Background: Clostridium difficile is the main cause of nosocomial infections including antibiotic associated diarrhea, pseudomembranous colitis and toxic megacolon. During the course of Clostridium difficile infections (CDI), C. difficile undergoes sporulation and releases spores to the colonic environment. The elevated relapse rates of CDI suggest that C. difficile spores has...
A unique tumor targeted method, which may be able to deliver a molecule to the surface of a tumor cell using the pH gradient between hypoxic tumor cells and normal tissue has recently been developed. Since solid tumors have been found to have a lower extra cellular pH compared to...
The increased severity of Clostridium difficile infection is primarily attributed to the appearance of an epidemic strain characterized as PCR ribotype 027. The only report that identified epidemic C. difficile ribotype 027 in an American country outside of North America comes from Costa Rica, raising the possibility that strains 027...
Clostridium difficile is an important nosocomial pathogen that has become a major cause of antibiotic-associated diarrhea.
There is a general consensus that C. difficile spores play an important role in C. difficile pathogenesis, contributing to infection,
persistence, and transmission. Evidence has demonstrated that C. difficile spores have an outermost layer,...
Single nucleotide polymorphisms (SNPs) are the most common DNA polymorphisms in plant and animal genomes. SNPs were identified in the allele sequences of up to 12 sunflower (Helianthus annuus L.) genotypes for a genome-wide sample of 81 loci originally mapped using restriction fragment length polymorphism (RFLP) markers. The RFLP loci...
Resistance training is widely prescribed for rehabilitation of injuries and as a method to improve athletic performance. It is accepted that resistance training increases the maximal force production of whole muscle and it has been suggested that the velocity of shortening can increase as well. However, little is known about...
Purpose of the Study The purpose of this study was to: (1) develop a model for predicting high school students' occupational choice satisfaction by measuring the impact of vocational education programs on career decisions, and (2) to examine the validity and the efficiency of the model by testing it on...
The purpose of this study was to develop and validate a self-esteem inventory
for Thai college women. Research questions included whether or not the developed
inventory proved to be unidimensional or multidimensional and, if the
latter proved to be the case, how many dimensions underlie the construct. The
item pool...
While it is generally assumed that alcohol consumption
plays some role in the advent of negative sexual outcomes
among college students (sexually transmitted diseases,
unplanned pregnancies, and date rape), that role has not
been empirically demonstrated or quantified.
The purpose of this study was to assess the association
of alcohol...
We investigated 32 net primary productivity (NPP) models by assessing skills to reproduce integrated NPP in the Arctic Ocean. The models were provided with two sources each of surface chlorophyll-a concentration (chlorophyll), photosynthetically available radiation (PAR), sea surface temperature (SST), and mixed-layer depth (MLD). The models were most sensitive to...