Bioavailability of selenium (Se) in processed tuna and
wheat products was studied in humans and rats. The protein
source of the rat diets was torula yeast with Se supplied by
either raw, precooked or canned tuna, or whole wheat flour,
bread or bran. Sodium selenite was used as a control....
Selenoprotein W (SeW) is a protein whose function is unknown, but potentially plays a vital role in calcium metabolism, as an indirect link has been established with white muscle disease (WMD). White muscle disease occurs in selenium deficient animals, and is characterized by the precipitation of calcium in muscle, leading...
Rat selenoprotein W (SeW) promoter activity was investigated using different concentrations of cadmium, copper, and zinc. Two fragments (404bp and 1265bp) of the SeW promoter, containing a single metal response element (MRE), were ligated into the multiple cloning site of a pGL3-Basic reporter plasmid. The constructs were transfected into cultured...
The objective of this study was to further determine the distribution of
selenoprotein W (SeW) in tissues from rats and sheep fed different selenium levels and to
search for the possible functions of this protein. In the rat study a total of 28 rat tissues
were examined and SeW was...
The objective of our study was to investigate the effect of selenium on
selenoprotein W. Western blot analysis indicated that selenoprotein W is present in
muscle, brain, testis and spleen of rat tissues. Tissue distribution of selenoprotein W
was not altered in rats fed various selenium levels. Among muscle, brain,...
Studies were conducted to investigate the metabolism of
selenium (Se) , and the influences of Se on the metabolism of cadmium (Cd) and inorganic mercury (Hg) in rats, and in ram semen in
vitro. Se-deficient (-Se) or Se-adequate (+Se) rats were injected intraperitoneally with either ¹⁰⁹CdCl₂ (5 μCi/rat) or ²⁰³HgN0₃...