Graduate Thesis Or Dissertation
 

SIMstat: Wireless, Highly-Reconfigurable Electrochemical Analog Front-End for Point-of-Care Diagnostics and Continuous Monitoring

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https://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/c821gs98t

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  • Within the past decade, the continued-scaling of CMOS processes and improvements in industry mixed-signal integrated-circuit designs have enabled a rapid decrease in the cost, form-factor, and power for point-of-care diagnostics and electrochemical instrumentation. Similarly, advances in low-power RF designs have prompted entire System-on-Modules supporting widely varied Internet-of-Things (IoT) applications. The future of medical device innovations will leverage these technologies to enable the continuous monitoring of physiological parameters, of which can be received by smart devices, personal computers or the cloud for analysis. In this work, we demonstrate a novel, low-cost, BLE-enabled electrochemical sensing platform viable for wearable, real-time analysis of body analytes. With an ESP32 microcontroller connected to the state-of-the-art AD5941 analog front-end, we demonstrate a full system which can receive commands via MATLAB to sense and transmit four clinically meaningful parameters for chronic wound monitoring: temperature, pH, humidity, and analyte concentration. By open sourcing our software and hardware designs, we hope to increase the impact and usage of the sensor platform within the academic community, allowing collaborators to build upon our work for their engineering applications.
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  • Ongoing Research
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  • 2022-06-20 to 2023-07-20

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