BACKGROUND: Consumption of raspberry products have been observed to produce healthful effects and reduce weight gain and positively shift metabolism in mice fed obesigenic diets. In the past, our lab has successfully shown a reduction in weight gain for mice consuming RPC+HF vs. mice fed HF alone. Currently, there is...
Developing accurate predictive distribution models requires adequately representing relevant spatial and temporal scales, as these scales are ultimately reflective of the relationships between distributions and influential environmental conditions. In this research, we considered both spatial and temporal scale and the influence each has on predicting broad-scale distributions of two disparate...
Throughout most of the developed world, surgical sterilization via gonadectomy has become a common tool for combating the overpopulation of unwanted dogs as well as to eliminate the risk of reproductive diseases in pet dogs. In the dog as in other normal adult mammal, the hypothalamus secretes gonadotropin-releasing hormone (GnRH),...
Mitigating for increased human impact to the seafloor associated with resource extraction activities and renewable energy development can benefit from an understanding of the distribution of sensitive marine benthic species. Habitat suitability predictive modeling is a cost effective statistical tool to infer species distribution patterns from constrained sampling locations. However,...
Background
Bcl11b, previously CTIP2, is a zinc finger nuclear transcription factor involved in the development of keratinocytes, teeth, T lymphocytes, and nervous tissue. Expression of Bcl11b has been reported in human head and neck squamous cell carcinoma (HNSCC) and increased expression correlates with poorly differentiated tumors. This study aimed to...
Simulation models were developed to explore the reversible nature of gecko dry
adhesion system. The central idea of this model is that even with a small moment imparted on the contact tip, the seta can be easily ad-adhered. It is shown that this contact condition is very sensitive, but can...
Zebrafish (Danio rerio) have become an increasingly important model organism for cancer research. There are several cancer models in which neoplasms are induced chemically or genetically. However, spontaneous (unknown etiology) neoplasms are rather common in zebrafish, particularly in older fish. For over a decade, spontaneous intestinal neoplasia and preneoplastic intestinal...
This thesis presents a method for determining range
of body motion for a walking machine with feet fixed on
the ground. The darkling beetle was selected as the
sample subject in this study.
A closed form inverse kinematic solution is used to
determine if a point in space is within...
A foundation for the control of tumors is presented,
based upon the formulation of a realistic, knowledge-based
mathematical model of the interaction between tumor cells
and the immune system. The parametric control variables
relevant to the latest experimental data, e.g., the sigmoidal
dose-response relationship and Michaelis-Menten dynamics,
are also considered....