Director David Fincher’s films contain many distinct elements that set his work apart, but one of the most instantly recognizable elements is his visual style – specifically, his camerawork. The level of control and purposefulness that Fincher exhibits in his films qualify Fincher as the auteur, or “author,” of his...
The statistical correlations between habitual diet and plasma
risk factors for coronary heart disease CHD were analyzed using
multiple regression. Thirty-one male subjects between 30-56 years
kept complete dietary records for 7 days. Daily means of nutrient
consumption were calculated using a computerized data base.
Fourteen independent variables (total kilocalories,...
For safety critical complex systems, reliability and risk analysis are important design steps. Implementing these analyzes early in the design stage can reduce costs associated with redesign and provide important information on design viability. In the past several years, various research methods have been presented in the design community to...
While many organizations claim to "put safety first," safety is rarely considered early in the design process when system-level architectural decisions are made. Instead, system design follows an abstraction-to-detail process to first meet functional and then performance requirements. Following this process, safety assurance occurs in the later stages of design...
The dissertation examines the effect of two separate yet significant individual level factors—physical and cognitive traits—on entrepreneurial outcomes. The physical factor on which the dissertation focuses is the entrepreneur’s vocal cues and the cognitive traits that the dissertation investigates are the entrepreneur’s goal orientation and his/her ability to take perspectives....
DNA damage, if not repaired, can become a mutation. Mutation
accumulation is associated with initiation and progression of tumorigenesis. DNA
mismatch repair (MMR) is required for maintaining genetic stability by repairing
replication errors. Biochemical studies have shown that MMR also recognizes
mismatch-causing DNA lesions, suggesting the role of MMR in...
An open area of research in complex systems is to move reliability and failure assessments earlier in the engineering design process. When compared to later design, early decisions are cost effective and have a large impact on the system. Standard methods are limited by the availability of data and often...
Integrated Ocean Drilling Program (IODP) Expedition 316 Sites C0006 and C0007 examined the
deformation front of the Nankai accretionary prism offshore the Kii Peninsula, Japan. In the drilling area,
the frontal thrust shows unusual behavior as compared to other regions of the Nankai Trough. Drilling
results, integrated with observations from...
More than 30 members of the diverse amphidinolide family of biologically active macrolides have been isolated over last three decades. From this family, amphidinolides C and F stand among the most complex and densely functionalized affiliates. Recently, we have accomplished the first total synthesis of amphidinolide F. The all-carbon framework...