Honors College Thesis
 

Detection of koi herpes virus in post-mortem koi

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https://ir.library.oregonstate.edu/concern/honors_college_theses/7m01bv332

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  • Cyprinid herpesvirus 3 (CyHV-3), also known as koi herpesvirus (KHV), is a pathogenic and highly contagious virus that affects the Cyprinus genus. The mortality rate of the KHV infection is around 80-100%. KHV can become latent in the recovered koi and reactivate under stressful conditions. KHV can reactivate under various stress conditions, such as temperature, predation, and other concurrent infections. It is unknown whether KHV will reactivate from latency in a host that dies within a 24-hour period. To determine whether KHV reactivation occurs in recently deceased koi, the presence of KHV DNA was investigated in tissues harvested from three dead koi that were latently infected with KHV. KHV DNA, ranging from 50 to 5 x 102 DNA copies per ug, was detected in the gills and kidneys of those dead koi. Gill tissue had the highest viral concentration in two of the three koi tested. This study suggests that KHV may reactivate in the dying koi and shed virions via the gill tissue to spread the virus.
  • Keywords: KHV, Koi Herpesvirus, Cyprinid Herpesvirus
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