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Creator:: Coleman, Daniel J.
Abstract:: Melanoma is the deadliest form of skin cancer, arising from malignant transformation of pigment-producing melanocytes. The primary risk factor for melanoma and other skin cancers is DNA damage resulting from unprotected solar ultraviolet radiation (UVR). If incorrectly repaired, this damage can result in incorporation of mutations that cause aberrant cell...
Resource Type:: Dissertation
Full Text:: is the deadliest form of skin cancer, arising from malignant transformation of pigment-producing

Creator:: Chagani, Sharmeen
Abstract:: Cutaneous melanoma remains the deadliest form of skin cancer arising from malignant transformation of pigment-producing melanocytes, with a diagnosis of metastasis indicating a median survival rate of less than a year. Solar ultraviolet (UV) radiation, especially childhood sun exposure, is an important etiological risk factor of melanoma. This DNA damage...
Resource Type:: Dissertation
Full Text:: melanoma remains the deadliest form of skin cancer arising from malignant transformation of pigment

Creator:: Paquette, Colleen Elizabeth
Abstract:: Zebrafish (Danio rerio) have become an increasingly important model organism for cancer research. There are several cancer models in which neoplasms are induced chemically or genetically. However, spontaneous (unknown etiology) neoplasms are rather common in zebrafish, particularly in older fish. For over a decade, spontaneous intestinal neoplasia and preneoplastic intestinal...
Resource Type:: Masters Thesis
Full Text:: for cancer research. There are several cancer models in which neoplasms are induced chemically or

Creator:: Zwida, Khawla
Abstract:: Throughout most of the developed world, surgical sterilization via gonadectomy has become a common tool for combating the overpopulation of unwanted dogs as well as to eliminate the risk of reproductive diseases in pet dogs. In the dog as in other normal adult mammal, the hypothalamus secretes gonadotropin-releasing hormone (GnRH),...
Resource Type:: Masters Thesis
Full Text:: reproductive diseases in pet dogs (e.g. mammary gland cancer and prostate hyperplasia /infection). In the

Creator:: Xu, Tanjin
Abstract:: An important impact of the genome technology revolution will be the elucidation of mechanisms of cancer pathogenesis, leading to improvements in the diagnosis of cancer and the selection of cancer treatment. Integrated with current well-studied massive knowledge and findings about the role of protein-coding mutations in cancer, demystifying the functional...
Resource Type:: Masters Thesis
Full Text:: for Cancer Noncoding Mutation Recurrence Abstract approved: Stephen A. Ramsey An important impact

Creator:: Stenberg, John C.
Abstract:: Two strains of Escherichia coli were studied to determine the effect of constitutive expression of the SOS DNA damage repair response on the activity of ribonucleotide reductase. Activity of the reductase and cellular deoxynucleoside triphosphate (dNTP) pools were both determined before and after exposure of the cells to ultraviolet radiation....
Resource Type:: Honors College Thesis
Full Text:: and the Incidence of and Attitudes toward Skin Cancer in Several Western Nations. Abstract Approved

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