Transfer students often experience difficulties in
adjusting to a new institutional environment, and these
difficulties may limit their academic potential. Success
predictors identified in research may not be part of their
experiences. Can an institution create a formal process
which can ameliorate deficiencies within success factors
for transfer students? This...
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants generated as byproducts of natural and anthropogenic combustion processes. Despite significant public health concern, physiologically based pharmacokinetic (PBPK) modeling efforts for PAHs have so far been limited to naphthalene, plus simpler PK models for pyrene, nitropyrene, and benzo[a]pyrene (B[a]P). The dearth of...
Dibenzo[def,p]chrysene (DBC) is a transplacental carcinogen in mice (15 mg/kg; gestation day (GD) 17). To mimic residual exposure throughout pregnancy, dams received 4 smaller doses of DBC (3.75 mg/kg) on GD 5, 9, 13 and 17. This regimen alleviated the previously established carcinogenic responses in the thymus, lung, and liver....
Dibenzo(def,p)chrysene (DBC), (also known as dibenzo[a,l]pyrene), is a high molecular weight polycyclic aromatic hydrocarbon (PAH) found in the environment, including food, produced by the incomplete combustion of hydrocarbons. DBC, classified by IARC as a 2A probable human carcinogen, has a relative potency factor (RPF) in animal cancer models 30-fold higher...
Dibenzo(def,p)chrysene (DBC), (also known as dibenzo[a,l]pyrene), is a high molecular weight
polycyclic aromatic hydrocarbon (PAH) found in the environment, including food, produced by
the incomplete combustion of hydrocarbons. DBC, classified by IARC as a 2A probable human
carcinogen, has a relative potency factor (RPF) in animal cancer models 30-fold higher...
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Human in vivo Pharmacokinetics of [¹⁴C]Dibenzo[def,p
Dibenzo(def,p)chrysene (DBC), (also known as dibenzo[a,l]pyrene), is a high molecular weight
polycyclic aromatic hydrocarbon (PAH) found in the environment, including food, produced by
the incomplete combustion of hydrocarbons. DBC, classified by IARC as a 2A probable human
carcinogen, has a relative potency factor (RPF) in animal cancer models 30-fold higher...
Full Text:
Corley, R. A.
(2013) Impact of pregnancy on the pharmacokinetics of dibenzo-
[def,p]chrysene in mice
There are over two million pet rabbits in the United States. Many rabbits are obtained as adults from pet stores and humane societies. Pet rabbit owners may elect to perform ovariohysterectomy (spay) surgeries on female rabbits to prevent unwanted pregnancies as well as to eliminate the possibility of reproductive disorders...
Driven by major scientific advances in analytical methods, biomonitoring, computation, and a newly articulated vision for a greater impact in public health, the field of exposure science is undergoing a rapid transition from a field of observation to a field of prediction. Deployment of an organizational and predictive framework for...
Dibenzo[def,p]chrysene (DBC) is a highly potent, but less prevalent, environmental carcinogen belonging to a class of compounds known as Polycyclic Aromatic Hydrocarbons (PAHs). They are highly ubiquitous and arise as a byproduct of natural and anthropogenic combustion processes. Previous studies have documented carcinogenic effects upon in utero exposure of PAHs....
The objective of this work is to add to the body of translational data between high dose animal model research and the environmentally relevant human metabolism of the persistent pollutant dibenzo[def,p]chrysene (DBC). We furthered the knowledge of gene/exposure interactions by determining the carcinogenesis risk based on Cyp1b1 genotype following in...
Software engineers often need help with discovering and learning how to use APIs. For example, software engineers who are starting to learn Java, and they want to implement a certain feature in a program, they might want to reuse existing APIs in order to save time versus rewriting it themselves...
This project was designed to test the biological effects of three
levels of dietary protein (12.7, 16.3 and 19.3% CP on a dry matter
basis) on high producing Holstein-Friesian dairy cows. Forty five
second lactation or older cows that showed the potential to produce
over 31.75 kg (70 lbs) per...
Although science is widely accepted as a fundamental source of information underlying decisions about forest management and conservation, considerably less attention has been paid to the inevitable role that normative values and beliefs play in such decisions. This thesis highlights the normative dimensions of "ecological forestry," a strategy of forest...
The polycyclic aromatic hydrocarbon (PAH), benzo[a]pyrene (BaP), was compared to dibenzo[def,p]chrysene (DBC) and combinations of three environmental PAH mixtures (coal tar, diesel particulate and cigarette smoke condensate) using a two stage, FVB/N mouse skin tumor model. DBC (4 nmol) was most potent, reaching 100% tumor incidence with a shorter latency...
