Index Catalog // ScholarsArchive@OSU

Investigation of the effects of cryopreservation on cellular viability and mechanical integrity of the intervertebral disc

Creator:: Forcier, Ryan J.
Abstract:: Degeneration of the intervertebral disc (IVD) is a phenomenon that has yet to be adequately addressed. Treatment options remain limited and incomplete. The ability to effectively cryopreserve IVDs would allow for better allograft transplantations and storage of samples for research purposes. This study aimed to assess how cryopreservation with different...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Adam Higgins, Committee Member, representing Bioengineering

Development and Optimization of Medicinal Infused Hydrogel Patch and Cloth for the Treatment of Burn Patients

Creator:: Carpenter, Molly E.
Abstract:: Rapid and effective treatment of burn injuries is critical to prevent long term damage. Besides the pain associated with the burn injury due to damage and death of surrounding tissue and cells, there is a large risk for complications, particularly infection, following a burn injury. To address these risks, Meta...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Adam Higgins, Committee Member, representing Bioengineering

Bioactive and Biocompatible Coatings for Endotoxin Capture in Treatment of Sepsis

Creator:: Su, Jonathan
Abstract:: Sepsis is a blood infection caused by circulating pathogens and cell wall fragments that affects over 1 million patients per year in the United States. When bacterial cell membranes are lysed by antibiotics, cell wall fragments containing lipopolysaccharides (LPS) are released. As a result, the capture of LPS is critical...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Adam Higgins, Committee Member, representing Chemical, Biological, and Environmental Engineering

Fused Filament Fabrication of Filled Polymers for Metal Additive Manufacturing

Creator:: Barmore, Brenton
Abstract:: Additive manufacturing (AM) is a relatively new manufacturing technique that can create high complexity parts out of many materials in low volume. The fused filament fabrication (FFF) is the lowest cost AM process and is capable of producing only thermoplastic components. Powder injection molding (PIM) is a high volume low...
Resource Type:: Masters Thesis
Full Text:: sincere appreciation to… Professors Sundar V. Atre, David P. Cann, W.E. “Skip” Rochefort, and Adam Z

Analysis and Modeling of Kinetic Parameters for Urea Hydrolysis by Bacteria for Use in Calcium Carbonate Precipitation in Aquifers

Creator:: Neighbor, Christopher J.
Abstract:: The use of ureolytic bacteria for the remediation of contaminated groundwater aquifers by inducing calcium carbonate precipitation is being studied in order to establish a better understanding of the modeling and prediction of how the bacteria will act in situ. This research has pursued the use of various ureolytic bacteria...
Resource Type:: Honors College Thesis
Full Text:: members Dr. Adam Higgins and Dr. Joe McGuire for their understanding and helpfulness. Thank you to the

Hydroelastic modeling of a wave energy converter using the arbitrary Lagrangian-Eulerian finite element method in LS-DYNA

Creator:: Meicke, Stephen A.
Abstract:: This thesis investigates the applicability of the finite element method to model wave energy converter (WEC) hydroelasticity using LS-DYNA. The proposed methodology uses the Arbitrary Lagrangian-Eulerian formulation to model Fluid-Structure Interaction (FSI) between the WEC and the fluid elements. This formulation allows for time-domain modeling of higher order effects such...
Resource Type:: Masters Thesis

Chandler Loop Model for the Development of Dynamic Hemocompatibility Assays

Creator:: Hasbrook, AnneMarie V.
Abstract:: A common issue with extracorporeal medical devices is blood clotting due to bio-incompatibility. Systemic anticoagulants are often prescribed to mitigate the coagulation issues. However, such drugs can lead to further complications, for example hemorrhaging. One solution to improve the hemocompatibility of blood-contacting medical devices are biomaterials, such as slippery liquid...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Adam Z. Higgins, Committee Member, representing Bioengineering

Predicting Treatment Options for the Intervertebral Disc: Patient-Specific Finite Element Models

Creator:: Ahrens, Sonia R.
Abstract:: This work describes a method for incorporating patient data into a nutrient transport model of the intervertebral disc.This data was collected using MRI diffusion weighted imaging (DWI), and was converted into an apparent diffusion coefficient map (ADC map). This map was used to define the diffusion behavior of water within...
Resource Type:: Honors College Thesis
Full Text:: ___________________________________________________________________________________________________ Adam Higgins, Committee Member, representing Bioengineering

Assessment of roles for the Rho-specific guanine nucleotide dissociation inhibitor (RhoGDI) Ly-GDI in platelet function

Creator:: Thierheimer, Marisa
Abstract:: Platelets undergo morphological changes essential to hemostasis upon activation at sites of vascular injury. The Rho GTPases Rac1, Cdc42, and RhoA drive these changes. Rho guanine nucleotide dissociation inhibitors (RhoGDIs) bind to the Rho GTPases to block the GDP from dissociating from the Rho GTPases, as well as anchoring the...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Adam Higgins, Committee Member, representing the school of Chemical, Biological, and

Characterization of Oxide Growth of Aluminum Alloy 6061 for Nuclear Research and Test Reactors

Creator:: Wei, Youran
Abstract:: Oxide growth is a common phenomenon on aluminum alloy cladding surfaces in nuclear research and test reactors. Without better understanding of oxide growth, excessive oxide build up on the cladding surface reduces heat transfer capability from fuel to coolant and causes safety concerns due to the potential cladding rupture or...
Resource Type:: Masters Thesis
Full Text:: Fast, David Garfinkel, Fei Teng, Benjamin Adam and Lucas teeter in reviewing the thesis and providing

ScholarsArchive@OSU

Investigation of the effects of cryopreservation on cellular viability and mechanical integrity of the intervertebral disc

Development and Optimization of Medicinal Infused Hydrogel Patch and Cloth for the Treatment of Burn Patients

Bioactive and Biocompatible Coatings for Endotoxin Capture in Treatment of Sepsis

Fused Filament Fabrication of Filled Polymers for Metal Additive Manufacturing

Analysis and Modeling of Kinetic Parameters for Urea Hydrolysis by Bacteria for Use in Calcium Carbonate Precipitation in Aquifers

Hydroelastic modeling of a wave energy converter using the arbitrary Lagrangian-Eulerian finite element method in LS-DYNA

Chandler Loop Model for the Development of Dynamic Hemocompatibility Assays

Predicting Treatment Options for the Intervertebral Disc: Patient-Specific Finite Element Models

Assessment of roles for the Rho-specific guanine nucleotide dissociation inhibitor (RhoGDI) Ly-GDI in platelet function

Characterization of Oxide Growth of Aluminum Alloy 6061 for Nuclear Research and Test Reactors

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