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Filtering by: Creator Frasier, Kaitlin E. Remove constraint Creator: Frasier, Kaitlin E. Decade 2020-2029 Remove constraint Decade: 2020-2029

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  • Developing a Modular Analysis Pipeline to Identify Critical Matrisome Components in Gynecological Disease

    Creator:
    Cook, Carson J.
    Abstract:
    The matrisome is an ensemble of genes that are highly relevant for characterizing the behavior of the extracellular matrix (ECM) during the onset and progression of many diseases. Recent advances in the definition of the matrisome, such as The Matrisome Project, have been instrumental in making more advanced resources available...
    Resource Type:
    Masters Thesis
    Full Text:
    . Abstract approved: Kaitlin C. Fogg The matrisome is an ensemble of genes that are

  • Chandler Loop Model for the Development of Dynamic Hemocompatibility Assays

    Creator:
    Hasbrook, AnneMarie V.
    Abstract:
    A common issue with extracorporeal medical devices is blood clotting due to bio-incompatibility. Systemic anticoagulants are often prescribed to mitigate the coagulation issues. However, such drugs can lead to further complications, for example hemorrhaging. One solution to improve the hemocompatibility of blood-contacting medical devices are biomaterials, such as slippery liquid...
    Resource Type:
    Honors College Thesis
    Full Text:
    :_____________________________________________________ Joe E. Baio A common issue with extracorporeal medical devices is blood clotting due

  • Circadian Clock Disruption via Exposure to Extended Light at Night (LAN) Alters Epigenetic Expression of CKI Genes in the Murine Mammary Gland

    Creator:
    Rogers, Zackry L.
    Abstract:
    Breast cancer is a leading cause of cancer deaths among women, with an estimated 12.4% of American women diagnosed with this tumor type. Evidence suggests that exogenous disruptors can exert epigenetic changes leading to aberrant gene expression, shifting the cellular balance toward oncogenesis. While chemical pollutant exposure is well-studied, light...
    Resource Type:
    Honors College Thesis
    Full Text:
    ) Corresponding e-mail address: rogerzac@oreongstate.edu ©Copyright by Zackry L. Rogers June 3, 2022

  • Luteinizing hormone receptor-mediated cell proliferation in canine T-cell lymphoma cells

    Creator:
    Flint, Camryn
    Abstract:
    Luteinizing hormone (LH) is secreted in low-amplitude pulses in sexually intact dogs to stimulate synthesis of estrogen and testosterone in females and males, respectively. LH is mainly considered a reproductive hormone, but LH receptors (LHR) have been identified in non-reproductive tissues, including in canine lymphoma and isolated canine T-cell lymphoma...
    Resource Type:
    Honors College Thesis
    Full Text:
    Kaitlin Curran, Committee Member, representing Veterinary Medicine Susan Pisias

  • Visualizing Internalization of Mesenchymal Stem Cell-Derived Extracellular Vesicles by Canine Osteosarcoma Cells

    Creator:
    Bilal, Jumanah
    Abstract:
    Osteosarcoma (OSA) is a primary malignant bone tumor sarcoma that occurs in dogs as well as people and has aggressive biologic behavior with devastating consequences. Because of the similarities in morphology and prognosis, OSA in dogs represents an effective model for the equivalent disease in humans. Mesenchymal stem cells (MSCs)...
    Resource Type:
    Honors College Thesis
    Full Text:
    Words: cancer, dog, mesenchymal stem cell, osteosarcoma, extracellular vesicle Corresponding e-mail

  • Material science in menstrual health and hygiene

    Creator:
    Aduviri, Brooke
    Abstract:
    Menstrual health and hygiene insecurity is a global health issue people across the world face, particularly in developing countries. According to the World Bank, an estimated 500 million lack access to adequate menstrual products, and “to effectively manage their menstruation, women and girls require access to water, sanitation, and hygiene...
    Resource Type:
    Honors College Thesis
    Full Text:
    : Menstruation, Polymer, Nonwoven, Biodegradability Corresponding e-mail address: aduvirib@oregonstate.edu

  • Investigating the Hemocompatibility of Blood-Contacting Biomaterials

    Creator:
    Hummel, Madeleine H.
    Abstract:
    Surface-associated thrombosis is a critical concern in medical device development. Current extracorporeal circulation units require systemic anticoagulation to avoid thrombosis, which can cause adverse effects such as thrombocytopenia, hypertriglyceridemia, and hyperkalemia. To address this issue, we combine the technology of polydopamine (PDA) functionalization with slippery liquid infused porous surfaces (SLIPS)....
    Resource Type:
    Masters Thesis
    Full Text:
    Abstract approved: ____________________________________________________ Joe E. Baio Surface

  • Phenotyping Degeneration of the Intervertebral Disc with Principal Component Analysis and K-Means Clustering

    Creator:
    Chen, Joseph
    Abstract:
    The human intervertebral disc (IVD) provides support for the vertebral bodies, allowing for movement and load bearing. The IVD can degenerate with age or injury, impeding function and causing chronic pain. Despite disc degeneration affecting over 90% of adults over age 50, and back pain being the leading global cause...
    Resource Type:
    Masters Thesis

  • SIMstat: Hardware Design Considerations for Implementing a Low-Cost, Portable Potentiostat

    Creator:
    Cook, Jacob M.
    Abstract:
    Electroanalytical techniques allow scientists and engineers to characterize bulk solutions as well as interfaces. Potentiostats are commonly used by researchers in a variety of disciplines to analyze the chemistry which occurs at a working electrode surface. Advancements in microelectronics and the proliferation of open-source designs have allowed researchers to construct...
    Resource Type:
    Honors College Thesis
    Full Text:
    : Potentiostat, Cyclic Voltammetry, Bioinstrumentation, Biosensors, Analog Design Corresponding e-mail address

  • Focus ; Spring 2020

    Creator:
    Oregon State University. College of Forestry
    Abstract:
    The magazine of the OSU College of Forestry. FOCUS is published by Oregon State University College of Forestry to keep alumni, friends, faculty, staff and students informed about the college and its many events, activities and programs.
    Resource Type:
    Other
    Full Text:
    Work at College of Forestry labs and facilities informs decisions and prepares future leaders. T H E