The seasonal concentration, turnover and mode of accumulation
of ³²P by the juvenile starry flounder in Alder Slough, a small eco-system in the Columbia River Estuary, was examined during 1969 and
1970.
Levels of ³²P and concentrations of total P were measured to
permit computation of specific activities (nCi³²P/g total...
Background: The numbers of Southeast Asian women in higher education, whether within administration, teaching faculty, or counseling and student services are scarce. The specific needs of minority women go largely unnoticed and remain unaddressed and may contribute to the low numbers of minority women in higher education leadership.
Purpose: The...
An evaluation was made on the nutritive value of tropical forages
and by-product feeds for rabbit production. Digestibility of nutrient
fractions, feed preferences, growth, combination of forages, supplementation
of micro and macro nutrients and/or effects of drying temperature
on the quality of four groups of forages, namely woody legumes
(WL),...
This thesis describes the development of a new enantioselective synthetic method employing chiral cis-2,5-diaminobicyclo[2.2.2]octane-based organometallic catalysts. The significance of this new method to organic synthesis is illustrated with preparation of enantioenriched products that are transformed to important pharmaceutical agents. Chapter 1 provides a brief historical overview of asymmetric catalysis, especially...
Recent mandates in the United States require federal agencies to incorporate climate change science into land management planning efforts. These mandates target possible adaptation and mitigation strategies. However, the degree to which climate change is actively being considered in agency planning and management decisions is largely unknown. We explored the...
The Diels-Alder reaction represents a promising tool for use in
asymmetric synthesis. The reaction involves a rigid transition state
that facilitates the formation of one diastereomeric transition state
and is reversible. This satisfies two necessary criteria for
asymmetric synthesis.
The Diels-Alder reactions of 1,l-dialkylspiro[2.4]-4,6- heptadienes
with maleic anhydride and p-benzoquinone...
To evaluate the immunologic and metabolic effects of OmniGen-AF® (Phibro Animal Health corporation, Quincy, IL; OG) supplementation in growing beef cattle, we designed three studies using replacement beef heifers (8.5 and 10.5 months of age) and steers supplemented across backgrounding, transition, and finishing periods. In Study 1, the effect of...
Two experiments involving 33 Holstein cows were conducted
for the primary purpose of studying the effects of flumethasone (a
synthetic glucocorticoid) on milk and milk constituent yields. The
secondary purpose was to compare udder health, reproductive performance,
and body weight changes of cows on flumethasone therapy.
Nine Holstein cows were...
Three experiments evaluated the effects of different management strategies on immune function and performance of feeder cattle. The objective of experiment 1 was to compare the effects of anticipating, delaying, or vaccinating against Bovine Respiratory Disease (BRD) at the time of weaning and feedlot entry on growth, DMI, and plasma...
Serum samples were collected between 24 and 48 h of age
from 408 Hereford calves of a selection experiment and from 200
Angus, Hereford and Red Poll calves of another experimental
population (Germ Plasm Utilization project). Concentrations of
Immunoglobulin G₁ (IgG₁) were determined by single radial
immunodiffusion. Breed or selection...
Background: Having conquered water surfaces worldwide, the semi-aquatic bugs occupy ponds, streams, lakes, mangroves, and even open oceans. The diversity of this group has inspired a range of scientific studies from ecology and evolution to developmental genetics and hydrodynamics of fluid locomotion. However, the lack of a representative water strider...
Lactate is an end-product of both aerobic and anaerobic glycolysis and it can be used as an energy source for tissues. It is produced by all cells in the mammalian body that can metabolize glucose. Increased production of lactate can be seen with there is an increase in cellular metabolism...
Evaluations of body form and measures of milk production were
recorded for 188 Holstein lactations and 77 Jersey lactations in the
Oregon State University Dairy Herds. Components of body form
included general appearance, dairy character, body capacity, and
mammary system and 34 sub-components of these four traits plus body
weight...
The production level of dairy cows fed corn cannery waste
silage was investigated during a 305 day lactation study. Eighteen
Holstein cows were paired according to their probable producing
ability and field corn silage was fed to the control pairmates, Forage
analyses (DM, CP, CF, and nitrates) were determined on...
This study examined relations between children’s attention span-persistence in preschool and later school achievement and college completion. Children were drawn from the Colorado Adoption Project using adopted and non-adopted children (N = 430). Results of structural equation modeling indicated that children’s age 4 attention span-persistence significantly predicted math and reading...
This qualitative study examines the experiences of Asian American students at a predominantly White institution in the cultivation of their racial identity development with the support of resources and services on campus, specifically an Asian cultural center. Six participants at a large, public research institution in the Northwest region were...
