Several compounds have been recently identified which are effective against dengue virus, a tropical arbovirus highly prevalent in southeast Asia and central America. Initial intrinsic fluorescence characterization of the mechanism of action of compound B reveals binding affinity to the dengue capsid protein. A molecular beacon unwinding assay and malachite...
Literature exploring the use of soil conservation
practices has generaly lacked a theoretical
framework. This study proposes a decision-making
model comprised of physical, personal, economic, and
institutional factors. Data from Monroe County,
Missouri, are used to test the hypothesized relationships
of explanatory variables to variations in nurnber
of practices used...
Spreadsheets are arguably the most widely used programming language in use today, yet spreadsheets commonly contain errors. Research shows that regardless of the experience of the end user, an alarming number of spreadsheets contain errors (91% in recent field audits). Most spreadsheets are created by end users with little or...
Met is a prognostic indicator of colorectal cancer patient survival. Therapies that target Met may therefore have beneficial outcomes in the clinic. Recently, EGCG was reported to suppress Met activation, although the mechanisms were not elucidated. HCT116 and HT29 human colon cancer cells were used to examine the relationships between...
Over the past decade, changes in health, economic, and social policies have shifted the dying process out of hospitals and into the community. This exploratory,hypothesis-generating study investigated positive and negative caregiving as well as care management resources of community-based end-of-life caregivers and how they related to caregivers' personal growth following...
The thermal contact conductance (TCC) between two machined pieces of stainless steel was studied. A guarded hot plate thermal conductivity test fixture was designed and built for the experiment. Factors investigated included the contact pressure, surface roughness, interface material and average test temperature. The contact pressure at the interface ranged...
Native point defects, defect complexes, and oxygen impurities in BaCuChF were studied using density
functional theory calculations, self-consistent thermodynamic simulations, and various experimental techniques.
Unintentional p-type conductivity in BaCuChF is explained by the presence of copper vacancies with
transition levels in the valence band. These acceptor-like defects are partially compensated...