchers in bioacoustics often spend hours within the wilderness recording bird calls to analyze later in their lab. The burden of sifting through hours of audio recordings from the field continues to remain a time-consuming and manual task, despite the...
The design of programming tools is slow and costly. To ease this process, we have developed a design pattern catalog aimed at providing guidance about how to design tools for developers. This guidance is grounded in Information Foraging Theory (IFT), which empirical studies have shown to be useful for understanding...
Thermoelectric generators (TEGs) have gained much popularity in the search for alternatives to clean sources to harvest energy. Given their capability to harness an electric potential given a temperature differential across their opposing faces, and the foreseeable prevalence of naturally and/or commonly occurring temperature gradients in multiple applications, TEGs are...
Visualizing large movement datasets with flow maps is difficult because overlapping flows create significant graphical conflicts that make accurate interpretation difficult or impossible. Interactive flow mapping applications allow users to explore large movement datasets by automatically generating flow maps from subsets of the data in response to queries by the...
Predicting the average affect of a piece of music is a task which has been of recent interest in the field of music information retrieval. We investigate the use of sentiment analysis on online social media conversations to predict a song’s valence and arousal. Using four music emotion datasets -...