The extent to which responses to stress are maladaptive or adaptive to the long-term survival of fish remains to be better understood. The aim of this study was to identify differentially expressed genes in the livers of rainbow trout, Oncorhynchus mykiss, responding to an experimental stressor. Gene expression responses were...
FVB/N mice wild-type, heterozygous or null for Cyp 1b1 were used in a two-stage skin tumor study comparing PAH, benzo[a]pyrene (BaP), dibenzo[def,p]chrysene (DBC), and coal tar extract (CTE, SRM 1597a). Following 20 weeks of promotion with TPA the Cyp 1b1 null mice, initiated with DBC, exhibited reductions in incidence, multiplicity,...
Four experiments were conducted (1961-1964) for the primary
purpose of studying the milk and milk constituent yields of dairy cows
under dry lot and pasture systems of management. The secondary
purpose was to compare the health and breeding performance of cows
under these two systems.
Ninety-eight cows of the Holstein...
Job satisfaction has received considerable attention within the community college sector, but there is limited research focused solely on the job satisfaction of foreign-born faculty members employed at community colleges. The purpose of this study was to examine factors associated with job satisfaction among foreign-born faculty members employed at U.S....
Pre-spawning mortality (PSM) presents a major problem for population recovery of spring Chinook salmon (Oncorhynchus tshawytscha) in the Willamette River basin. In certain reaches and years, PSM has exceeded 90%. Histology has been used as the primary diagnostic method to investigate PSM in the Chinook Salmon, and a collection of...
An experiment was conducted to determine the effect a newborn calf would have on initial success rate, lactation performance, infertility and progesterone levels during mammogenesis and lactogenesis in dairy cows undergoing hormonal inducement to lactate. Fourteen Holstein, Brown Swiss and Jersey infertile, non-lactating cows, loaned by Pacific Northwest dairymen, were...
Three sets of blood samples were taken from 532 beef calves of two populations at 24 to 48 h after birth, at an average age of 164 d (at time of vaccination for infectious bovine rhinotracheitis virus or IBRV) and at an average age of 224 d (60 d postvaccination)....
The goals of this research were to a) characterize the protein-function relationships of skeletal muscle single fibers from the mouse hindlimb b) examine mouse-strain related differences in myosin heavy chain composition (MHC) and single fiber contractile function, and c) quantify changes in fiber size and contractile function in response to...
This study examined features of deep pool (>0.8 m mean depth) used by
adult summer steelhead in Steamboat Creek (1991-1992). Steamboat Creek had
a heterogenous thermal profile, with some segments exceeding preferred
temperature of steelhead. Deep pools were scarce (4% of the total habitat units)
and 39% of them were...
Acute lymphoblastic leukemia (ALL) encompasses a spectrum of lymphoid progenitors that have undergone malignant transformation and clonal proliferation at various stages of differentiation. Some cases of ALL have been documented to have prenatal origins and in particular neonatal exposure to various environmental pollutants is associated with increased disease risk, including...
Alkaline phosphatase (ALP) is an enzyme present in intestinal mucosa, bile, bone and renal tubule cells. Bile acids have been shown to decrease ALP activity from bone and kidney but not those from intestinal origin. This action can be mimicked in serum and peritoneal fluid samples by the use of...
The recent push to develop unconventional sources of oil and gas both in the U.S. and abroad via hydraulic fracturing (“fracking”) has generated a great deal of controversy. Effectively engaging stakeholders and setting appropriate policies requires insights into current public perceptions of this issue. Using a nationally representative U.S. sample...
The Willamette River has gone through extensive changes since Euro American settlement – changes that have reduced channel connectivity, destroyed important habitat for species and vastly undermined floodwater storage capacity. Efforts to preserve portions of the river have a controversial legacy that has left lingering suspicions of government involvement in...
Many carbon nanotube (CNT) applications require precisely controlled chemical
functionalization that is minimally disruptive to electrical performance. A promising approach is
the generation of sp³ hybridized carbon atoms in the sp²-bonded lattice. We have investigated the
possibility of using a carboxylic acid functionalized diazonium reagent to introduce a defined
number...
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. M.; Lyuksyutov, S.; Itkis, M. E.; Hamon, M. A.; Hu, H.; Cohn, R. W.;
Eklund, P. C.; Colbert, D. T
Establishing a therapeutic alliance or a therapeutic bond has long been seen as an essential component of obtaining positive treatment outcomes in clinical practice. More recently, the idea of recognizing therapeutic alliance ruptures (disagreements about the tasks or goals of therapy or a problem in the therapeutic bond) during counseling...