The first asymmetric synthesis of (-)-7-epicylindrospermopsin via intramolecular nitrone cycloaddition is described. The synthesis utilized a convergent approach to prepare the cycloaddition precursor 176, which was assembled by condensation of hydroxylamine 175 with aldehyde 145. Hydroxylamine 175 was synthesized from ethylene glycol (166) in seven steps. Aldehyde 145 was completed...
This thesis presents a novel design for a rheometer style viscometer by implementing high temperature and inert atmospheric requirements on the device. The goals of this device are to measure the viscosity of high temperature molten salts, which are corrosive and extremely hydroscopic. It also aims to be able to...
While human tool-use proficiency helped define our history, the cognitive and perceptual mechanics of how humans use tools are not fully understood. This question is of great value to the design of hand-held tools and prosthetics. A prominent theory, tool embodiment, suggests that tool use is facilitated by a flexible...
Centerline rumble strips (CLRS) have proven to be a cost-effective safety measure in reducing lane departure crashes. However, there are often unintended consequences associated with the installation of CLRS, particularly in rural mountainous areas or snow zones. These consequences include the accumulation of water and ice on the roadway and...
Thought to be one of the earliest novels written by an enslaved woman, The Bondwoman’s Narrative (c. 1853-61) has had many literary critics point to the various intertextual allusions that author, Hannah Crafts, incorporated in the novel. Scholarship has largely focused on how Crafts borrowed characters and passages directly from...
Forests face health threats from pests and diseases (e.g., mountain pine beetle, emerald ash borer, chestnut blight [CB], Swiss needle cast), and other issues such as climate change. Interventions such as genetic engineering (GE) have shown promise for mitigating some of these threats. CB, for example, has impacted most American...
High Temperature Gas Reactors (HTGRs) are positioned to disrupt local and global markets via their unique ability to produce carbon-free process heat, high efficiency power generation, and passively safe operational features. However, significant impediments still exist to delay deployment of this particular technology, including a lack of experimental data, verified...
Many projects fail because employees and managers have different understandings of project "success" or "value". Other projects fail because managers are unable to effectively align organizational values with those of their employees. This problem is widely understood, but there is little empirical research that specifies the nature and effect of...
Organizational trust refers to the tendency of individuals or groups within an organization to trust each other. Tschannen-Moran (2004) describes trust as one's "willingness to be vulnerable to another based on the confidence that the other is benevolent, honest, open, reliable, and competent" (p. 17). The purpose of this study...
Oregon State University has conducted research in collaboration with TerraPower, LLC,
to perform a top-down scaling analysis of an integrated test facility. The goal of this
facility is to simulate transient and quasi-steady phenomena at a reduced scale,
including steady-state operation, pump coastdown, natural circulation, reactor head heat
transfer, and...