Index Catalog // ScholarsArchive@OSU

Superior Anti-tumor Activity Exhibited From a Gemcitabine Prodrug Incorporated into Lecithin-Based Nanoparticles

Creator:: Sandoval, Michael
Abstract:: Cancer is class of diseases that has great diversity and unfortunately is one of the leading causes of death in the United States. Chemotherapy remains an important cancer treatment modality, and superior chemotherapeutic drugs are constantly being sought. Gemcitabine is an anti-tumor chemotherapeutic drug and it is the first line...
Resource Type:: Poster, Undergraduate Thesis, and Presentation

Integration of an expert system and dynamic programming approach to optimize log breakdown using 3-dimensional log and internal defect shape information

Creator:: Zeng, Yimin
Abstract:: A computer program, SAW3DG, was developed to optimize log breakdown using 3-dimensional log and internal defect shapes. The program was based on SAW3D, a log breakdown optimization program considering only 3-dimensional log shape. SAW3D was modified to include internal log defects in 3-dimensional representation and integrated with SLGRADER, an expert...
Resource Type:: Dissertation

Pharmacokinetic/pharmacodynamic modeling/simulation and novel gastric retention formulation

Creator:: Kwon, Hyojong
Abstract:: This dissertation describes formulation of a gastric retention device (GRD) and sustained release (SR) hydrochlorothiazide beads at Oregon State University. Formulation condition and amounts of excipients had significant influence on characteristic of the GRD. The GRD containing SR hydrochlorothiazide beads was employed to assess bioavailability/bioequivalency study in healthy subjects. An...
Resource Type:: Dissertation
Full Text:: major committee, Professor J. Mark Christensen and Professor Rosita J. Rodriguez for being untiring

Applications of GnRH immunization in domestic dogs

Creator:: Donovan, Caitlin Elizabeth
Abstract:: Reproductive function in the dog is controlled by feedback mechanisms that involve the hypothalamus, the anterior pituitary gland, and the gonads. Surgical gonad removal, a common procedure performed in dogs for the purposes of sterilization, disrupts the hypothalamic-pituitary-gonadal (HPG) axis and results in permanently elevated concentrations of gonadotropins. Manipulation of...
Resource Type:: Masters Thesis
Full Text:: ......................................................... 106 Appendix J: GnRH Antibody ELISA Protocol

Development and in vivo testing of novel hydrochlorothiazide gastric retention formulations in healthy volunteers and stage I hypertensive patients

Creator:: Farid, Samar Farghali
Abstract:: This thesis describes in vitro and in vivo evaluation of a gastric retention formulation (GRF) developed at Oregon State University. The formulation was prepared from xanthan gum and locust bean gum as gelling agents and other formulation ingredients were added, then it was originally vacuum oven dried. The effect of...
Resource Type:: Dissertation
Full Text:: . I am especially grateful to my committee members Dr. J. Mark Christensen, Dr. Doug Stennett and Dr

Development of enteric protected vaccines for aquaculture

Creator:: Piganelli, Jon D.
Abstract:: At present all vaccines for fish are primarily delivered either by injection or immersion which introduces added stress and labor. A more attractive method of vaccine delivery is oral administration using an enteric protection system, Enteric Coated Antigen Microspheres (ECAMs), which can be utilized for a variety of antigenic forms....
Resource Type:: Dissertation

Rational vaccine development 1) Design of a Triantigen Nasal Anthrax Vaccine Candidate 2) A Novel Lecithin Based Nanoparticle as a Vaccine Delivery System

Creator:: Sloat, Brian R.
Abstract:: Currently, the only anthrax vaccine licensed for human use in the United States is the Anthrax-vaccine-absorbed (AVA or Biothrax®). AVA suffers from several drawbacks, including a complicated and lengthy dosing schedule that requires six initial injections administered over eighteen months, followed by annual boosters. Therefore, a new generation anthrax vaccine...
Resource Type:: Dissertation
Full Text:: . Mark Christensen, Dr. Rosita Proteau, Dr. Virginia Lesser, and Dr. Mark Hoffman for their

Formulation and pharmacokinetics of melatonin

Creator:: Konsil, Julraht
Resource Type:: Dissertation
Full Text:: . J. Mark Christensen, Dr. Joseph A. Mc-Guire, and Dr. Michael J. Burke for their valuable advice and

The Effects of the Flow Regime on Stream Channel Form and Processes

Creator:: Hempel, Laura A.
Abstract:: Numerous studies have explored how alluvial channel size and morphology are adjusted to different sediment and flow conditions, yet we still know very little about how and to what degree the flow regime controls channel form and processes. We use the term ‘channel form’ to refer to the size and...
Resource Type:: Dissertation

Managed artificial aquifer recharge and hydrological studies in the Walla Walla Basin to improve river and aquifer conditions

Creator:: Petrides Jiménez, Arístides Crisóstomos
Abstract:: This research project focuses on the Walla Walla River Basin located on the east side of the states of Oregon and Washington, USA. With the support and collaboration of the Walla Walla Basin Watershed Council, this work embraces four research topics. The first topic includes the feasibility study of artificial...
Resource Type:: Dissertation
Full Text:: members: Yutaka Hagimoto, Lisa Madsen, Larry Enochs, J. Mark Christensen and in particular, my major

ScholarsArchive@OSU

Superior Anti-tumor Activity Exhibited From a Gemcitabine Prodrug Incorporated into Lecithin-Based Nanoparticles

Integration of an expert system and dynamic programming approach to optimize log breakdown using 3-dimensional log and internal defect shape information

Pharmacokinetic/pharmacodynamic modeling/simulation and novel gastric retention formulation

Applications of GnRH immunization in domestic dogs

Development and in vivo testing of novel hydrochlorothiazide gastric retention formulations in healthy volunteers and stage I hypertensive patients

Development of enteric protected vaccines for aquaculture

Rational vaccine development 1) Design of a Triantigen Nasal Anthrax Vaccine Candidate 2) A Novel Lecithin Based Nanoparticle as a Vaccine Delivery System

Formulation and pharmacokinetics of melatonin

The Effects of the Flow Regime on Stream Channel Form and Processes

Managed artificial aquifer recharge and hydrological studies in the Walla Walla Basin to improve river and aquifer conditions

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