Osteoporosis is a skeletal disease affecting 44 million Americans. A primary strategy to prevent osteoporosis is to develop a high peak bone mass in youth. Oral Contraceptives (OCs) alter hormones in women and could affect bone mass development. The interaction between OCs and skeletal mineralization is poorly understood. PURPOSE: Our...
Exercise-related menstrual dysfunction (ExMD) is associated with low energy availability (EA), decreased bone mineral density (BMD), and increased risk of musculoskeletal injury. We investigated whether a 6-month carbohydrate-protein (CHO-PRO) supplement (360 kcal/day, 54 g CHO/day, 20 g PRO/day) intervention would improve energy status and musculoskeletal health and restore menses in...
Purpose of the Study
The purpose of this study was to investigate the
effects of a 12-month physical activity (jogging) program
on the bone density of cardiac-prone participants in the
Adult Fitness Program at the University of Wisconsin-
La-Crosse.
The following null hypotheses were tested:
1. There was no significant...
As a gymnast tumbles, she runs, pounces, flips and lands with a perfect thud. Some people cringe as they imagine the sequence to be painful, but science has recently shown the pounding may actually be beneficial. Many studies have found weight-‐bearing exercise encourages bone repair and calcification. Additionally, those who...
In order to develop a stimulating yet effective school-based program which elicits
a positive bone growth response, we need to understand the forces acting on the bones of
children during various high-impact activities. One activity found to promote bone
growth is drop landings from a height. We determined whether there...
Particles generated from wear of prosthesis joint bearing surfaces induce inflammation and promote pathological periprosthetic osteoclast-mediated bone resorption (osteolysis). Obesity increases the risk of prosthesis failure. However, despite being morbidly obese, leptin-deficient ob/ob mice are resistant to osteolysis. These findings suggest that leptin exerts effects that act to increase particle-induced...